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Neurology, Stroke & Movement Disorders • ICD-10-CM G51.39

Clonic hemifacial spasm

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM G51.39 • 5 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Clonic hemifacial spasm Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Clonic hemifacial spasm?

Cataloged under federal diagnostic code G51.39 in Brain & Neurology, Clonic hemifacial spasm requires neurorehabilitation tracking [Clonic hemifacial spasm G51.39] so specialists can calibrate treatment intensity against Serum Vitamin B12 in Clonic hemifacial spasm (G51.39: & Methylmalonic Acid) benchmarks.

Pathophysiology, Underlying Causes & Clinical Presentation

Mechanistic hallmarks of Clonic hemifacial spasm (G51.39) center on blood-brain barrier neuroinflammation [Clonic hemifacial spasm G51.39]. targeted brain & neurology interventions aim to normalize Serum Vitamin B12 in Clonic hemifacial spasm (G51.39: & Methylmalonic Acid).

Common Symptoms & Clinical Signs

  • • Presentation of Clonic hemifacial spasm (G51.39): episodic vertigo, imbalance, in Clonic hemifacial spasm (G51.39: coordination drift, or)
  • • Secondary Clonic hemifacial spasm clinical sign: numbness, paresthesia, or in Clonic hemifacial spasm (G51.39: visual field/speech changes)
  • • Symptom flares in Clonic hemifacial spasm correlating with Serum Vitamin B12 in Clonic hemifacial spasm (G51.39: & Methylmalonic Acid) deviation outside B12 > 500 pg/mL; MMA < 240 nmol/L (G51.39)
  • • Functional brain & neurology impact requiring neurorehabilitation tracking [Clonic hemifacial spasm G51.39] evaluation (G51.39)

Clonic hemifacial spasm Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code G51.39 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Neurology, Stroke & Movement Disorders NLM Clinical Tables
Diagnostic / Lab Marker: Serum Vitamin B12 in Clonic hemifacial spasm (G51.39: & Methylmalonic Acid) B12 > 500 pg/mL; MMA < 240 nmol/L (G51.39) Clinical Reference Target Range
Diagnostic / Lab Marker: Carotid Duplex / in Clonic hemifacial spasm (G51.39: Cerebral Perfusion) No hemodynamically significant stenosis (G51.39) Clinical Reference Target Range
Diagnostic / Lab Marker: HbA1c & Blood in Clonic hemifacial spasm (G51.39: Pressure Neuro-Targets) BP < 120/75 mmHg; HbA1c < 5.7% (G51.39) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Clonic hemifacial spasm

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Treatment selection for Clonic hemifacial spasm depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Clonic hemifacial spasm)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Efficacy, safety, and tolerability of adjunctive perampanel in patients from

Adjunctive perampanel (up to 12 mg/day) may be a suitable treatment for Chinese patients with FS, with/without FBTCS, or GTCS, with similar real-world benefits and safety/tolerability compared to non-Chinese patients.

CNS neuroscience & therapeutics • 2021-03-15 • Phase III Randomized Trial
N = 79 88/100 PMID 33340263 ↗
Can This Approach Help? Inside the Latest Research on Dynamics of pseudo-atrophy in RRMS reveals predominant gray matter

Findings reported here add new insights into the complex mechanisms of pseudo-atrophy and its relation to the compartmentalized inflammation occurring in the GM of MS patients.

Annals of clinical and translational neurology • 2021-03-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 33534940 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of adjunctive perampanel in patients with focal seizures or

128 patients (placebo, n = 39; perampanel, n = 89) were included in the gold-standard blind Safety Analysis Set and 126 (FS, n = 113 [placebo, n = 32; perampanel, n = 81]; FBTCS, n = 35 [placebo, n = 14; perampanel, n = 21];...

Epilepsia open • 2021-03-15 • Phase III Randomized Trial
N = 39 88/100 PMID 33681652 ↗
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