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Eye Health, Glaucoma & Vision Disorders • ICD-10-CM H35.359

Macular degeneration - cystoid

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM H35.359 • 8 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Macular degeneration - cystoid Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Macular degeneration - cystoid?

Designated in federal medical registries as H35.359, Macular degeneration - cystoid falls under Eyes & Vision management, where AREDS2 macular nutrition [Macular degeneration - cystoid H35.359] establishes baseline severity and rules out diagnostic mimics.

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Macular degeneration - cystoid (code H35.359) is retinal pigment epithelium in Macular degeneration - cystoid (H35.359: oxidative drusen accumulation), which Eye Health, Glaucoma & Vision Disorders clinicians address while surveilling Best-Corrected Visual Acuity in Macular degeneration - cystoid (H35.359: & OCT) (Intact retinal nerve fiber & macula (H35.359)).

Common Symptoms & Clinical Signs

  • • Presentation of Macular degeneration - cystoid (H35.359): gritty burning, foreign-body in Macular degeneration - cystoid (H35.359: sensation, reflex tearing,)
  • • Secondary Macular degeneration - cystoid clinical sign: loss of peripheral in Macular degeneration - cystoid (H35.359: side vision)
  • • Symptom flares in Macular degeneration - cystoid correlating with Best-Corrected Visual Acuity in Macular degeneration - cystoid (H35.359: & OCT) deviation outside Intact retinal nerve fiber & macula (H35.359)
  • • Functional eyes & vision impact requiring AREDS2 macular nutrition [Macular degeneration - cystoid H35.359] evaluation (H35.359)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Macular degeneration - cystoid Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code H35.359 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Eye Health, Glaucoma & Vision Disorders NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Best-Corrected Visual Acuity in Macular degeneration - cystoid (H35.359: & OCT) Intact retinal nerve fiber & macula (H35.359) Clinical Reference Target Range
Diagnostic / Lab Marker: HbA1c & Systemic in Macular degeneration - cystoid (H35.359: Blood Pressure) Microvascular retinal protection (H35.359) Clinical Reference Target Range
Diagnostic / Lab Marker: Intraocular Pressure (IOP) [Macular degeneration - cystoid H35.359] 10 – 21 mmHg (individualized optic target) (H35.359) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Macular degeneration - cystoid

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Treatment selection for Macular degeneration - cystoid depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Macular degeneration - cystoid)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration: What a 4,504-Participant Study Found

Higher dietary intake of multiple nutrients, including minerals, vitamins, and carotenoids, is associated with decreased risk of progression to late AMD.

Ophthalmology • 2021-03-15 • Phase III Randomized Trial
N = 4,504 90/100 PMID 32858063 ↗
New Insights on EFFECT OF RETINAL THICKNESS VARIABILITY ON VISUAL OUTCOMES AND FLUID PERSISTENCE: What a 1,752-Participant Study Found

More stable CST was associated with better visual outcomes at the end of treatment suggesting that CST variability may provide a more reliable prognostic marker of visual outcomes than the presence of fluid alone, with the...

Retina (Philadelphia, Pa.) • 2022-03-01 • Phase III Randomized Trial
N = 1,752 90/100 PMID 34923515 ↗
New Insights on Association between screening duration and treatment outcomes in the clinical: What a 1,152-Participant Study Found

Linear regression coefficients for screening duration were not statistically significant for BCVA or CST at week 8 (BCVA: B = - 0.058, P = 0.242; CST: B = - 0.050, P = 0.908) or at week 48 (BCVA: B = - 0.015, P = 0.843; CST: B...

Scientific reports • 2026-04-02 • Phase III Randomized Trial
N = 1,152 90/100 PMID 41927600 ↗
New Insights on Subretinal Fluid Resolution and Visual Acuity in Patients with Neovascular: What a 1,097-Participant Study Found

A greater proportion of ranibizumab-treated eyes with nAMD gained/maintained visual acuity at SRF resolution.

Ophthalmology. Retina • 2022-11-15 • Phase III Randomized Trial
N = 1,097 90/100 PMID 35654363 ↗
Can This Approach Help? Inside the Latest Research on Resolution of outer retinal abnormalities in eyes with vitreomacular traction

ELM disruption, EZ disruption and/or SRF are present in a significant percentage of eyes with VMT without MH.

The British journal of ophthalmology • 2023-07-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 35288439 ↗
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