Delirium
Also known as: Syrinx, Syringo, Syringeal, Spinal cord
Methodology & AI Transparency ⓘ
Delirium Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: What is delirium? Delirium is a mental state in which you are confused, disoriented, and not able to think or remember clearly.
- 2 Real-world patient consensus: Mapped to Alzheimer, Dementia & Memory Health under ICD-10-CM R41.0 for Delirium clinical workups.
- 3 Typical cash cost range: Clinicians assessing Delirium focus on beta-amyloid [Delirium R41.0] and targeted history.
- 4 Top reported side effects / signs: Key Memory & Cognition biomarkers for Delirium (R41.0): TSH & Fasting in Delirium (R41.0: ApoB / HbA1c) & MoCA Cognitive Screening in Delirium (R41.0: Score) (>= 26 / 30 (R41.0)).
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What Is Delirium?
What is delirium? Delirium is a mental state in which you are confused, disoriented, and not able to think or remember clearly. It usually starts suddenly. It is often temporary and treatable. There are three types of delirium: Hypoactive, when you are not active and seem sleepy, tired, or depressed Hyperactive, when you are restless or agitated Mixed, when you change back and forth between being hypoactive and hyperactive What causes delirium? There are many different problems that can cause delirium. Some of the more common causes include: Advanced cancer . Alcohol or drugs , either from intoxication or withdrawal.
Pathophysiology, Underlying Causes & Clinical Presentation
Delirium (R41.0) alters memory & cognition homeostasis through beta-amyloid [Delirium R41.0]; Cross-referenced with NIH MeSH (Delirium), clinical remission targets MoCA Cognitive Screening in Delirium (R41.0: Score) within >= 26 / 30 (R41.0).
Common Symptoms & Clinical Signs
- • Hypoactive, when you are not active and seem sleepy, tired, or depressed
- • Hyperactive, when you are restless or agitated
- • Presentation of Delirium (R41.0): subtle personality shifts, in Delirium (R41.0: apathy, or evening)
- • Secondary Delirium clinical sign: slowed processing speed in Delirium (R41.0: compared with prior)
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
Delirium Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | R41.0 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | Alzheimer, Dementia & Memory Health | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: TSH & Fasting in Delirium (R41.0: ApoB / HbA1c) | Optimal cardiometabolic neuroprotection (R41.0) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: MoCA Cognitive Screening in Delirium (R41.0: Score) | >= 26 / 30 (R41.0) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Homocysteine & Vitamin in Delirium (R41.0: B12) | Homocysteine < 9 umol/L; B12 > 500 pg/mL (R41.0) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for Delirium
Treatment selection for Delirium depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Delirium)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| Can This Approach Help? Inside the Latest Research on Establishing Clinically Meaningful Change on Outcome Assessments Frequently Used These thresholds may be useful to aid the interpretation of Alzheimer's disease clinical trial data by illustrating meaningful within-patient progression over the course of a clinical trial via supplementary progressor... The journal of prevention of Alzheimer's disease • 2023-01-15 • Phase III Randomized Trial | Multi-cohort | 88/100 | PMID 36641605 ↗ |
| Can This Approach Help? Inside the Latest Research on Incidence of Intensive Care Unit Delirium After Heart Surgery: A Feasibility Chronotherapeutic environmental interventions were feasible and safe in ICU care. Nursing in critical care • 2026-11-15 • Randomized Controlled Trial | Multi-cohort | 82/100 | PMID 42952074 ↗ |
| Can This Approach Help? Inside the Latest Research on Anesthesia-induced electroencephalogram oscillations and perioperative outcomes In this study anesthesia-induced oscillations were associated with postoperative outcomes; however, these were not independently associated with delirium or discharge disposition after considering preoperative cognitive and... Journal of clinical anesthesia • 2025-03-15 • Phase III Randomized Trial | Multi-cohort | 82/100 | PMID 39921932 ↗ |
Delirium Patient Community & “People Like Me” Threads
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