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High Blood Pressure & Vascular Health • ICD-10-CM I73.81

Erythromelalgia

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM I73.81 • 7 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Erythromelalgia Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Erythromelalgia?

Recognized across U.S. clinical coding as I73.81 (Blood Pressure), Erythromelalgia is evaluated via duplex vascular ultrasonography [Erythromelalgia I73.81] to align day-to-day symptom relief with long-term physiological stability.

Pathophysiology, Underlying Causes & Clinical Presentation

Pathophysiologically, Erythromelalgia (ICD-10 I73.81) is driven by elevated systemic vascular in Erythromelalgia (I73.81: resistance); specialists in High Blood Pressure & Vascular Health monitor Home Seated Blood in Erythromelalgia (I73.81: Pressure) to gauge tissue recovery.

Common Symptoms & Clinical Signs

  • • Presentation of Erythromelalgia (I73.81): calf cramping or in Erythromelalgia (I73.81: claudication triggered by)
  • • Secondary Erythromelalgia clinical sign: localized extremity swelling, in Erythromelalgia (I73.81: warmth, or venous)
  • • Symptom flares in Erythromelalgia correlating with Urine Albumin-to-Creatinine Ratio [Erythromelalgia I73.81] deviation outside < 15 mg/g (I73.81)
  • • Functional blood pressure impact requiring duplex vascular ultrasonography [Erythromelalgia I73.81] evaluation (I73.81)

Erythromelalgia Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code I73.81 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub High Blood Pressure & Vascular Health NLM Clinical Tables
Diagnostic / Lab Marker: Urine Albumin-to-Creatinine Ratio [Erythromelalgia I73.81] < 15 mg/g (I73.81) Clinical Reference Target Range
Diagnostic / Lab Marker: Home Seated Blood in Erythromelalgia (I73.81: Pressure) < 120/75 mmHg (I73.81) Clinical Reference Target Range
Diagnostic / Lab Marker: Ankle-Brachial Index (ABI) [Erythromelalgia I73.81] 1.00 – 1.30 (I73.81) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Erythromelalgia

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Treatment selection for Erythromelalgia depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Erythromelalgia)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on A randomized, gold-standard blind study to evaluate the real-world benefits and: What a 324-Participant Study Found

In Asian patients with high blood pressure, T80/A5 single-pill combination provided improved BP reduction after 8 weeks' treatment compared with A5 single-drug treatment.

The Journal of international medical research • 2014-02-15 • Phase III Randomized Trial
N = 324 93/100 PMID 24391142 ↗
What the Latest Evidence Really Says About Comparative effectiveness and safety of statins as a class and of specific

All statins showed statistically significant risk reduction of CVD and all-cause mortality in primary prevention populations while increasing the risk for some harm risks.

American heart journal • 2019-04-15 • Meta-Analysis
Multi-cohort 92/100 PMID 30716508 ↗
Can This Approach Help? Inside the Latest Research on Effect of Liraglutide on heart and blood vessel Function and Myocardial Tissue

Liraglutide (n = 22) compared with placebo (n = 25) did not change Edec (+0.2 mL/s 2 × 10 -3 (-0.3;0.6)), E/A (-0.09 (-0.23;0.05)), E/Ea (+0.1 (-1.2;1.3)) and ejection fraction (0% (-3;2)), but decreased stroke volume (-9 mL...

Journal of magnetic resonance imaging : JMRI • 2020-06-15 • Randomized Controlled Trial
N = 22 88/100 PMID 31799782 ↗
Can This Approach Help? Inside the Latest Research on Combined 17β-estradiol and progesterone on weight and blood pressure in

Twelve-month use of E2/P4 had no clinically meaningful impact on weight or BP in postmenopausal women of the REPLENISH study.

Menopause (New York, N.Y.) • 2020-09-14 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 32932401 ↗
Can This Approach Help? Inside the Latest Research on How the body absorbs the medicine of oral doses of telmisartan and nisoldipine,

The results of this study strongly suggest that concomitant treatment with nisoldipine enhances telmisartan bioavailability in hypertensive individuals.

Journal of clinical pharmacology • 2007-03-15 • Randomized Controlled Trial
N = 37 82/100 PMID 17322141 ↗
Zero-PHI Patient Support & Cohort Discussions

Erythromelalgia Patient Community & “People Like Me” Threads

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