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Liver, Gallbladder & Pancreatic Health • ICD-10-CM K86.8

Liver Transplantation

Also known as: Hepatic transplantation

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM K86.8 • 8 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Liver Transplantation Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Liver Transplantation?

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. You cannot live without a liver that works. If your liver fails, your doctor may put you on a waiting list for a liver transplant. Doctors do liver transplants when other treatment cannot keep a damaged liver working. During a liver transplantation, the surgeon removes the diseased liver and replaces it with a healthy one. Most transplant livers come from a donor who has died. Sometimes there is a living donor. This is when a healthy person donates part of his or her liver for a specific patient.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Liver Transplantation (K86.8) features or premature pancreatic in Liver Transplantation (K86.8: acinar zymogen activation). Cross-referenced with NIH MeSH (Liver Transplantation), therapeutic stabilization in liver & hepatology is verified against ALT, AST, Alkaline in Liver Transplantation (K86.8: Phosphatase & GGT).

Common Symptoms & Clinical Signs

  • • Presentation of Liver Transplantation (K86.8): epigastric pain, steatorrhea [Liver Transplantation K86.8]
  • • Secondary Liver Transplantation clinical sign: asymptomatic elevation of in Liver Transplantation (K86.8: liver transaminases)
  • • Symptom flares in Liver Transplantation correlating with Fasting Lipase & in Liver Transplantation (K86.8: Triglycerides) deviation outside Normal enzymatic baseline (K86.8)
  • • Functional liver & hepatology impact requiring biliary/pancreatic ductal imaging [Liver Transplantation K86.8] evaluation (K86.8)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Liver Transplantation Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code K86.8 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Liver, Gallbladder & Pancreatic Health NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Fasting Lipase & in Liver Transplantation (K86.8: Triglycerides) Normal enzymatic baseline (K86.8) Clinical Reference Target Range
Diagnostic / Lab Marker: ALT, AST, Alkaline in Liver Transplantation (K86.8: Phosphatase & GGT) ALT < 25 U/L (men) / < 19 U/L (women) (K86.8) Clinical Reference Target Range
Diagnostic / Lab Marker: FIB-4 Hepatic Fibrosis in Liver Transplantation (K86.8: Index) < 1.30 (K86.8) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Liver Transplantation

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Treatment selection for Liver Transplantation depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Liver Transplantation)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on GLP-1 receptor agonists on the degree of liver fibrosis and CRP in non-alcoholic: What a 2,178-Participant Study Found

This study evaluated the efficacy of GLP-1RAs in patients with NAFLD and NASH.

Primary care diabetes • 2024-06-15 • Meta-Analysis
N = 2,178 99/100 PMID 38555202 ↗
New Insights on Cenicriviroc Lacked Efficacy to Treat Liver Fibrosis in Nonalcoholic: What a 1,778-Participant Study Found

This study did not demonstrate the efficacy of CVC for treating liver fibrosis assessed by histology in adults with NASH; however, CVC was safe and well tolerated in patients with NASH and liver fibrosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association • 2024-01-15 • Phase III Randomized Trial
N = 1,778 96/100 PMID 37061109 ↗
Check Your Medicine Cabinet: Early Alert: Transcatheter Mitral Valve Delivery System Issue from Edwards Lifesciences

Potential balloon burst during inflation can lead to embolism or the need for surgery.

FDA MedWatch Safety Alerts • 2026-10-15 • FDA Safety Alert
Multi-cohort 95/100 PMID FDA_MEDWATCH-1936956490 ↗
New Insights on Eptinezumab on self-reported work productivity in adults with migraine and prior: What a 890-Participant Study Found

In adults with migraine and prior preventive treatment failure, eptinezumab 100 mg and 300 mg IV every 12 weeks improved absenteeism, presenteeism, work productivity loss, and activity impairment more than placebo.

The journal of headache and pain • 2022-12-02 • Phase III Randomized Trial
N = 890 93/100 PMID 36460983 ↗
New Insights on Resmetirom for nonalcoholic fatty liver disease: a randomized, gold-standard: What a 325-Participant Study Found

These findings demonstrate resmetirom was safe and well tolerated in adults with presumed NASH, supporting a role for further clinical development.

Nature medicine • 2023-11-15 • Phase III Randomized Trial
N = 325 93/100 PMID 37845512 ↗
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