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Back Pain, Spine & Musculoskeletal Injuries • ICD-10-CM M48.07

Spinal stenosis, lumbosacral region

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM M48.07 • 7 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Spinal stenosis, lumbosacral region Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Spinal stenosis, lumbosacral region?

Under Back Pain, Spine & Musculoskeletal Injuries diagnostic criteria (M48.07), workup for Spinal stenosis, lumbosacral region integrates progressive core/posterior-chain physical in Spinal stenosis, lumbosacral region (M48.07: therapy) with evidence-graded therapy tailored to Neurologic Myotome / in Spinal stenosis, lumbosacral region (M48.07: Reflex Exam) response.

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Spinal stenosis, lumbosacral region (code M48.07) is ligamentum flavum hypertrophy [Spinal stenosis, lumbosacral region M48.07], which Back Pain, Spine & Musculoskeletal Injuries clinicians address while surveilling Neurologic Myotome / in Spinal stenosis, lumbosacral region (M48.07: Reflex Exam) (5/5 symmetrical motor strength (M48.07)).

Common Symptoms & Clinical Signs

  • • Presentation of Spinal stenosis, lumbosacral region (M48.07): paraspinal muscle spasm, in Spinal stenosis, lumbosacral region (M48.07: guarded posture, or)
  • • Secondary Spinal stenosis, lumbosacral region clinical sign: neurogenic leg heaviness in Spinal stenosis, lumbosacral region (M48.07: while walking upright)
  • • Symptom flares in Spinal stenosis, lumbosacral region correlating with Neurologic Myotome / in Spinal stenosis, lumbosacral region (M48.07: Reflex Exam) deviation outside 5/5 symmetrical motor strength (M48.07)
  • • Functional back, spine & ortho impact requiring progressive core/posterior-chain physical in Spinal stenosis, lumbosacral region (M48.07: therapy) evaluation (M48.07)

Spinal stenosis, lumbosacral region Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code M48.07 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Back Pain, Spine & Musculoskeletal Injuries NLM Clinical Tables
Diagnostic / Lab Marker: Neurologic Myotome / in Spinal stenosis, lumbosacral region (M48.07: Reflex Exam) 5/5 symmetrical motor strength (M48.07) Clinical Reference Target Range
Diagnostic / Lab Marker: Oswestry / Functional in Spinal stenosis, lumbosacral region (M48.07: Mobility Score) Minimal functional limitation (M48.07) Clinical Reference Target Range
Diagnostic / Lab Marker: 25-Hydroxy Vitamin D [Spinal stenosis, lumbosacral region M48.07] 40 – 65 ng/mL (M48.07) Clinical Reference Target Range
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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Spinal stenosis, lumbosacral region)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Sildenafil effects on sexual and heart and blood vessel responses in women with

Findings suggest that sildenafil may partially reverse the sexual dysfunction commonly associated with SCI in women.

Urology • 2000-06-15 • Randomized Controlled Trial
Multi-cohort 88/100 PMID 10840082 ↗
Calmer Recovery After Surgery: How This Sedative Steadies Breathing and Heart Rate

Dexmedetomidine as an add-on booster to oxycodone PCA produced transient blood flow and heart rate effects without differences in slow heart rate or in the measured breathing variables.

Acta anaesthesiologica Scandinavica • 2027-01-15 • Randomized Controlled Trial
N = 98 88/100 PMID 42929478 ↗
Can This Approach Help? Inside the Latest Research on Treatment-Related Changes in Cerebrospinal Fluid Markers of Oxidative Stress and

Analysis of CSF collected prospectively in a large cohort of children treated for ALL demonstrated significant changes in markers of oxidative stress and neurodegeneration within three.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2025-11-03 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 40905823 ↗
New Insights on An Economic Analysis of SC24 in Canada: A Randomized Study of SBRT Compared With: What a 229-Participant Study Found

SBRT is associated with higher upfront costs than CRT.

International journal of radiation oncology, biology, physics • 2024-07-15 • Phase III Randomized Trial
N = 229 82/100 PMID 38218455 ↗
Can This Approach Help? Inside the Latest Research on Automated detection of spinal bone marrow oedema in axial spondyloarthritis:

ML software shows potential for automated MRI BMO assessment in axSpA, offering benefits such as improved consistency, reduced labour costs and minimized inter- and intra-reader variability.

Rheumatology (Oxford, England) • 2025-10-01 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 40489668 ↗
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