Whooping Cough
Also known as: Pertussis
Methodology & AI Transparency ⓘ
Whooping Cough Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: What is whooping cough? Whooping cough, or pertussis, is a respiratory infection that can cause coughing fits.
- 2 Real-world patient consensus: Synonyms for Whooping Cough (A37.90): Pertussis (Lungs & Asthma).
- 3 Typical cash cost range: Clinicians assessing Whooping Cough focus on bronchial smooth-muscle hyperresponsiveness [Whooping Cough A37.90] and targeted history.
- 4 Top reported side effects / signs: Longitudinal Whooping Cough monitoring tracks Spirometry FEV1 / in Whooping Cough (A37.90: FVC Ratio) toward >= 0.75 (FEV1 >= 80% predicted) (A37.90).
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What Is Whooping Cough?
What is whooping cough? Whooping cough, or pertussis, is a respiratory infection that can cause coughing fits. In serious cases, the coughing can become violent and rapid. You may cough so hard that you vomit . The name of the disease comes from the whooping noise you might make when you try to breathe in after coughing. Whooping cough is very contagious and can affect anyone. But it can be especially serious in babies who did not yet get the vaccine. About half of babies under age one who get whooping cough need care in the hospital. What causes whooping cough? Whooping cough is caused by a type of bacteria called Bordetella pertussis. It spreads from person to person.
Pathophysiology, Underlying Causes & Clinical Presentation
In Whooping Cough (A37.90), physiological disruption stems from bronchial smooth-muscle hyperresponsiveness [Whooping Cough A37.90], Cross-referenced with NIH MeSH (Whooping Cough), informing Asthma, COPD & Respiratory Disease protocols that track Fractional Exhaled Nitric in Whooping Cough (A37.90: Oxide (FeNO)) (< 25 ppb (A37.90)).
Common Symptoms & Clinical Signs
- • Mild, occasional cough
- • Fits of many, rapid coughs followed by a high-pitched "whoop" sound
- • Presentation of Whooping Cough (A37.90): episodic wheezing, expiratory in Whooping Cough (A37.90: chest tightness, or)
- • Secondary Whooping Cough clinical sign: chronic productive or in Whooping Cough (A37.90: dry cough worsening)
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
Whooping Cough Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | A37.90 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | Asthma, COPD & Respiratory Disease | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: Spirometry FEV1 / in Whooping Cough (A37.90: FVC Ratio) | >= 0.75 (FEV1 >= 80% predicted) (A37.90) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Fractional Exhaled Nitric in Whooping Cough (A37.90: Oxide (FeNO)) | < 25 ppb (A37.90) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Resting Pulse Oximetry in Whooping Cough (A37.90: (SpO2)) | 96% – 100% (A37.90) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for Whooping Cough
Treatment selection for Whooping Cough depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Whooping Cough)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| New Insights on Segmentectomy Versus Lobectomy in NSCLC With Pathologically Invasive Features: A: What a 1,106-Participant Study Found Segmentectomy demonstrated better OS compared with lobectomy even for NSCLC harboring pathologically invasive features. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer • 2026-10-15 • Phase III Randomized Trial | N = 1,106 | 90/100 | PMID 42119729 ↗ |
| Can This Approach Help? Inside the Latest Research on Interpreting Within-Patient Changes on the EORTC QLQ-C30 and EORTC This study confirms the appropriateness of the 10-point EORTC score threshold generally used by the field for interpreting within-patient changes, but the thresholds proposed from this study enhance interpretability by... The patient • 2022-11-15 • Phase III Randomized Trial | Multi-cohort | 82/100 | PMID 35771392 ↗ |
| Can This Approach Help? Inside the Latest Research on Immunogenicity and safety of adsorbed diphtheria-purified A single-agent Gobik, the first DPT-IPV-Hib pentavalent vaccine approved in Japan, was confirmed to simultaneously provide primary and booster immunizations against Hib infection, pertussis, diphtheria, tetanus, and... Vaccine • 2024-04-30 • Phase III Randomized Trial | Multi-cohort | 82/100 | PMID 38582691 ↗ |
| Can This Approach Help? Inside the Latest Research on Immunogenicity and safety of primary three-dose series with diphtheria, tetanus These data support the potential optimization of China's immunization strategy by transitioning from co-purified to component-based acellular pertussis vaccines to address waning immunity and the ongoing pertussis resurgence. Frontiers in immunology • 2026-01-15 • Phase III Randomized Trial | Multi-cohort | 82/100 | PMID 42483174 ↗ |
Whooping Cough Patient Community & “People Like Me” Threads
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