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Bacterial, Viral & Fungal Infections • ICD-10-CM B37.4

E. coli Infections

Also known as: Escherichia coli

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM B37.4 • 8 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

E. coli Infections Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is E. coli Infections?

E. coli is the name of a type of bacteria that lives in your intestines. Most types of E. coli are harmless. However, some types can make you sick and cause diarrhea . One type causes travelers' diarrhea. The worst type of E. coli causes bloody diarrhea, and can sometimes cause kidney failure and even death. These problems are most likely to occur in children and in adults with weak immune systems. You can get E. coli infections by eating foods containing the bacteria. Symptoms of infection include: Nausea or vomiting Severe abdominal cramps Watery or very bloody diarrhea Fatigue Fever To help avoid food poisoning and prevent infection, handle food safely .

Pathophysiology, Underlying Causes & Clinical Presentation

Biological expression of E. coli Infections (B37.4, Infections & Antivirals) reflects pathogen-associated molecular pattern in E. coli Infections (B37.4: (PAMP) innate immune). Cross-referenced with NIH MeSH (Escherichia coli Infections), longitudinal control is benchmarked via Complete Blood Count in E. coli Infections (B37.4: (WBC & Differential)).

Common Symptoms & Clinical Signs

  • • Nausea or vomiting
  • • Severe abdominal cramps
  • • Presentation of E. coli Infections (B37.4): acute fever, chills, in E. coli Infections (B37.4: malaise, and myalgias)
  • • Secondary E. coli Infections clinical sign: sore throat, productive in E. coli Infections (B37.4: cough, sinus/ear pain,)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

E. coli Infections Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code B37.4 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Bacterial, Viral & Fungal Infections NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Complete Blood Count in E. coli Infections (B37.4: (WBC & Differential)) WBC 4.0 – 10.0 x10^3/uL (B37.4) Clinical Reference Target Range
Diagnostic / Lab Marker: C-Reactive Protein / in E. coli Infections (B37.4: Procalcitonin) Resolution to baseline (B37.4) Clinical Reference Target Range
Diagnostic / Lab Marker: Targeted PCR / in E. coli Infections (B37.4: Culture & Sensitivity) Pathogen clearance / negative test (B37.4) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for E. coli Infections

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Treatment selection for E. coli Infections depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (E. coli Infections)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Olgotrelvir as a Single-Agent Treatment of Nonhospitalized Patients with: What a 1,212-Participant Study Found

Olgotrelvir as a single-agent treatment significantly improved symptom recovery.

NEJM evidence • 2024-06-15 • Phase III Randomized Trial
N = 1,212 96/100 PMID 38804790 ↗
New Insights on Benefits and safety of Tofacitinib in Ulcerative Colitis Based on Prior Tumor: What a 1,139-Participant Study Found

Tofacitinib was efficacious in patients with UC regardless of prior TNFi failure status.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association • 2022-03-15 • Phase III Randomized Trial
N = 1,139 96/100 PMID 33684552 ↗
Check Your Medicine Cabinet: Family Farmstead Dairy Announces Recall of Raw Mild Cheddar Cheese Due to Potential E. c

WORCESTER, NY, October 15, 2026 - Family Farmstead Dairy of Worcester, NY is recalling specific lot of cheddar cheese because it may be contaminated with Escherichia coli O157:H7 bacteria (E. Coli O157:H7). E. coli O157:H7 causes a diarrheal illness often with

FDA Drug Recalls • 2026-10-15 • FDA Recall
Multi-cohort 95/100 PMID FDA_RECALLS-2412744266 ↗
New Insights on Glycolipid and Hormonal Profiles in Young Men with Early-Onset Androgenetic hair: What a 1,009-Participant Study Found

The acknowledgement of this syndrome would be of importance to prevent the long-term consequences on health in the affected men.

Scientific reports • 2017-08-10 • Meta-Analysis
N = 1,009 94/100 PMID 28798373 ↗
New Insights on Long-term safety and real-world benefits of filgotinib for the treatment of: What a 250-Participant Study Found

Filgotinib induced and maintained symptomatic full symptom relief and improved HRQoL over 4 years.

Alimentary pharmacology & therapeutics • 2024-09-15 • Phase III Randomized Trial
N = 250 93/100 PMID 39086130 ↗
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