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Dermatology: Acne, Eczema, Psoriasis & Rosacea • ICD-10-CM L23.2

Biopsy

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L23.2 • 8 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Biopsy Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Biopsy?

A biopsy is a procedure that removes cells or tissue from your body. A doctor called a pathologist looks at the cells or tissue under a microscope to check for damage or disease. The pathologist may also do other tests on it. Biopsies can be done on all parts of the body. In most cases, a biopsy is the only test that can tell for sure if a suspicious area is cancer. But biopsies are performed for many other reasons too. There are different types of biopsies. A needle biopsy removes tissue with a needle passed through your skin to the site of the problem. Other kinds of biopsies may require surgery.

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Biopsy (code L23.2) is keratinocyte hyperproliferation [Biopsy L23.2], Cross-referenced with NIH MeSH (Biopsy), which Dermatology: Acne, Eczema, Psoriasis & Rosacea clinicians address while surveilling 25-Hydroxy Vitamin D in Biopsy (L23.2: & hs-CRP) (25(OH)D 40–65 ng/mL (L23.2)).

Common Symptoms & Clinical Signs

  • • Presentation of Biopsy (L23.2): post-inflammatory hyperpigmentation, facial in Biopsy (L23.2: flushing, or pitted)
  • • Secondary Biopsy clinical sign: recurrent flares triggered in Biopsy (L23.2: by UV exposure,)
  • • Symptom flares in Biopsy correlating with 25-Hydroxy Vitamin D in Biopsy (L23.2: & hs-CRP) deviation outside 25(OH)D 40–65 ng/mL (L23.2)
  • • Functional skin & dermatology impact requiring clinical dermatologic lesion in Biopsy (L23.2: morphology exam) evaluation (L23.2)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Biopsy Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L23.2 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Dermatology: Acne, Eczema, Psoriasis & Rosacea NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Biopsy (L23.2: & hs-CRP) 25(OH)D 40–65 ng/mL (L23.2) Clinical Reference Target Range
Diagnostic / Lab Marker: Affected Body Surface in Biopsy (L23.2: Area (BSA /) Clear or Almost Clear (IGA 0–1) (L23.2) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Lipids & in Biopsy (L23.2: ALT (if systemic) Within baseline reference limits (L23.2) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Biopsy)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Endometrial safety and tolerability of triphasic sequential hormone replacement: What a 341-Participant Study Found

The triphasic E2V/MPA regimen was well tolerated and produced endometrial effects similar to those of the two comparators.

Climacteric : the journal of the International Menopause Society • 2004-03-15 • Phase III Randomized Trial
N = 341 93/100 PMID 15259280 ↗
New Insights on Quantitative regression of qFibrosis with resmetirom: Exploratory histologic: What a 966-Participant Study Found

Resmetirom treatment led to significant improvements in qFC, qFS, and individual collagen features associated with fibrosis progression.

Journal of hepatology • 2026-08-15 • Phase III Randomized Trial
N = 966 93/100 PMID 41895606 ↗
New Insights on Optimizing prostate biopsy decision making - (MUSIC-screen): A 1:1 randomized: What a 1,284-Participant Study Found

MUSIC-Screen will determine whether microUS can be used as an imaging modality to inform biopsy decision making that is non-inferior to mpMRI for GG ≥ 2 prostate cancer detection.

Contemporary clinical trials • 2026-09-15 • Phase III Randomized Trial
N = 1,284 90/100 PMID 42476253 ↗
Can This Approach Help? Inside the Latest Research on Secukinumab Reduces Psoriasis-associated severe itching and Regenerates the

SEC was superior to placebo by efficiently controlling reduced severe itching intensity, clinically normalizing skin lesions, and reversing histopathological abnormalities.

Acta dermato-venereologica • 2024-11-20 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 39565228 ↗
Can This Approach Help? Inside the Latest Research on Resmetirom on Noninvasive Endpoints in a 36-Week Phase 2 Active Treatment

In the main and OLE studies, PRO-C3/C3M (matrix metalloproteinase-degraded C3), a marker of net fibrosis formation, was reduced in resmetirom-treated patients (-0.76 [-1.27, -0.24], P = 0.0044 and -0.68, P Conclusion: The...

Hepatology communications • 2021-04-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 33860116 ↗
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