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Bacterial, Viral & Fungal Infections • ICD-10-CM A69.20

Erythema migrans

Also known as: Erythema, Erythematous, Inflamed, Inflammation

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM A69.20 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Erythema migrans Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Erythema migrans?

Under Bacterial, Viral & Fungal Infections diagnostic criteria (A69.20), workup for Erythema migrans (also termed Erythema or Erythematous) integrates bacterial/fungal culture with in Erythema migrans (A69.20: antimicrobial susceptibility testing) with evidence-graded therapy tailored to Targeted PCR / in Erythema migrans (A69.20: Culture & Sensitivity) response.

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Erythema migrans (code A69.20) is cytokine pyrogen release [Erythema migrans A69.20], which Bacterial, Viral & Fungal Infections clinicians address while surveilling Targeted PCR / in Erythema migrans (A69.20: Culture & Sensitivity) (Pathogen clearance / negative test (A69.20)).

Common Symptoms & Clinical Signs

  • • Presentation of Erythema migrans (A69.20): painful vesicular rash in Erythema migrans (A69.20: in a dermatomal)
  • • Secondary Erythema migrans clinical sign: regional lymph node in Erythema migrans (A69.20: tenderness or acute)
  • • Symptom flares in Erythema migrans correlating with Targeted PCR / in Erythema migrans (A69.20: Culture & Sensitivity) deviation outside Pathogen clearance / negative test (A69.20)
  • • Functional infections & antivirals impact requiring bacterial/fungal culture with in Erythema migrans (A69.20: antimicrobial susceptibility testing) evaluation (A69.20)

Erythema migrans Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code A69.20 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Bacterial, Viral & Fungal Infections NLM Clinical Tables
Diagnostic / Lab Marker: Targeted PCR / in Erythema migrans (A69.20: Culture & Sensitivity) Pathogen clearance / negative test (A69.20) Clinical Reference Target Range
Diagnostic / Lab Marker: Complete Blood Count in Erythema migrans (A69.20: (WBC & Differential)) WBC 4.0 – 10.0 x10^3/uL (A69.20) Clinical Reference Target Range
Diagnostic / Lab Marker: C-Reactive Protein / in Erythema migrans (A69.20: Procalcitonin) Resolution to baseline (A69.20) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Erythema migrans)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Safety profile of baricitinib in patients with systemic lupus erythematosus: an: What a 1,655-Participant Study Found

The results of this integrated safety analysis in patients with SLE are not substantially different to the established safety profile of baricitinib.

RMD open • 2023-08-15 • Phase III Randomized Trial
N = 1,655 96/100 PMID 37604638 ↗
New Insights on Anifrolumab reduces flare rates in patients with moderate to severe systemic: What a 366-Participant Study Found

Analyses of pooled TULIP-1 and TULIP-2 data support that anifrolumab reduces flares while permitting glucocorticoid taper in patients with SLE.

Lupus • 2021-07-15 • Phase III Randomized Trial
N = 366 93/100 PMID 33977796 ↗
New Insights on Benefits and safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus:: What a 367-Participant Study Found

Consistent with the well-established profile of intravenous anifrolumab, subcutaneous anifrolumab demonstrated significant, clinically meaningful treatment benefits when added to standard therapy, and an acceptable safety...

Arthritis & rheumatology (Hoboken, N.J.) • 2026-06-15 • Phase III Randomized Trial
N = 367 93/100 PMID 41466456 ↗
New Insights on Sub-setting systemic lupus erythematosus by combined molecular phenotypes defines: What a 1,747-Participant Study Found

Combinatorial analysis of four molecular biomarkers revealed subsets of SLE patients that discriminated by disease manifestations, concomitant medication use, geography, time to severe flare and SRI-4 response.

Rheumatology (Oxford, England) • 2021-11-03 • Phase III Randomized Trial
N = 1,747 90/100 PMID 33580248 ↗
Can This Approach Help? Inside the Latest Research on Disease activity and glucocorticoid tapering patterns in Japanese patients with

In the Japanese subpopulation of the TULIP-2 trial, anifrolumab resulted in improvements in disease activity to those reported for the overall population, suggesting a beneficial effect for disease control.

Modern rheumatology • 2025-04-08 • Phase III Randomized Trial
N = 24 88/100 PMID 39801286 ↗
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