Cat Scratch Disease
Also known as: CSD, Cat scratch fever, Computed tomography, Abrasion, Scrape
Methodology & AI Transparency ⓘ
Cat Scratch Disease Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: Cat scratch disease (CSD) is an illness caused by the bacterium Bartonella henselae.
- 2 Real-world patient consensus: Clinical coding for Cat Scratch Disease uses ICD-10 A28.1 across Migraine & Headache specialty care.
- 3 Typical cash cost range: Clinicians assessing Cat Scratch Disease focus on brainstem trigeminal nucleus in Cat Scratch Disease (A28.1: caudalis sensitization) and targeted history.
- 4 Top reported side effects / signs: Longitudinal Cat Scratch Disease monitoring tracks Monthly Headache Days in Cat Scratch Disease (A28.1: (MHD)) toward < 2 days/month on prevention (A28.1).
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What Is Cat Scratch Disease?
Cat scratch disease (CSD) is an illness caused by the bacterium Bartonella henselae. Almost half of all cats carry the infection at some point. The infection does not make cats sick. However, the scratch or bite of an infected cat can cause symptoms in people, including : Swollen lymph nodes , especially around the head, neck, and upper limbs Fever Headache Fatigue Poor appetite For people with weak immune systems, CSD may cause more serious problems. The best way to avoid CSD is to avoid rough play with cats that could lead to scratches or bites. If you do get a scratch or bite, wash it well with soap and water.
Pathophysiology, Underlying Causes & Clinical Presentation
In Cat Scratch Disease (A28.1), physiological disruption stems from brainstem trigeminal nucleus in Cat Scratch Disease (A28.1: caudalis sensitization), Cross-referenced with NIH MeSH (Cat-Scratch Disease), informing Migraine & Headache Disorders protocols that track MIDAS Disability Score [Cat Scratch Disease A28.1] (Grade I (0 – 5) (A28.1)).
Common Symptoms & Clinical Signs
- • Swollen lymph nodes , especially around the head, neck, and upper limbs
- • Presentation of Cat Scratch Disease (A28.1): nausea, gastric stasis, in Cat Scratch Disease (A28.1: or worsening pain)
- • Secondary Cat Scratch Disease clinical sign: moderate-to-severe unilateral throbbing in Cat Scratch Disease (A28.1: or pulsing head)
- • Symptom flares in Cat Scratch Disease correlating with Monthly Headache Days in Cat Scratch Disease (A28.1: (MHD)) deviation outside < 2 days/month on prevention (A28.1)
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
Cat Scratch Disease Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | A28.1 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | Migraine & Headache Disorders | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: Monthly Headache Days in Cat Scratch Disease (A28.1: (MHD)) | < 2 days/month on prevention (A28.1) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: MIDAS Disability Score [Cat Scratch Disease A28.1] | Grade I (0 – 5) (A28.1) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: RBC Magnesium & in Cat Scratch Disease (A28.1: Riboflavin Status) | RBC Mg 5.0 – 6.4 mg/dL (A28.1) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for Cat Scratch Disease
Treatment selection for Cat Scratch Disease depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Cat Scratch Disease)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| New Insights on Treatment of chronic migraine with Botox (onabotulinumtoxinA): Development,: What a 5,000-Participant Study Found Benefits also include improvements in quality of life, fewer psychiatric comorbidities, and reduced healthcare resource utilization. Medicine • 2023-07-01 • Phase III Randomized Trial | N = 5,000 | 96/100 | PMID 37499085 ↗ |
| New Insights on Eptinezumab improved patient-reported outcomes in patients with migraine and: What a 1,072-Participant Study Found This subgroup analysis in patients with CM/MOH at baseline suggests that eptinezumab treatment is associated with early, sustained, and clinically meaningful improvements in patient-reported outcomes. Headache • 2023-02-15 • Phase III Randomized Trial | N = 1,072 | 96/100 | PMID 36633219 ↗ |
| New Insights on Erenumab treatment for migraine prevention in Japanese patients: real-world: What a 261-Participant Study Found Treatment with erenumab 70 mg once monthly demonstrated favorable real-world benefits and safety findings in Japanese patients with EM or CM. Headache • 2021-06-15 • Phase III Randomized Trial | N = 261 | 93/100 | PMID 34153117 ↗ |
| Can This Approach Help? Inside the Latest Research on Baseline Characteristics on the real-world benefits and safety of Eptinezumab in Demographic and baseline characteristics were similar across treatment groups in both the PROMISE-1 and the PROMISE-2 studies. Clinical therapeutics • 2022-03-15 • Phase III Randomized Trial | Multi-cohort | 88/100 | PMID 35131090 ↗ |
| Can This Approach Help? Inside the Latest Research on Melatonin for migraine prevention in children and adolescents: A randomized, When compared to recall at enrollment, headache days decreased across the single-blind placebo phase and the gold-standard blind phase. Headache • 2023-10-15 • Randomized Controlled Trial | N = 72 | 88/100 | PMID 37466211 ↗ |
Cat Scratch Disease Patient Community & “People Like Me” Threads
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