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Bacterial, Viral & Fungal Infections • ICD-10-CM A49.1

H1N1 Flu (Swine Flu)

Also known as: Swine flu

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM A49.1 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

H1N1 Flu (Swine Flu) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is H1N1 Flu (Swine Flu)?

Swine flu is an infection caused by a virus. It's named for a virus that pigs can get. People do not normally get swine flu, but human infections can and do happen. In 2009 a strain of swine flu called H1N1 infected many people around the world. The virus is contagious and can spread from human to human. Symptoms of swine flu in people are similar to the symptoms of regular human flu and include fever, cough, sore throat, body aches, headache, chills and fatigue. There are antiviral medicines you can take to prevent or treat swine flu. There is a vaccine available to protect against swine flu.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in H1N1 Flu (Swine Flu) (A49.1) features or latent viral in H1N1 Flu (Swine Flu) (A49.1: reactivation within sensory). Cross-referenced with NIH MeSH (Influenza A Virus, H1N1 Subtype, Influenza, Human), therapeutic stabilization in infections & antivirals is verified against Targeted PCR / in H1N1 Flu (Swine Flu) (A49.1: Culture & Sensitivity).

Common Symptoms & Clinical Signs

  • • Covering your nose and mouth with a tissue when you cough or sneeze. Throw the tissue in the trash after you use it
  • • Washing your hands often with soap and water, especially after you cough or sneeze. You can also use alcohol-based hand cleaners
  • • Presentation of H1N1 Flu (Swine Flu) (A49.1): sore throat, productive in H1N1 Flu (Swine Flu) (A49.1: cough, sinus/ear pain,)
  • • Secondary H1N1 Flu (Swine Flu) clinical sign: painful vesicular rash in H1N1 Flu (Swine Flu) (A49.1: in a dermatomal)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

H1N1 Flu (Swine Flu) Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code A49.1 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Bacterial, Viral & Fungal Infections NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: C-Reactive Protein / in H1N1 Flu (Swine Flu) (A49.1: Procalcitonin) Resolution to baseline (A49.1) Clinical Reference Target Range
Diagnostic / Lab Marker: Targeted PCR / in H1N1 Flu (Swine Flu) (A49.1: Culture & Sensitivity) Pathogen clearance / negative test (A49.1) Clinical Reference Target Range
Diagnostic / Lab Marker: Complete Blood Count in H1N1 Flu (Swine Flu) (A49.1: (WBC & Differential)) WBC 4.0 – 10.0 x10^3/uL (A49.1) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for H1N1 Flu (Swine Flu)

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Mupirocin Ointment Dermacinrx Clorhexacin • RxCUI RXN-81033032-2271 RNA Synthetase Inhibitor Antibacterial 78% $0.1366 $ 14.03 /mo
Jublia (Efinaconazole) Jublia • RxCUI RXN-B01875400 Azole Antifungal 88% $0.2900 $ 29.38 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (H1N1 Flu (Swine Flu))

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on A phase 2/3 study of S-217622 in participants with SARS-CoV-2 infection (Phase 3

In a post hoc analysis of the phase 2b study, compared with placebo, ensitrelvir demonstrated a reduced time to resolution of 5 symptoms in patients with mild-to-moderate COVID-19.

Medicine • 2023-02-22 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 36827007 ↗
Can This Approach Help? Inside the Latest Research on [Evaluation of the real-world benefits and safety of a complex antiviral drug

Raphamin promotes significant decrease, practically by a day, the duration of ARVI, including influenza.

Terapevticheskii arkhiv • 2022-01-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 36286922 ↗
Can This Approach Help? Inside the Latest Research on Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter,

In this study, the side effects occurred at a comparable rate across the four groups, with no unexpected safety findings observed.

Signal transduction and targeted therapy • 2023-01-30 • Phase III Randomized Trial
N = 167 88/100 PMID 36717539 ↗
Can This Approach Help? Inside the Latest Research on Hemagglutination Inhibition Antibody Titers as Mediators of Influenza Vaccine

HAI titers partially mediate influenza vaccine efficacy against influenza A(H1N1), A(H3N2), and B/Victoria.

The Journal of infectious diseases • 2024-07-25 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 39052734 ↗
Zero-PHI Patient Support & Cohort Discussions

H1N1 Flu (Swine Flu) Patient Community & “People Like Me” Threads

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