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Heart & Cardiovascular Disease • ICD-10-CM I42.01

Familial-genetic dilated cardiomyopathy

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM I42.01 • 7 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Familial-genetic dilated cardiomyopathy Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Familial-genetic dilated cardiomyopathy?

For patients presenting with Familial-genetic dilated cardiomyopathy (ICD-10-CM I42.01), Heart & Cardiovascular Disease protocols prioritize ambulatory rhythm monitoring [Familial-genetic dilated cardiomyopathy I42.01] paired with baseline and interval NT-proBNP [Familial-genetic dilated cardiomyopathy I42.01] assessment.

Pathophysiology, Underlying Causes & Clinical Presentation

In Familial-genetic dilated cardiomyopathy (I42.01), physiological disruption stems from myocardial oxygen supply-demand in Familial-genetic dilated cardiomyopathy (I42.01: mismatch), informing Heart & Cardiovascular Disease protocols that track High-Sensitivity Troponin I [Familial-genetic dilated cardiomyopathy I42.01] (< 14 ng/L (I42.01)).

Common Symptoms & Clinical Signs

  • • Presentation of Familial-genetic dilated cardiomyopathy (I42.01): unexplained lower-extremity ankle in Familial-genetic dilated cardiomyopathy (I42.01: edema or rapid)
  • • Secondary Familial-genetic dilated cardiomyopathy clinical sign: reduced exercise tolerance in Familial-genetic dilated cardiomyopathy (I42.01: and premature cardiovascular)
  • • Symptom flares in Familial-genetic dilated cardiomyopathy correlating with NT-proBNP [Familial-genetic dilated cardiomyopathy I42.01] deviation outside < 100 pg/mL (I42.01)
  • • Functional heart & vascular impact requiring ambulatory rhythm monitoring [Familial-genetic dilated cardiomyopathy I42.01] evaluation (I42.01)

Familial-genetic dilated cardiomyopathy Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code I42.01 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Heart & Cardiovascular Disease NLM Clinical Tables
Diagnostic / Lab Marker: NT-proBNP [Familial-genetic dilated cardiomyopathy I42.01] < 100 pg/mL (I42.01) Clinical Reference Target Range
Diagnostic / Lab Marker: High-Sensitivity Troponin I [Familial-genetic dilated cardiomyopathy I42.01] < 14 ng/L (I42.01) Clinical Reference Target Range
Diagnostic / Lab Marker: Apolipoprotein B (ApoB) [Familial-genetic dilated cardiomyopathy I42.01] < 70 mg/dL (I42.01) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Familial-genetic dilated cardiomyopathy

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Treatment selection for Familial-genetic dilated cardiomyopathy depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Familial-genetic dilated cardiomyopathy)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Long-Term safety and real-world benefits of Bempedoic Acid in Patients With: What a 1,462-Participant Study Found

Bempedoic acid was generally well tolerated and demonstrated sustained efficacy with up to 2.5 years of continuous treatment.

The American journal of cardiology • 2022-07-01 • Phase III Randomized Trial
N = 1,462 96/100 PMID 35483979 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of ezetimibe coadministered with atorvastatin or simvastatin

Ezetimibe coadministered with atorvastatin or simvastatin in patients with HoFH produced clinically important LDL-C reductions compared with best current therapy.

Circulation • 2002-05-28 • Randomized Controlled Trial
N = 25 88/100 PMID 12034651 ↗
Rosuvastatin vs. Atorvastatin: Which Works Better for Heterozygous familial high cholesterol?

Both treatments were well tolerated.

The American journal of cardiology • 2003-12-01 • Randomized Controlled Trial
N = 187 88/100 PMID 14636905 ↗
Can This Approach Help? Inside the Latest Research on Atorvastatin: an effective lipid-modifying agent in familial high

One subject withdrew for personal reasons.

Arteriosclerosis, thrombosis, and vascular biology • 1997-08-15 • Randomized Controlled Trial
N = 22 88/100 PMID 9301631 ↗
Can This Approach Help? Inside the Latest Research on A dose-titration and comparative study of rosuvastatin and atorvastatin in

All treatments were well tolerated.

Atherosclerosis • 2008-03-15 • Randomized Controlled Trial
N = 21 88/100 PMID 17727860 ↗
Zero-PHI Patient Support & Cohort Discussions

Familial-genetic dilated cardiomyopathy Patient Community & “People Like Me” Threads

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