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Prostate (BPH), Bladder & Urinary Tract • ICD-10-CM N43.40

Spermatocele

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM N43.40 • 6 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Spermatocele Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Spermatocele?

Within Prostate (BPH), Bladder & Urinary Tract practice, Spermatocele (ICD-10 N43.40) is stratified through urinalysis/urine culture [Spermatocele N43.40], pairing targeted symptom control with longitudinal IPSS Urinary Symptom in Spermatocele (N43.40: Score) surveillance.

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Spermatocele (code N43.40) is alpha-1A adrenergic smooth-muscle in Spermatocele (N43.40: tone narrowing the), which Prostate (BPH), Bladder & Urinary Tract clinicians address while surveilling Total PSA & in Spermatocele (N43.40: Serum Creatinine/eGFR) (Age-specific PSA; eGFR > 75 mL/min (N43.40)).

Common Symptoms & Clinical Signs

  • • Presentation of Spermatocele (N43.40): weak, hesitant, or in Spermatocele (N43.40: intermittent urinary stream)
  • • Secondary Spermatocele clinical sign: waking two or in Spermatocele (N43.40: more times nightly)
  • • Symptom flares in Spermatocele correlating with Total PSA & in Spermatocele (N43.40: Serum Creatinine/eGFR) deviation outside Age-specific PSA; eGFR > 75 mL/min (N43.40)
  • • Functional urology & prostate impact requiring urinalysis/urine culture [Spermatocele N43.40] evaluation (N43.40)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Spermatocele Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code N43.40 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Prostate (BPH), Bladder & Urinary Tract NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Total PSA & in Spermatocele (N43.40: Serum Creatinine/eGFR) Age-specific PSA; eGFR > 75 mL/min (N43.40) Clinical Reference Target Range
Diagnostic / Lab Marker: IPSS Urinary Symptom in Spermatocele (N43.40: Score) 0 – 7 (mild symptoms) (N43.40) Clinical Reference Target Range
Diagnostic / Lab Marker: Urinalysis & Post-Void in Spermatocele (N43.40: Residual (PVR)) Negative leukocyte/nitrite; PVR < 50 mL (N43.40) Clinical Reference Target Range
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FDA-Monographed Medications & Public Cash Price Reference for Spermatocele

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Treatment selection for Spermatocele depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Spermatocele)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Tadalafil administered once daily for lower urinary tract symptoms secondary to

• In men with BPH-LUTS, 5 mg of tadalafil once daily during 1 year of treatment was well tolerated and efficacy changes were maintained.

BJU international • 2011-04-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 21244606 ↗
New Insights on Avelumab first-line maintenance for advanced urothelial carcinoma: long-term: What a 350-Participant Study Found

These exploratory analyses support the efficacy and tolerability of avelumab 1L maintenance in patients aged ≥65 years with la/mUC that has not progressed following chemotherapy, suggesting that older age should not solely.

ESMO open • 2025-04-15 • Phase III Randomized Trial
N = 350 87/100 PMID 40107155 ↗
Can This Approach Help? Inside the Latest Research on Bladder Adjuvant Radiotherapy: Phase III Multicenter Randomized Controlled Trial

Adjuvant pelvic IMRT after radical cystectomy and perioperative chemotherapy suggests an improvement in locoregional control in patients with high risk urothelial MIBC with no additional severe toxicity.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2026-07-15 • Phase III Randomized Trial
N = 153 82/100 PMID 42166701 ↗
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Spermatocele Patient Community & “People Like Me” Threads

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