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Neurology, Stroke & Movement Disorders • ICD-10-CM G23.8

Olivopontocerebellar atrophy

Also known as: Atrophy, Atrophic, Atrophies, Wasted

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM G23.8 • 4 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Olivopontocerebellar atrophy Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Olivopontocerebellar atrophy?

For patients presenting with Olivopontocerebellar atrophy (also termed Atrophy or Atrophic) (ICD-10-CM G23.8), Neurology, Stroke & Movement Disorders protocols prioritize vascular stroke risk in Olivopontocerebellar atrophy (G23.8: stratification) paired with baseline and interval HbA1c & Blood in Olivopontocerebellar atrophy (G23.8: Pressure Neuro-Targets) assessment.

Pathophysiology, Underlying Causes & Clinical Presentation

In Olivopontocerebellar atrophy (G23.8), physiological disruption stems from or basal ganglia in Olivopontocerebellar atrophy (G23.8: dopaminergic circuit degeneration), informing Neurology, Stroke & Movement Disorders protocols that track Serum Vitamin B12 in Olivopontocerebellar atrophy (G23.8: & Methylmalonic Acid) (B12 > 500 pg/mL; MMA < 240 nmol/L (G23.8)).

Common Symptoms & Clinical Signs

  • • Presentation of Olivopontocerebellar atrophy (G23.8): numbness, paresthesia, or in Olivopontocerebellar atrophy (G23.8: visual field/speech changes)
  • • Secondary Olivopontocerebellar atrophy clinical sign: muscle stiffness, spasticity, in Olivopontocerebellar atrophy (G23.8: or fatigable neuromuscular)
  • • Symptom flares in Olivopontocerebellar atrophy correlating with HbA1c & Blood in Olivopontocerebellar atrophy (G23.8: Pressure Neuro-Targets) deviation outside BP < 120/75 mmHg; HbA1c < 5.7% (G23.8)
  • • Functional brain & neurology impact requiring vascular stroke risk in Olivopontocerebellar atrophy (G23.8: stratification) evaluation (G23.8)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Olivopontocerebellar atrophy Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code G23.8 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Neurology, Stroke & Movement Disorders NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: HbA1c & Blood in Olivopontocerebellar atrophy (G23.8: Pressure Neuro-Targets) BP < 120/75 mmHg; HbA1c < 5.7% (G23.8) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Vitamin B12 in Olivopontocerebellar atrophy (G23.8: & Methylmalonic Acid) B12 > 500 pg/mL; MMA < 240 nmol/L (G23.8) Clinical Reference Target Range
Diagnostic / Lab Marker: Carotid Duplex / in Olivopontocerebellar atrophy (G23.8: Cerebral Perfusion) No hemodynamically significant stenosis (G23.8) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Olivopontocerebellar atrophy

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Treatment selection for Olivopontocerebellar atrophy depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Olivopontocerebellar atrophy)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Glial Fibrillary Acidic Protein as a Marker of Disease in Relapsing Multiple

These data suggest that plasma GFAP is a relapse-independent metric of baseline disease severity and a predictor of treatment response in participants with RMS.

European journal of neurology • 2025-06-15 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 40462564 ↗
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