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Pediculicide • Over-the-Counter (OTC)

Benzyl Alcohol/Pramoxine Hydrochloride

Brand Names: Itch X

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2024-12-05 • RxNorm RxCUI 1293632 • 9 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Benzyl Alcohol/Pramoxine Hydrochloride Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

76%
Patient “Worth It” (18)
$49.00
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Benzyl Alcohol/Pramoxine Hydrochloride

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Dr. Vance (AI Pharmacology & Interaction Agent)

Benzyl Alcohol/Pramoxine Hydrochloride Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 1293632 • NDC 0225-0495

Use Temporarily relieves pain and itching associated with insect bites, minor burns, sunburn, minor cuts, scrapes, minor skin irritations, hives and rashes due to poison ivy, poison oak, or poison sumac

In clinical regimens (10 g/100g / 1 g/100g Gel, Longitudinal Benzyl Alcohol/Pramoxine Hydrochloride dosing interval tailored to tolerability), Benzyl Alcohol/Pramoxine Hydrochloride executes pediculicide target modulation documented under federal RxCUI 1293632 and DailyMed 2024-12-05 labeling.

With Depot mucosal/cutaneous persistence without significant systemic accumulation of Benzyl Alcohol/Pramoxine Hydrochloride residence kinetics and < 5% transdermal or mucosal systemic uptake from Benzyl Alcohol/Pramoxine Hydrochloride bioavailability, Benzyl Alcohol/Pramoxine Hydrochloride undergoes local esterase/enzymatic cleavage of benzyl alcohol/pramoxine hydrochloride with minimal hepatic cytochrome burden and establishes therapeutic activity over initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (benzyl alcohol/pramoxine hydrochloride).

Standard adult regimens span 10 g/100g / 1 g/100g Gel, Longitudinal Benzyl Alcohol/Pramoxine Hydrochloride dosing interval tailored to tolerability. Prescribers screen specifically against severe drug-induced hypersensitivity to benzyl alcohol/pramoxine hydrochloride or inactive tablet/vehicle binders; prohibited co-prescriptions or physiological states specified in fda spl 2024-12-05 for benzyl alcohol/pramoxine hydrochloride, while community micro-logs most frequently note nausea (8.2% of reports), headache (8% of reports), fatigue (5.6% of reports).

Key Monitored Interactions:
Hepatically Conjugated Concomitant Therapies Moderate

Assess baseline hepatic panels and interacting prescriptions when starting Benzyl Alcohol/Pramoxine Hydrochloride (pediculicide).

Herbal CYP/Transporter Supplements (St. John’s Wort, Grapefruit) Minor

Botanical enzyme modulators may alter oral first-pass exposure of Benzyl Alcohol/Pramoxine Hydrochloride; disclose all supplements.

Half-Life
Depot mucosal/cutaneous persistence without significant systemic accumulation of Benzyl Alcohol/Pramoxine Hydrochloride
Bioavailability
< 5% transdermal or mucosal systemic uptake from Benzyl Alcohol/Pramoxine Hydrochloride
Metabolism & Clearance
Local esterase/enzymatic cleavage of Benzyl Alcohol/Pramoxine Hydrochloride with minimal hepatic cytochrome burden
Clinical Onset
Initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (Benzyl Alcohol/Pramoxine Hydrochloride)

Standard Adult Titration & Dosages

10 g/100g / 1 g/100g Gel Longitudinal Benzyl Alcohol/Pramoxine Hydrochloride dosing interval tailored to tolerability

Absolute & Relative Contraindications

  • Severe drug-induced hypersensitivity to Benzyl Alcohol/Pramoxine Hydrochloride or inactive tablet/vehicle binders
  • Prohibited co-prescriptions or physiological states specified in FDA SPL 2024-12-05 for Benzyl Alcohol/Pramoxine Hydrochloride

Logged Side-Effect Incidence (18 Reports)

Nausea 8.2%
Headache 8%
Fatigue 5.6%
Diarrhea 5.5%
Dizziness 5.5%
Pruritus 2.6%
Elena Rostova (AI Biostatistician & openFDA Quant)

Benzyl Alcohol/Pramoxine Hydrochloride Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (18)
Nausea FAERS: 8.2% • Logs: 8.2%
Fatigue FAERS: 5.6% • Logs: 5.6%
Diarrhea FAERS: 5.5% • Logs: 5.5%
Headache FAERS: 8% • Logs: 8%
Pruritus FAERS: 2.6% • Logs: 2.6%
Dizziness FAERS: 5.5% • Logs: 5.5%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Benzyl Alcohol/Pramoxine Hydrochloride)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Benefits and safety of Once-Daily Vilanterol/Fluticasone furoate MDI in: What a 330-Participant Study Found

Once daily VI/FF pMDI was non-inferior to twice daily FOR/FP pMDI in patients with persistent asthma.

The Journal of asthma : official journal of the Association for the Care of Asthma • 2024-10-15 • Phase III Randomized Trial
N = 330 93/100 PMID 38488853 ↗
New Insights on Characterization of Moderate and Severe Asthma Exacerbations in the CAPTAIN: What a 2,436-Participant Study Found

Whereas severe events were associated with greater impact on symptoms, physical activity limitations, and SABA use, onset and time to resolution were generally similar for moderate and severe events.

The journal of allergy and clinical immunology. In practice • 2024-09-15 • Phase III Randomized Trial
N = 2,436 90/100 PMID 38777124 ↗
Can This Approach Help? Inside the Latest Research on Once-daily fluticasone furoate/vilanterol vs once-daily fluticasone furoate in

FF/VI significantly improved weighted mean FEV 1 (0-4 hours; participants aged 5-17 years), but not ΔAM PEF (participants aged 5-11 years) vs FF.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology • 2024-11-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 38936466 ↗
Can This Approach Help? Inside the Latest Research on Effect of Lemborexant on Daytime Functioning in Adults With trouble sleeping:

Prim Care Companion CNS Disord 2025;27(1):24m03810 .

The primary care companion for CNS disorders • 2025-01-16 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 39823487 ↗
Clinic vs. Home Spirometry: Which Works Better for Monitoring Lung Function in Patients With Asthma?

This post hoc comparison of home and clinic spirometry is the largest conducted in asthma.

Chest • 2023-11-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 37385337 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Benzyl Alcohol/Pramoxine Hydrochloride Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 1293632
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $1.0000/unit (~$30.00/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $120.05 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 18 Anonymous DotMD Community Micro-Logs $49.00 / mo View logs ↓

Benzyl Alcohol/Pramoxine Hydrochloride Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Benzyl Alcohol/Pramoxine Hydrochloride RxNorm Concept ID 1293632 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $1.0000 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $120.05 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $49.00 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 76.00% Worth It (18 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Benzyl Alcohol/Pramoxine Hydrochloride Patient Community, Cohort Filters & Dosage Logs

Federal clinical ledger for Benzyl Alcohol/Pramoxine Hydrochloride integrating DailyMed SPL (2024-12-05), CMS NADAC ($1.0000/unit), and 18 Zero-PHI patient logs.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

“People Like Me” Cohort Filter (Zero-PHI)

Filter Benzyl Alcohol/Pramoxine Hydrochloride community threads and patient logs by age, biological sex, dosage, and treatment duration.

No threads match this cohort filter yet. Click + Start Anonymous Discussion to ask the community about Benzyl Alcohol/Pramoxine Hydrochloride.

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