Celiac Disease
Also known as: Celiac sprue, Gluten-sensitive enteropathy, Nontropical sprue
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Celiac Disease Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: What is celiac disease? Celiac disease is a chronic (long-term) digestive and immune disorder that damages your small intestine.
- 2 Real-world patient consensus: Diagnostic registry K90.0: Celiac Disease is managed within IBS, IBD & Colon (aka Celiac sprue).
- 3 Typical cash cost range: Primary evaluation for Celiac Disease incorporates celiac serology [Celiac Disease K90.0] and symptom diary review.
- 4 Top reported side effects / signs: Follow-up benchmark in Celiac Disease: maintaining hs-CRP, CBC & in Celiac Disease (K90.0: Ferritin) within Normal hemoglobin; hs-CRP < 1.0 mg/L (K90.0).
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What Is Celiac Disease?
What is celiac disease? Celiac disease is a chronic (long-term) digestive and immune disorder that damages your small intestine. The damage may prevent your body from absorbing vitamins , minerals , and other nutrients from the food you eat. This can lead to malnutrition and other serious health problems. Celiac disease is triggered by eating foods that contain gluten. Gluten is a protein found in wheat, barley, rye, and other grains. It may also be in other products you swallow like vitamins, supplements , toothpaste, mouthwash, and lip balm. Gluten in hair and skin products aren't absorbed through the skin.
Pathophysiology, Underlying Causes & Clinical Presentation
Underlying Celiac Disease (code K90.0) is mucosal tight-junction permeability in Celiac Disease (K90.0: shifts or immune-mediated), Cross-referenced with NIH MeSH (Celiac Disease), which IBS, Crohn, Colitis & Bowel Disorders clinicians address while surveilling hs-CRP, CBC & in Celiac Disease (K90.0: Ferritin) (Normal hemoglobin; hs-CRP < 1.0 mg/L (K90.0)).
Common Symptoms & Clinical Signs
- • Have a family member who has the disease
- • Have Down syndrome , Turner syndrome , or Williams syndrome
- • Presentation of Celiac Disease (K90.0): alternating diarrhea, constipation, in Celiac Disease (K90.0: urgency, or sensation)
- • Secondary Celiac Disease clinical sign: post-meal abdominal distension, in Celiac Disease (K90.0: gas bloating, or)
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
Celiac Disease Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | K90.0 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | IBS, Crohn, Colitis & Bowel Disorders | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: hs-CRP, CBC & in Celiac Disease (K90.0: Ferritin) | Normal hemoglobin; hs-CRP < 1.0 mg/L (K90.0) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Fecal Calprotectin [Celiac Disease K90.0] | < 50 mcg/g (K90.0) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Tissue Transglutaminase IgA in Celiac Disease (K90.0: (tTG-IgA)) | Negative (celiac rule-out) (K90.0) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for Celiac Disease
Treatment selection for Celiac Disease depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Celiac Disease)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| Can This Approach Help? Inside the Latest Research on Safety of Ustekinumab in Inflammatory Bowel Disease: Pooled Safety Analysis of The safety profile of ustekinumab across the pooled inflammatory bowel disease population through 1 year was favorable and generally comparable to placebo. Inflammatory bowel diseases • 2021-06-15 • Phase III Randomized Trial | Multi-cohort | 88/100 | PMID 32964215 ↗ |
Celiac Disease Patient Community & “People Like Me” Threads
Filter Celiac Disease community threads and patient logs by age, biological sex, dosage, and treatment duration.