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Heart & Cardiovascular Disease • ICD-10-CM I42.00

Dilated cardiomyopathy

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM I42.00 • 5 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Dilated cardiomyopathy Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Dilated cardiomyopathy?

Under Heart & Cardiovascular Disease diagnostic criteria (I42.00), workup for Dilated cardiomyopathy integrates 12-lead resting electrocardiography [Dilated cardiomyopathy I42.00] with evidence-graded therapy tailored to Apolipoprotein B (ApoB) [Dilated cardiomyopathy I42.00] response.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Dilated cardiomyopathy (I42.00) features subendocardial perfusion deficits [Dilated cardiomyopathy I42.00]. therapeutic stabilization in heart & vascular is verified against Left Ventricular Ejection in Dilated cardiomyopathy (I42.00: Fraction (LVEF)).

Common Symptoms & Clinical Signs

  • • Presentation of Dilated cardiomyopathy (I42.00): shortness of breath in Dilated cardiomyopathy (I42.00: when climbing stairs)
  • • Secondary Dilated cardiomyopathy clinical sign: palpitations, skipped beats, in Dilated cardiomyopathy (I42.00: or irregular resting)
  • • Symptom flares in Dilated cardiomyopathy correlating with Apolipoprotein B (ApoB) [Dilated cardiomyopathy I42.00] deviation outside < 70 mg/dL (I42.00)
  • • Functional heart & vascular impact requiring 12-lead resting electrocardiography [Dilated cardiomyopathy I42.00] evaluation (I42.00)

Dilated cardiomyopathy Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code I42.00 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Heart & Cardiovascular Disease NLM Clinical Tables
Diagnostic / Lab Marker: Apolipoprotein B (ApoB) [Dilated cardiomyopathy I42.00] < 70 mg/dL (I42.00) Clinical Reference Target Range
Diagnostic / Lab Marker: Left Ventricular Ejection in Dilated cardiomyopathy (I42.00: Fraction (LVEF)) 55% – 70% (I42.00) Clinical Reference Target Range
Diagnostic / Lab Marker: NT-proBNP [Dilated cardiomyopathy I42.00] < 100 pg/mL (I42.00) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Dilated cardiomyopathy

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Treatment selection for Dilated cardiomyopathy depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Dilated cardiomyopathy)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Pharmacogenomic Study of Statin-Associated Muscle Symptoms in the ODYSSEY

This study comprises the largest discovery exome-wide and genome-wide association study for atorvastatin- or rosuvastatin-mediated SAMS to date.

Circulation. Genomic and precision medicine • 2022-06-15 • Randomized Controlled Trial
N = 18 88/100 PMID 35543701 ↗
Can This Approach Help? Inside the Latest Research on Liraglutide Effects in irregular heartbeat (AFib) (LEAF)

Whereas adding liraglutide to RFM in obese patients with AF did not produce significant differences in early weight loss or LAEAT reduction, improved freedom from AF/atrial flutter was noted.

JACC. Clinical electrophysiology • 2026-09-15 • Randomized Controlled Trial
N = 28 82/100 PMID 42159524 ↗
Can This Approach Help? Inside the Latest Research on Effect of atorvastatin vs. rosuvastatin on cardiac sympathetic nerve activity in

Lipophilic atorvastatin but not hydrophilic rosuvastatin improves cardiac sympathetic nerve activity in CHF patients with DCM.

Circulation journal : official journal of the Japanese Circulation Society • 2011-01-15 • Randomized Controlled Trial
N = 32 82/100 PMID 21737951 ↗
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Dilated cardiomyopathy Patient Community & “People Like Me” Threads

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