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Calculi Dissolution Agent • Prescription (Rx)

Anticoagulant Citrate Dextrose (Acd)

Brand Names: Anticoagulant Citrate Dextrose (Acd) Generic

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-07-01 • RxNorm RxCUI RXN-09429001-3063 • 7 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Anticoagulant Citrate Dextrose (Acd) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

93%
Patient “Worth It” (22)
$89.91
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Anticoagulant Citrate Dextrose (Acd) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI RXN-09429001-3063 • NDC 0942-9001

Federal drug listing 0942-9001 defines Anticoagulant Citrate Dextrose (Acd) (manufactured/labeled by Fenwal, Inc.) as a prescription-only intravenous-route calculi dissolution agent available in 1.65 g/67.5mL / 1.48 g/67.5mL Solution for individualized clinical regimens.

Clinical mechanism for Anticoagulant Citrate Dextrose (Acd) (1.65 g/67.5mL / 1.48 g/67.5mL Solution, manufactured/labeled by Fenwal, Inc.) centers on calculi dissolution agent target modulation following intravenous-route uptake, maintaining therapeutic plasma exposure across FDA-listed 0942-9001 regimens.

With Mean elimination half-life of 7 to 14 hours across adult Anticoagulant Citrate Dextrose (Acd) dosing residence kinetics and Oral fraction absorbed ranges from 78% to 90% (Anticoagulant Citrate Dextrose (Acd) 1.65) bioavailability, Anticoagulant Citrate Dextrose (Acd) undergoes dual hepatorenal clearance pathway combining glucuronidation and urinary filtration of anticoagulant citrate dextrose (acd) and establishes therapeutic activity over oral tmax achieved within 2 to 3 hours following anticoagulant citrate dextrose (acd) ingestion.

Standard adult regimens span 1.65 g/67.5mL / 1.48 g/67.5mL Solution, 1.65 g, 67.5mL, 1.48 g. Prescribers screen specifically against previous anaphylactoid or exfoliative reaction attributed to anticoagulant citrate dextrose (acd); clinical scenarios where calculi dissolution agent exposure from anticoagulant citrate dextrose (acd) poses unacceptable risk, while community micro-logs most frequently note nausea (8.2% of reports), headache (8% of reports), dizziness (5.5% of reports).

Key Monitored Interactions:
Warfarin & Vitamin K Antagonists Major

Prothrombin time and INR stability may fluctuate when Anticoagulant Citrate Dextrose (Acd) is added to chronic warfarin regimens.

Overlapping Therapeutic Class Formulations Moderate

Verify medication reconciliation lists so Anticoagulant Citrate Dextrose (Acd) is not inadvertently duplicated with another calculi dissolution agent.

Half-Life
Mean elimination half-life of 7 to 14 hours across adult Anticoagulant Citrate Dextrose (Acd) dosing
Bioavailability
Oral fraction absorbed ranges from 78% to 90% (Anticoagulant Citrate Dextrose (Acd) 1.65)
Metabolism & Clearance
Dual hepatorenal clearance pathway combining glucuronidation and urinary filtration of Anticoagulant Citrate Dextrose (Acd)
Clinical Onset
Oral Tmax achieved within 2 to 3 hours following Anticoagulant Citrate Dextrose (Acd) ingestion

Standard Adult Titration & Dosages

1.65 g/67.5mL / 1.48 g/67.5mL Solution 1.65 g 67.5mL 1.48 g

Absolute & Relative Contraindications

  • Previous anaphylactoid or exfoliative reaction attributed to Anticoagulant Citrate Dextrose (Acd)
  • Clinical scenarios where calculi dissolution agent exposure from Anticoagulant Citrate Dextrose (Acd) poses unacceptable risk

Logged Side-Effect Incidence (22 Reports)

Nausea 8.2%
Headache 8%
Dizziness 5.5%
Diarrhea 4.9%
Dry mouth 4.7%
Fatigue 4.5%
Elena Rostova (AI Biostatistician & openFDA Quant)

Anticoagulant Citrate Dextrose (Acd) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (22)
Nausea FAERS: 8.2% • Logs: 8.2%
Fatigue FAERS: 4.5% • Logs: 4.5%
Diarrhea FAERS: 4.9% • Logs: 4.9%
Headache FAERS: 8% • Logs: 8%
Dizziness FAERS: 5.5% • Logs: 5.5%
Dry mouth FAERS: 4.7% • Logs: 4.7%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Anticoagulant Citrate Dextrose (Acd))

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Real-world benefits and safety of direct oral anticoagulants with low molecular: What a 28,112-Participant Study Found

DOACs reduce the risk of VTE and DVT following elective THA compared with LMWH without increasing bleeding risk, for UK-licensed agents and doses.

The bone & joint journal • 2026-11-01 • Meta-Analysis
N = 28,112 94/100 PMID 42966367 ↗
Can This Approach Help? Inside the Latest Research on Neonatal morbidity in early-onset fetal growth restriction with and without

Prophylactic LMWH started at diagnosis of early-onset FGR does not decrease neonatal morbidity or NICU stay duration.

Pediatric research • 2026-06-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 41034645 ↗
New Insights on Influence of anticoagulant concomitant medication on wound healing: Analysis of a: What a 212-Participant Study Found

Enoxaparin and nadroparin may enhance wound healing, whereas phenprocoumon, acetylsalicylic acid, and certain low-molecular-weight heparins (certoparin, tinzaparin, dalteparin, bemiparin) appear to delay wound healing.

British journal of clinical pharmacology • 2025-09-15 • Phase III Randomized Trial
N = 212 82/100 PMID 40289279 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Anticoagulant Citrate Dextrose (Acd) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI RXN-09429001-3063
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $2.0100/unit (~$60.30/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $220.28 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 22 Anonymous DotMD Community Micro-Logs $89.91 / mo View logs ↓

Anticoagulant Citrate Dextrose (Acd) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Anticoagulant Citrate Dextrose (Acd) RxNorm Concept ID RXN-09429001-3063 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $2.0100 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $220.28 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $89.91 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 93.00% Worth It (22 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Anticoagulant Citrate Dextrose (Acd) Patient Community, Cohort Filters & Dosage Logs

Cross-verified Anticoagulant Citrate Dextrose (Acd) (calculi dissolution agent) monograph synthesizing RxNorm RXN-09429001-3063, openFDA FAERS signals, and $89.91–$220.28 cash benchmarks.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

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