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High Blood Pressure & Vascular Health • ICD-10-CM I73.9

Peripheral vascular disease

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM I73.9 • 7 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
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Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Peripheral vascular disease Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Peripheral vascular disease?

Physicians managing Peripheral vascular disease (I73.9; High Blood Pressure & Vascular Health) utilize renal-electrolyte panels [Peripheral vascular disease I73.9] and objective Home Seated Blood in Peripheral vascular disease (I73.9: Pressure) targets (< 120/75 mmHg (I73.9)) to prevent progression and functional morbidity.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Peripheral vascular disease (I73.9) features venous valve incompetence [Peripheral vascular disease I73.9]. therapeutic stabilization in blood pressure is verified against Ankle-Brachial Index (ABI) [Peripheral vascular disease I73.9].

Common Symptoms & Clinical Signs

  • • Presentation of Peripheral vascular disease (I73.9): cold distal extremities in Peripheral vascular disease (I73.9: or diminished peripheral)
  • • Secondary Peripheral vascular disease clinical sign: persistently elevated home in Peripheral vascular disease (I73.9: or clinic blood)
  • • Symptom flares in Peripheral vascular disease correlating with Home Seated Blood in Peripheral vascular disease (I73.9: Pressure) deviation outside < 120/75 mmHg (I73.9)
  • • Functional blood pressure impact requiring renal-electrolyte panels [Peripheral vascular disease I73.9] evaluation (I73.9)

Peripheral vascular disease Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code I73.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub High Blood Pressure & Vascular Health NLM Clinical Tables
Diagnostic / Lab Marker: Home Seated Blood in Peripheral vascular disease (I73.9: Pressure) < 120/75 mmHg (I73.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Ankle-Brachial Index (ABI) [Peripheral vascular disease I73.9] 1.00 – 1.30 (I73.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Serum Creatinine & in Peripheral vascular disease (I73.9: Potassium) K+ 4.0 – 4.8 mEq/L (I73.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Peripheral vascular disease

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Treatment selection for Peripheral vascular disease depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Peripheral vascular disease)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in: What a 1,251-Participant Study Found

Mind-body exercise is beneficial for improving global cognitive function, verbal fluency, executive function, episodic memory, and short-term memory in older adults with MCI; however, evidence remains insufficient regarding...

Geriatrics & gerontology international • 2026-11-15 • Meta-Analysis
N = 1,251 94/100 PMID 42951347 ↗
New Insights on Calmangafodipir for Prevention of Oxaliplatin-Induced Peripheral Neuropathy: Two: What a 301-Participant Study Found

The POLAR clinical studies failed to meet their primary endpoint.

JNCI cancer spectrum • 2022-11-01 • Phase III Randomized Trial
N = 301 93/100 PMID 36308441 ↗
New Insights on Semaglutide and walking capacity in people with symptomatic peripheral artery: What a 396-Participant Study Found

Semaglutide increased walking distance in patients with symptomatic peripheral artery disease and type 2 diabetes.

Lancet (London, England) • 2025-05-03 • Phase III Randomized Trial
N = 396 93/100 PMID 40169145 ↗
New Insights on Quality of life outcomes with a new sustained‑release pregabalin in a phase 3: What a 296-Participant Study Found

Once-daily SR pregabalin (YHD1119) achieved QoL outcomes comparable to twice-daily IR pregabalin across general health status, sleep interference, and global impressions over 12 weeks.

Current medical research and opinion • 2026-07-15 • Phase III Randomized Trial
N = 296 93/100 PMID 42622433 ↗
New Insights on Characteristics and long-term follow-up of participants with peripheral arterial: What a 830-Participant Study Found

Neither amlodipine nor lisinopril showed superiority over chlorthalidone in reducing clinically advanced PAD risk.

Journal of general internal medicine • 2014-11-15 • Randomized Controlled Trial
N = 830 93/100 PMID 25002161 ↗
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Peripheral vascular disease Patient Community & “People Like Me” Threads

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