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Fertility, Pregnancy & Postpartum Care • ICD-10-CM N97.9

Female Infertility

Also known as: Hydrosalpinx

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM N97.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Female Infertility Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Female Infertility?

Infertility means not being able to get pregnant after at least one year of trying (or 6 months if the woman is over age 35). If a woman keeps having miscarriages , it is also called infertility. Female infertility can result from age, physical problems, hormone problems, and lifestyle or environmental factors. Most cases of infertility in women result from problems with producing eggs. In primary ovarian insufficiency , the ovaries stop functioning before natural menopause. In polycystic ovary syndrome (PCOS), the ovaries may not release an egg regularly or they may not release a healthy egg. About a third of the time, infertility is because of a problem with the woman.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in fertility & pregnancy, Female Infertility (N97.9) involves micronutrient demand surge [Female Infertility N97.9]. Cross-referenced with NIH MeSH (Infertility, Female), progression correlates with shifts in Prenatal TSH, Ferritin in Female Infertility (N97.9: & Glucose Screen) (Trimester-specific clinical range (N97.9)).

Common Symptoms & Clinical Signs

  • • Presentation of Female Infertility (N97.9): irregular luteal phase in Female Infertility (N97.9: timing, anovulatory cycles,)
  • • Secondary Female Infertility clinical sign: gestational blood pressure in Female Infertility (N97.9: elevation, sudden hand/facial)
  • • Symptom flares in Female Infertility correlating with Prenatal TSH, Ferritin in Female Infertility (N97.9: & Glucose Screen) deviation outside Trimester-specific clinical range (N97.9)
  • • Functional fertility & pregnancy impact requiring semen analysis [Female Infertility N97.9] evaluation (N97.9)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Female Infertility Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code N97.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Fertility, Pregnancy & Postpartum Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Prenatal TSH, Ferritin in Female Infertility (N97.9: & Glucose Screen) Trimester-specific clinical range (N97.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Anti-Mullerian Hormone (AMH) in Female Infertility (N97.9: & Day-3 FSH) Age-contextual ovarian reserve (N97.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Maternal Blood Pressure in Female Infertility (N97.9: & Urine Protein) BP < 120/80 mmHg; negative proteinuria (N97.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Female Infertility

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Glydo- Lidocaine Hydrochloride Jelly Glydo- Lidocaine Hydrochloride Jelly Generic • RxCUI 1011852 Amide Local Anesthetic 86% $0.5046 $ 28.94 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Female Infertility)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Interventions for female pattern hair: What a 2,349-Participant Study Found

Further direct comparison studies of minoxidil 5% applied once a day, which could improve staying on track with medication when compared to minoxidil 2% twice daily, are still required.

The Cochrane database of systematic reviews • 2012-05-16 • Meta-Analysis
N = 2,349 99/100 PMID 22592723 ↗
New Insights on Efficacy and Tolerability of a Novel Tretinoin 0.05% Lotion for the Once-Daily: What a 551-Participant Study Found

Conclusions: Tretinoin 0.05% lotion was significantly more effective than vehicle in achieving treatment success and reducing inflammatory and noninflammatory lesions in adult females with moderate acne, with notable...

Journal of drugs in dermatology : JDD • 2019-11-01 • Randomized Controlled Trial
N = 551 93/100 PMID 31741360 ↗
New Insights on Benefits and safety of Ponesimod Compared with Teriflunomide in Female Patients: What a 363-Participant Study Found

Conclusions: Analyses demonstrate the real-world benefits and safety of ponesimod, versus active comparator, for women with relapsing MS, supporting data-informed decision-making for women with MS.

Journal of women's health (2002) • 2024-04-15 • Phase III Randomized Trial
N = 363 93/100 PMID 38301149 ↗
New Insights on A randomized, compared against a dummy pill (placebo) trial of 5% and 2%: What a 381-Participant Study Found

In this 48-week study of 381 women with female pattern hair loss, 5% applied to the skin minoxidil was superior to placebo on each of the 3 primary efficacy end points: promoting hair growth as measured by change in nonvellus...

Journal of the American Academy of Dermatology • 2004-04-15 • Randomized Controlled Trial
N = 381 93/100 PMID 15034503 ↗
New Insights on Modeling and simulation of sexual activity daily diary data of patients with: What a 614-Participant Study Found

A modeling and simulation framework to support drug development in FSAD was developed.

Pharmaceutical research • 2006-08-15 • Randomized Controlled Trial
N = 614 93/100 PMID 16841199 ↗
Zero-PHI Patient Support & Cohort Discussions

Female Infertility Patient Community & “People Like Me” Threads

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