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Eye Health, Glaucoma & Vision Disorders • ICD-10-CM H47.10

Optic disc swelling (papilledema)

Also known as: Papilledema

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM H47.10 • 7 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Optic disc swelling (papilledema) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Optic disc swelling (papilledema)?

Physicians managing Optic disc swelling (papilledema) (also termed Papilledema) (H47.10; Eye Health, Glaucoma & Vision Disorders) utilize slit-lamp biomicroscopy [Optic disc swelling (papilledema) H47.10] and objective HbA1c & Systemic in Optic disc swelling (papilledema) (H47.10: Blood Pressure) targets (Microvascular retinal protection (H47.10)) to prevent progression and functional morbidity.

Pathophysiology, Underlying Causes & Clinical Presentation

Biological expression of Optic disc swelling (papilledema) (H47.10, Eyes & Vision) reflects crystalline lens protein in Optic disc swelling (papilledema) (H47.10: opacification). longitudinal control is benchmarked via HbA1c & Systemic in Optic disc swelling (papilledema) (H47.10: Blood Pressure).

Common Symptoms & Clinical Signs

  • • Presentation of Optic disc swelling (papilledema) (H47.10): gradual blurring, glare/halos in Optic disc swelling (papilledema) (H47.10: around nighttime headlights,)
  • • Secondary Optic disc swelling (papilledema) clinical sign: gritty burning, foreign-body in Optic disc swelling (papilledema) (H47.10: sensation, reflex tearing,)
  • • Symptom flares in Optic disc swelling (papilledema) correlating with HbA1c & Systemic in Optic disc swelling (papilledema) (H47.10: Blood Pressure) deviation outside Microvascular retinal protection (H47.10)
  • • Functional eyes & vision impact requiring slit-lamp biomicroscopy [Optic disc swelling (papilledema) H47.10] evaluation (H47.10)

Optic disc swelling (papilledema) Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code H47.10 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Eye Health, Glaucoma & Vision Disorders NLM Clinical Tables
Diagnostic / Lab Marker: HbA1c & Systemic in Optic disc swelling (papilledema) (H47.10: Blood Pressure) Microvascular retinal protection (H47.10) Clinical Reference Target Range
Diagnostic / Lab Marker: Intraocular Pressure (IOP) [Optic disc swelling (papilledema) H47.10] 10 – 21 mmHg (individualized optic target) (H47.10) Clinical Reference Target Range
Diagnostic / Lab Marker: Best-Corrected Visual Acuity in Optic disc swelling (papilledema) (H47.10: & OCT) Intact retinal nerve fiber & macula (H47.10) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Optic disc swelling (papilledema)

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Pro Numb Sensitive Skin (Numbing Spray) Pro Numb Sensitive Skin • RxCUI RXN-B83389112 Amide Local Anesthetic 74% $2.1600 $ 164.02 /mo
Chlorhexidine Gluconate Dyna-Hex 4, Scrub-Stat • RxCUI 834127 Decreased Cell Wall Integrity 82% $0.0074 $ 17.53 /mo
Dermveda Ultra Dark Spot Remedy Serum (Glycyrrhiza Glabra, Curcuma Longa) Dermveda Ultra Dark Spot Remedy Serum • RxCUI RXN-B83819609 Non-Standardized Food Allergenic Extract 85% $1.3600 $ 106.42 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Optic disc swelling (papilledema))

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Benefits and safety of HSK3486 for Anesthesia/Sedation in Patients Undergoing: What a 267-Participant Study Found

HSK3486 exhibited non-inferiority anesthesia/sedation compared to propofol in patients undergoing fiberoptic bronchoscopy, and had a good safety profile with a lower incidence of pain on injection.

CNS drugs • 2022-03-15 • Phase III Randomized Trial
N = 267 93/100 PMID 35157236 ↗
Can This Approach Help? Inside the Latest Research on Exploring steroid tapering in patients with neuromyelitis optica spectrum

During the OLE of SAkuraSky, 16 patients tapered steroids and the ARR did not increase from the DB period.

Multiple sclerosis and related disorders • 2022-05-15 • Phase III Randomized Trial
N = 16 88/100 PMID 35537314 ↗
Can This Approach Help? Inside the Latest Research on Intravenous immunoglobulin treatment for steroid-resistant optic neuritis: a

Our results suggest that intravenous immunoglobulin could be a safe and efficacious therapeutic option for prompt treatment of steroid-resistant acute ON.

Japanese journal of ophthalmology • 2021-01-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 33469728 ↗
New Insights on Longitudinal Prediction of Retinal Sensitivity Based on Disease Progression: What a 406-Participant Study Found

Two exploratory endpoints were developed, namely quantification of EZ thickness and loss, and localized RS within high-risk OCT areas.

Investigative ophthalmology & visual science • 2026-09-01 • Phase III Randomized Trial
N = 406 87/100 PMID 42742213 ↗
New Insights on Phenomapping-derived selection of fractional flow reserve or optical coherence: What a 405-Participant Study Found

Compared with a functional assessment, an OCT-based approach reduces revascularisation in patients with STEMI/NSTEMI, while FFR proved non-inferior for patients with stable angina.

Open heart • 2025-09-17 • Phase III Randomized Trial
N = 405 87/100 PMID 40967674 ↗
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