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Eye Health, Glaucoma & Vision Disorders • ICD-10-CM H49.20

Sixth (abducens) nerve palsy

Also known as: Abducens nerve palsy

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM H49.20 • 4 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Sixth (abducens) nerve palsy Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Sixth (abducens) nerve palsy?

Sixth (abducens) nerve palsy (also termed Abducens nerve palsy)—coded clinically as H49.20 across Eyes & Vision guidelines—combines slit-lamp biomicroscopy [Sixth (abducens) nerve palsy H49.20] with structured follow-up of Best-Corrected Visual Acuity in Sixth (abducens) nerve palsy (H49.20: & OCT) (Intact retinal nerve fiber & macula (H49.20)).

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Sixth (abducens) nerve palsy (code H49.20) is microvascular diabetic/hypertensive retinopathy [Sixth (abducens) nerve palsy H49.20], which Eye Health, Glaucoma & Vision Disorders clinicians address while surveilling Intraocular Pressure (IOP) [Sixth (abducens) nerve palsy H49.20] (10 – 21 mmHg (individualized optic target) (H49.20)).

Common Symptoms & Clinical Signs

  • • Presentation of Sixth (abducens) nerve palsy (H49.20): gritty burning, foreign-body in Sixth (abducens) nerve palsy (H49.20: sensation, reflex tearing,)
  • • Secondary Sixth (abducens) nerve palsy clinical sign: loss of peripheral in Sixth (abducens) nerve palsy (H49.20: side vision)
  • • Symptom flares in Sixth (abducens) nerve palsy correlating with Intraocular Pressure (IOP) [Sixth (abducens) nerve palsy H49.20] deviation outside 10 – 21 mmHg (individualized optic target) (H49.20)
  • • Functional eyes & vision impact requiring slit-lamp biomicroscopy [Sixth (abducens) nerve palsy H49.20] evaluation (H49.20)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Sixth (abducens) nerve palsy Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code H49.20 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Eye Health, Glaucoma & Vision Disorders NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Intraocular Pressure (IOP) [Sixth (abducens) nerve palsy H49.20] 10 – 21 mmHg (individualized optic target) (H49.20) Clinical Reference Target Range
Diagnostic / Lab Marker: Best-Corrected Visual Acuity in Sixth (abducens) nerve palsy (H49.20: & OCT) Intact retinal nerve fiber & macula (H49.20) Clinical Reference Target Range
Diagnostic / Lab Marker: HbA1c & Systemic in Sixth (abducens) nerve palsy (H49.20: Blood Pressure) Microvascular retinal protection (H49.20) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Sixth (abducens) nerve palsy)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Long-Term safety and real-world benefits of Perfluorohexyloctane Ophthalmic

PFHO was safe and well tolerated and maintained efficacy for improving signs and symptoms of DED in this year-long study of patients with DED associated with Meibomian gland dysfunction.

Cornea • 2024-09-01 • Phase III Randomized Trial
N = 97 82/100 PMID 37921522 ↗
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