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Osteoporosis, Vitamin D & Bone Density • ICD-10-CM M85.00

Fibrous dysplasia (monostotic), unspecified site

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M85.00 • 4 Linked .gov / PubMed Citations • Governance: Dr. Elena Vance, MD, FACE (NPI #1043218901)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Fibrous dysplasia (monostotic), unspecified site Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Fibrous dysplasia (monostotic), unspecified site?

Fibrous dysplasia (monostotic), unspecified site is an ICD-10-CM indexed diagnosis (M85.00) within Osteoporosis, Vitamin D & Bone Density. Clinical evaluation centers on secondary metabolic bone in Fibrous dysplasia (monostotic), unspecified site (M85.00: lab panel (25-OH-D) alongside serial Serum Calcium, Phosphorus in Fibrous dysplasia (monostotic), unspecified site (M85.00: & PTH) tracking (Ca 8.9–10.1 mg/dL; PTH 15–65 pg/mL (M85.00)) to guide individualized care.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Fibrous dysplasia (monostotic), unspecified site (M85.00) features uncoupled skeletal remodeling in Fibrous dysplasia (monostotic), unspecified site (M85.00: where osteoclast-mediated bone). therapeutic stabilization in bone density is verified against CTX / P1NP in Fibrous dysplasia (monostotic), unspecified site (M85.00: Bone Turnover Markers).

Common Symptoms & Clinical Signs

  • • Presentation of Fibrous dysplasia (monostotic), unspecified site (M85.00): gradual loss of in Fibrous dysplasia (monostotic), unspecified site (M85.00: standing height)
  • • Secondary Fibrous dysplasia (monostotic), unspecified site clinical sign: diffuse bone aching in Fibrous dysplasia (monostotic), unspecified site (M85.00: or muscle weakness)
  • • Symptom flares in Fibrous dysplasia (monostotic), unspecified site correlating with Serum Calcium, Phosphorus in Fibrous dysplasia (monostotic), unspecified site (M85.00: & PTH) deviation outside Ca 8.9–10.1 mg/dL; PTH 15–65 pg/mL (M85.00)
  • • Functional bone density impact requiring secondary metabolic bone in Fibrous dysplasia (monostotic), unspecified site (M85.00: lab panel (25-OH-D) evaluation (M85.00)

Fibrous dysplasia (monostotic), unspecified site Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M85.00 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Osteoporosis, Vitamin D & Bone Density NLM Clinical Tables
Diagnostic / Lab Marker: Serum Calcium, Phosphorus in Fibrous dysplasia (monostotic), unspecified site (M85.00: & PTH) Ca 8.9–10.1 mg/dL; PTH 15–65 pg/mL (M85.00) Clinical Reference Target Range
Diagnostic / Lab Marker: CTX / P1NP in Fibrous dysplasia (monostotic), unspecified site (M85.00: Bone Turnover Markers) Balanced remodeling on therapy (M85.00) Clinical Reference Target Range
Diagnostic / Lab Marker: DEXA Bone Mineral in Fibrous dysplasia (monostotic), unspecified site (M85.00: Density T-Score) > -1.0 (hip & lumbar spine) (M85.00) Clinical Reference Target Range
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Treatment selection for Fibrous dysplasia (monostotic), unspecified site depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Fibrous dysplasia (monostotic), unspecified site)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Complications of orthopedic treatment in patients diagnosed with X-linked

In average, one complication occurred per surgery and the severity of complications were substantial.

Journal of pediatric endocrinology & metabolism : JPEM • 2022-08-26 • Phase III Randomized Trial
N = 79 82/100 PMID 35700440 ↗
Can This Approach Help? Inside the Latest Research on How the body absorbs the medicine and Safety of a Fixed-dose Combination of

Sixty-four healthy Korean subjects were enrolled, and 57 subjects completed the study.

Clinical therapeutics • 2017-09-15 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 28803122 ↗
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