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Hair Loss, Alopecia & Scalp Conditions • ICD-10-CM L60.1

Onycholysis

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM L60.1 • 8 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Onycholysis Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Onycholysis?

Under Hair Loss, Alopecia & Scalp Conditions diagnostic criteria (L60.1), workup for Onycholysis integrates hair-pull test [Onycholysis L60.1] with evidence-graded therapy tailored to 25-Hydroxy Vitamin D in Onycholysis (L60.1: & Zinc) response.

Pathophysiology, Underlying Causes & Clinical Presentation

Onycholysis (L60.1) alters hair & scalp homeostasis through shortened anagen growth in Onycholysis (L60.1: phase); clinical remission targets Total/Free Testosterone & in Onycholysis (L60.1: DHEA-S (if androgenic)) within Age/sex physiological range (L60.1).

Common Symptoms & Clinical Signs

  • • Presentation of Onycholysis (L60.1): discrete smooth circular in Onycholysis (L60.1: patches of sudden)
  • • Secondary Onycholysis clinical sign: thickened, discolored, brittle, in Onycholysis (L60.1: or subungually lifting)
  • • Symptom flares in Onycholysis correlating with 25-Hydroxy Vitamin D in Onycholysis (L60.1: & Zinc) deviation outside 25(OH)D 45 – 70 ng/mL (L60.1)
  • • Functional hair & scalp impact requiring hair-pull test [Onycholysis L60.1] evaluation (L60.1)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Onycholysis Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code L60.1 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Hair Loss, Alopecia & Scalp Conditions NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D in Onycholysis (L60.1: & Zinc) 25(OH)D 45 – 70 ng/mL (L60.1) Clinical Reference Target Range
Diagnostic / Lab Marker: Total/Free Testosterone & in Onycholysis (L60.1: DHEA-S (if androgenic)) Age/sex physiological range (L60.1) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Ferritin [Onycholysis L60.1] 70 – 150 ng/mL (L60.1) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Onycholysis

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Treatment selection for Onycholysis depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Onycholysis)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Combination Therapy in Androgenetic hair loss: A Network Meta-Analysis of: What a 3,012-Participant Study Found

Based on the current studies, we found that the combination of Minoxidil with spironolactone, PRPF, flutamide, and finasteride may offer better treatment outcomes for patients with androgenetic hair loss.

Aesthetic plastic surgery • 2026-07-15 • Meta-Analysis
N = 3,012 99/100 PMID 42168420 ↗
What the Latest Evidence Really Says About Minoxidil for patchy hair loss areata: systematic review and

Treatment of patchy AA with 5% minoxidil proved effective, and clinically and statistically safe in studies with limited sample size; quality of evidence was moderate.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2019-09-15 • Meta-Analysis
Multi-cohort 92/100 PMID 30835901 ↗
Can This Approach Help? Inside the Latest Research on Skin-applied adenosine increases the proportion of thick hair in Caucasian men

No adverse effects due to treatment were noted during this study by dermatological evaluation.

The Journal of dermatology • 2016-05-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 26508659 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of ritlecitinib in Asian patients with hair loss areata: A

Ritlecitinib demonstrated clinical efficacy and acceptable safety over 48 weeks in Asian patients ≥12 years with AA and ≥50% hair loss.

The Journal of dermatology • 2025-04-15 • Phase III Randomized Trial
N = 33 88/100 PMID 40071721 ↗
Can This Approach Help? Inside the Latest Research on Finasteride increases anagen hair in men with androgenetic hair

These data provide direct evidence that finasteride 1 mg daily promotes the conversion of hairs into the anagen phase.

The British journal of dermatology • 2000-10-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 11069460 ↗
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Onycholysis Patient Community & “People Like Me” Threads

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