Switched to Cost Plus Drugs at 25 mg PO with first bite of meal TID for Acarbose; monthly out-of-pocket dropped to $10.38 compared with $64.00 retail.
Acarbose
Brand Reference: Precose
Acarbose Clinical & Real-World Cost Fact Matrix
| Metric | Verified Benchmark | Source |
|---|---|---|
| Acarbose RxNorm Concept ID | 16681 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.1840 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $64.00 / mo | CMS NADAC + U.S. Retail Markup Index |
| Mark Cuban Cost Plus Wholesale Price | $11.80 / mo | Cost Plus Drugs Wholesale Feed |
| Community Mean Out-of-Pocket Paid | $14.50 / mo | 21 Zero-PHI Verified Patient Logs |
Verified Online Prescribers & Wholesale Pharmacies for Acarbose
Acarbose Clinical Pharmacology & DailyMed Monograph
RxCUI 16681 • NDC 00093-7356-01Pseudotetrasaccharide that competitively inhibits small-intestinal brush-border alpha-glucosidases (glucoamylase, sucrase, maltase), blunting postprandial glycemic and insulinemic excursions while increasing colonic short-chain fatty acid fermentation.
Across 21 community cost disclosures for Acarbose (Precose), cash buyers routing around $64.00 retail markups capture a 82% discount ($11.80/mo benchmark vs $0.1840 NADAC acquisition).
Following administration (25 mg PO with first bite of meal TID), Acarbose achieves < 2% absorbed intact from GI lumen bioavailability and immediate intraluminal action with first bite of meal onset, governed by a ~2 hours systemic terminal half-life through degraded exclusively by intestinal bacterial amylases and digestive enzymes.
Before initiating Acarbose at 25 mg PO with first bite of meal TID, clinical safety checklists rule out inflammatory bowel disease or colonic ulceration; cirrhosis; partial intestinal obstruction. Logged tolerability patterns center on flatulence (46% of reports), abdominal borborygmi (28% of reports), soft stools (14% of reports).
Standard Adult Titration & Dosages
Absolute & Relative Contraindications
- Inflammatory bowel disease or colonic ulceration
- Cirrhosis
- Partial intestinal obstruction
Logged Side-Effect Incidence (21 Reports)
Acarbose Patient Dosage Logs & Out-of-Pocket Cost Ledger
Across 21 verified cash-pay logs, Acarbose achieves a 83.40% Worth-It rating with out-of-pocket spend averaging $14.50/mo versus $64.00/mo walk-in retail.
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Completed 10 weeks on Acarbose (50 mg PO TID). Zero notable side effects on steady dosing.
Consistent biomarker response on 100 mg PO TID Acarbose sourced via Cash Clinic ($13.69/mo cash pay without insurance prior authorization).