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Insomnia, Sleep Apnea & Sleep Health • ICD-10-CM T68.XXXA

Hypothermia

Also known as: Cold-related illness

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM T68.XXXA • 8 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Hypothermia Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Hypothermia?

Cold weather can affect your body in different ways. You can get frostbite , which is an injury to the body that is caused by freezing. Your body can also lose heat faster than you can produce it. That can cause hypothermia, or abnormally low body temperature. It can make you sleepy, confused, and clumsy. Because it happens gradually and affects your thinking, you may not realize you need help. That makes it especially dangerous. A body temperature below 95 °F (35 °C) is a medical emergency and can lead to death if not treated promptly. Anyone who spends much time outdoors in cold weather can get hypothermia.

Pathophysiology, Underlying Causes & Clinical Presentation

Mechanistic hallmarks of Hypothermia (T68.XXXA) center on sympathetic micro-arousals [Hypothermia T68.XXXA]. Cross-referenced with NIH MeSH (Hypothermia), targeted sleep disorders interventions aim to normalize Insomnia Severity Index in Hypothermia (T68.XXXA: (ISI)).

Common Symptoms & Clinical Signs

  • • Presentation of Hypothermia (T68.XXXA): unrefreshing morning waking in Hypothermia (T68.XXXA: despite adequate hours)
  • • Secondary Hypothermia clinical sign: loud habitual snoring, in Hypothermia (T68.XXXA: witnessed breathing pauses,)
  • • Symptom flares in Hypothermia correlating with Insomnia Severity Index in Hypothermia (T68.XXXA: (ISI)) deviation outside < 7 (T68.XXXA)
  • • Functional sleep disorders impact requiring iron/thyroid screening [Hypothermia T68.XXXA] evaluation (T68.XXXA)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Hypothermia Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code T68.XXXA WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Insomnia, Sleep Apnea & Sleep Health NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Insomnia Severity Index in Hypothermia (T68.XXXA: (ISI)) < 7 (T68.XXXA) Clinical Reference Target Range
Diagnostic / Lab Marker: Nocturnal Oxygen Saturation in Hypothermia (T68.XXXA: (SpO2)) >= 94% nadir > 90% (T68.XXXA) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Ferritin (Restless in Hypothermia (T68.XXXA: Legs)) > 75 ng/mL (T68.XXXA) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Hypothermia

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Calcium Chloride, Magnesium Chloride, Potassium Chloride and Sodium Chloride Cardioplegic • RxCUI RXN-03380341-1780 Blood Coagulation Factor 87% $1.6100 $ 73.71 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Hypothermia)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Association between obstructive sleep apnea and male serum: What a 1,823-Participant Study Found

Obstructive sleep apnea is inversely associated with male serum testosterone levels, independent of body mass index and age.

Andrology • 2022-02-15 • Meta-Analysis
N = 1,823 94/100 PMID 34536053 ↗
New Insights on Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate: What a 414-Participant Study Found

Adjuvant erythropoietin did not reduce the incidence of regional brain injury.

Developmental neuroscience • 2024-01-15 • Phase III Randomized Trial
N = 414 93/100 PMID 37906983 ↗
What the Latest Evidence Really Says About Efficacy of melatonin and ramelteon for the acute and long-term management of

PR melatonin and ramelteon appear efficacious compared with placebo for trouble sleeping symptoms with PR melatonin showing mostly small to medium effect sizes.

Journal of sleep research • 2023-12-15 • Meta-Analysis
Multi-cohort 92/100 PMID 37434463 ↗
New Insights on Effect of high-flow nasal cannula therapy on adults with obstructive sleep: What a 327-Participant Study Found

HFNC therapy is a promising alternative for managing OSA.

Medicine • 2025-11-28 • Meta-Analysis
N = 327 91/100 PMID 41327738 ↗
Can This Approach Help? Inside the Latest Research on Effect of liraglutide 3.0 mg in individuals with obesity and moderate or severe

As an add-on booster to diet and exercise, liraglutide 3.0 mg was generally well tolerated and produced significantly greater reductions than placebo in AHI, body weight, SBP and HbA1c in participants with obesity and...

International journal of obesity (2005) • 2016-08-15 • Randomized Controlled Trial
N = 180 88/100 PMID 27005405 ↗
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Hypothermia Patient Community & “People Like Me” Threads

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