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Osteoporosis, Vitamin D & Bone Density • ICD-10-CM M85.08

Fibrous dysplasia (monostotic), other site

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M85.08 • 6 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Fibrous dysplasia (monostotic), other site Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Fibrous dysplasia (monostotic), other site?

Clinical triage of Fibrous dysplasia (monostotic), other site (M85.08) in Bone Density relies on dual-energy X-ray absorptiometry in Fibrous dysplasia (monostotic), other site (M85.08: (DEXA) with FRAX), guiding step-wise therapeutic adjustments toward Serum Calcium, Phosphorus in Fibrous dysplasia (monostotic), other site (M85.08: & PTH) (Ca 8.9–10.1 mg/dL; PTH 15–65 pg/mL (M85.08)).

Pathophysiology, Underlying Causes & Clinical Presentation

In Fibrous dysplasia (monostotic), other site (M85.08), physiological disruption stems from cortical porosity [Fibrous dysplasia (monostotic), other site M85.08], informing Osteoporosis, Vitamin D & Bone Density protocols that track Serum Calcium, Phosphorus in Fibrous dysplasia (monostotic), other site (M85.08: & PTH) (Ca 8.9–10.1 mg/dL; PTH 15–65 pg/mL (M85.08)).

Common Symptoms & Clinical Signs

  • • Presentation of Fibrous dysplasia (monostotic), other site (M85.08): fragility fracture of in Fibrous dysplasia (monostotic), other site (M85.08: wrist, hip, or)
  • • Secondary Fibrous dysplasia (monostotic), other site clinical sign: gradual loss of in Fibrous dysplasia (monostotic), other site (M85.08: standing height)
  • • Symptom flares in Fibrous dysplasia (monostotic), other site correlating with 25-Hydroxy Vitamin D [Fibrous dysplasia (monostotic), other site M85.08] deviation outside 40 – 65 ng/mL (M85.08)
  • • Functional bone density impact requiring dual-energy X-ray absorptiometry in Fibrous dysplasia (monostotic), other site (M85.08: (DEXA) with FRAX) evaluation (M85.08)

Fibrous dysplasia (monostotic), other site Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M85.08 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoporosis, Vitamin D & Bone Density NLM Clinical Tables
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D [Fibrous dysplasia (monostotic), other site M85.08] 40 – 65 ng/mL (M85.08) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Calcium, Phosphorus in Fibrous dysplasia (monostotic), other site (M85.08: & PTH) Ca 8.9–10.1 mg/dL; PTH 15–65 pg/mL (M85.08) Clinical Reference Target Range
Diagnostic / Lab Marker: CTX / P1NP in Fibrous dysplasia (monostotic), other site (M85.08: Bone Turnover Markers) Balanced remodeling on therapy (M85.08) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Fibrous dysplasia (monostotic), other site

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Fibrous dysplasia (monostotic), other site)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Complications of orthopedic treatment in patients diagnosed with X-linked

In average, one complication occurred per surgery and the severity of complications were substantial.

Journal of pediatric endocrinology & metabolism : JPEM • 2022-08-26 • Phase III Randomized Trial
N = 79 82/100 PMID 35700440 ↗
Can This Approach Help? Inside the Latest Research on How the body absorbs the medicine and bioequivalence of a rosuvastatin/ezetimibe

The rosuvastatin/ezetimibe (10/10 mg) FDC was bioequivalent to single agents concomitantly administered.

International journal of clinical pharmacology and therapeutics • 2018-01-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 29162214 ↗
Can This Approach Help? Inside the Latest Research on How the body absorbs the medicine and Safety of a Fixed-dose Combination of

Sixty-four healthy Korean subjects were enrolled, and 57 subjects completed the study.

Clinical therapeutics • 2017-09-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 28803122 ↗
Can This Approach Help? Inside the Latest Research on Relative bioavailability of 2 prototype fixed-dose combination formulations for

The FDC formulations demonstrated similar bioavailability to coadministered commercially available amlodipine and rosuvastatin.

Clinical pharmacology in drug development • 2016-03-15 • Randomized Controlled Trial
N = 12 82/100 PMID 27138026 ↗
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