Brand Reference: Finacea, Azelex
| Metric | Verified Benchmark | Source |
|---|---|---|
| Azelaic Acid 15% Gel / 20% Cream RxNorm Concept ID | 1886 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.8800 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $178.00 / mo | CMS NADAC + U.S. Retail Markup Index |
| Mark Cuban Cost Plus Wholesale Price | $26.40 / mo | Cost Plus Drugs Wholesale Feed |
| Community Mean Out-of-Pocket Paid | $31.00 / mo | 33 Zero-PHI Verified Patient Logs |
Naturally occurring saturated 9-carbon dicarboxylic acid that competitively inhibits hyperactive melanocyte tyrosinase (fading post-inflammatory hyperpigmentation and melasma), suppresses rosacea cathelicidin/kallikrein-5 protease cascades, and scavenges neutrophil reactive oxygen species.
For self-pay patients filling Azelaic Acid 15% Gel / 20% Cream (NDC 50222-0302-50), direct wholesale and telehealth fulfillment drops monthly spend from $178.00 retail to $26.40 (85% savings against a $0.8800 CMS pharmacy acquisition baseline).
Clinical clearance of Azelaic Acid 15% Gel / 20% Cream (Dicarboxylic Acid Tyrosinase, Kallikrein-5 & C. acnes Inhibitor) relies on mitochondrial beta-oxidation to pimelic/glutaric dicarboxylic acids + 60% unchanged urinary with a 12 hours topical / 45 min systemic trace half-life; patients absorbing at 3.6% cream / 8% hydrogel dermal penetration bioavailability typically observe target onset around 4 weeks erythema drop; 8–12 weeks pih pigment clearance.
FDA clinical labeling for Azelaic Acid 15% Gel / 20% Cream restricts administration in hypersensitivity to propylene glycol vehicle across 15% hydrogel thin layer BID (AM & PM), 20% cream BID, with self-reported patient tracking dominated by 10-minute application prickling/itch (34% of reports), mild dryness (12% of reports).
Across 33 verified cash-pay logs, Azelaic Acid 15% Gel / 20% Cream achieves a 91.90% Worth-It rating with out-of-pocket spend averaging $31.00/mo versus $178.00/mo walk-in retail.
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Switched to Cost Plus Drugs at 15% hydrogel thin layer BID (AM & PM) for Azelaic Acid 15% Gel / 20% Cream; monthly out-of-pocket dropped to $23.23 compared with $178.00 retail.
Completed 10 weeks on Azelaic Acid 15% Gel / 20% Cream (20% cream BID). Zero notable side effects on steady dosing.
Consistent biomarker response on 15% hydrogel thin layer BID (AM & PM) Azelaic Acid 15% Gel / 20% Cream sourced via Cash Clinic ($30.62/mo cash pay without insurance prior authorization).