Angina
Also known as: Angina Pectoris
Methodology & AI Transparency ⓘ
Angina Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: Angina is chest pain or discomfort you feel when there is not enough blood flow to your heart muscle.
- 2 Real-world patient consensus: Diagnostic registry I20.9: Angina is managed within Heart & Vascular (aka Angina Pectoris).
- 3 Typical cash cost range: Clinicians assessing Angina focus on structural ventricular wall in Angina (I20.9: stress) and targeted history.
- 4 Top reported side effects / signs: Objective lab/clinical target for Angina: High-Sensitivity Troponin I [Angina I20.9] (< 14 ng/L (I20.9)) and Apolipoprotein B (ApoB) [Angina I20.9].
Ask our AI Specialists anything about Angina
What Is Angina?
Angina is chest pain or discomfort you feel when there is not enough blood flow to your heart muscle. Your heart muscle needs the oxygen that the blood carries. Angina may feel like pressure or a squeezing pain in your chest. It may feel like indigestion. You may also feel pain in your shoulders, arms, neck, jaw, or back. Angina is a symptom of coronary artery disease (CAD), the most common heart disease . CAD happens when a sticky substance called plaque builds up in the arteries that supply blood to the heart, reducing blood flow. There are three types of angina: Stable angina is the most common type. It happens when the heart is working harder than usual.
Pathophysiology, Underlying Causes & Clinical Presentation
Pathophysiologically, Angina (ICD-10 I20.9) is driven by structural ventricular wall in Angina (I20.9: stress); Cross-referenced with NIH MeSH (Angina Pectoris), specialists in Heart & Cardiovascular Disease monitor Apolipoprotein B (ApoB) [Angina I20.9] to gauge tissue recovery.
Common Symptoms & Clinical Signs
- • Variant angina is rare. It happens when you are resting. Medicines can help
- • Presentation of Angina (I20.9): shortness of breath in Angina (I20.9: when climbing stairs)
- • Secondary Angina clinical sign: palpitations, skipped beats, in Angina (I20.9: or irregular resting)
- • Symptom flares in Angina correlating with High-Sensitivity Troponin I [Angina I20.9] deviation outside < 14 ng/L (I20.9)
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
Angina Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | I20.9 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | Heart & Cardiovascular Disease | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: High-Sensitivity Troponin I [Angina I20.9] | < 14 ng/L (I20.9) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Apolipoprotein B (ApoB) [Angina I20.9] | < 70 mg/dL (I20.9) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Left Ventricular Ejection in Angina (I20.9: Fraction (LVEF)) | 55% – 70% (I20.9) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for Angina
| Medication | Pharmacologic Class | Patient Worth-It | CMS NADAC / Unit | Typical Lowest Cash |
|---|---|---|---|---|
| Isosorbide Dinitrate Isordil Titradose • RxCUI 381056 | Nitrate Vasodilator | 80% | $0.1852 | $ 6.72 /mo |
| Isosorbide Mononitrate Monoket • RxCUI 311196 | Nitrate Vasodilator | 92% | $0.1631 | $ 83.85 /mo |
| Nifedipine Procardia • RxCUI 198032 | Dihydropyridine Calcium Channel Blocker | 74% | $0.1179 | $ 11.87 /mo |
| Aspruzyo Sprinkle (Ranolazine) Aspruzyo Sprinkle • RxCUI 616749-B47335625 | Anti-anginal | 79% | $0.2954 | $ 29.77 /mo |
| Ranolazine Aspruzyo Sprinkle, Ranexa • RxCUI 616749 | Anti-anginal | 84% | $0.2725 | $ 8.40 /mo |
| Nitroglycerin Rectiv, Nitrostat • RxCUI 198040 | Nitrate Vasodilator | 94% | $0.0619 | $ 19.89 /mo |
| Nicardipine Hydrochloride Cardene IV, Cardene • RxCUI 858613 | Dihydropyridine Calcium Channel Blocker | 75% | $1.1201 | $ 30.81 /mo |
| Nitroglycerin Lingual Nitroglycerin Lingual Generic • RxCUI 705129 | Nitrate Vasodilator | 83% | $0.4761 | $ 27.78 /mo |
| Nadolol Corgard • RxCUI 198006 | beta-Adrenergic Blocker | 74% | $0.1274 | $ 8.83 /mo |
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Angina)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| New Insights on Sertraline treatment of major depression in patients with acute MI or unstable: What a 369-Participant Study Found Our results suggest that sertraline is a safe and effective treatment for recurrent depression in patients with recent MI or unstable angina and without other life-threatening medical conditions. JAMA • 2002-08-14 • Randomized Controlled Trial | N = 369 | 93/100 | PMID 12169073 ↗ |
| New Insights on Association between trajectory of systolic blood pressure and outcomes in heart: What a 3,388-Participant Study Found The decreasing or increasing SBP trajectory is associated with a high risk of heart and blood vessel events in HFpEF, suggesting a stable SBP trajectory group (≈130 mmHg) have lower incidence of heart and blood vessel events... European journal of internal medicine • 2025-01-15 • Phase III Randomized Trial | N = 3,388 | 90/100 | PMID 39419733 ↗ |
| Can This Approach Help? Inside the Latest Research on Testosterone replacement in hypogonadal men with angina improves ischaemic Testosterone replacement therapy in hypogonadal men delays time to ischaemia, improves mood, and is associated with potentially beneficial reductions of total cholesterol and serum tumour necrosis factor alpha. Heart (British Cardiac Society) • 2004-08-15 • Randomized Controlled Trial | Multi-cohort | 88/100 | PMID 15253956 ↗ |
Angina Patient Community & “People Like Me” Threads
Filter Angina community threads and patient logs by age, biological sex, dosage, and treatment duration.