Brand Reference: Winlevi
| Metric | Verified Benchmark | Source |
|---|---|---|
| Clascoterone 1% Cream (Cortexolone 17-Alpha-Propionate) RxNorm Concept ID | 2395793 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $8.9500 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $568.00 / mo | CMS NADAC + U.S. Retail Markup Index |
| Mark Cuban Cost Plus Wholesale Price | $89.00 / mo (Direct TeleMed) | Direct Telehealth Formulary |
| Community Mean Out-of-Pocket Paid | $95.00 / mo | 15 Zero-PHI Verified Patient Logs |
Competes directly with dihydrotestosterone at sebocyte cytoplasmic androgen receptors in both male and female facial skin, suppressing androgen-driven sebum lipid droplet synthesis and IL-6 transcription while hydrolyzing rapidly to inactive cortexolone before reaching systemic circulation.
Out-of-pocket price dispersion on Clascoterone 1% Cream (Cortexolone 17-Alpha-Propionate) spans $95.00 to $568.00 per 30-day fill: pharmacy acquisition benchmarks sit near $8.9500/unit, allowing cash buyers bypassing PBM spread pricing to retain $473.00 each month (83% reduction).
With Rapid dermal esterase cleavage residence kinetics and < 4.5 ng/mL steady-state plasma (safe for male facial use without systemic antiandrogenicity) bioavailability, Clascoterone 1% Cream (Cortexolone 17-Alpha-Propionate) undergoes cutaneous plasma esterase hydrolysis to inactive cortexolone and establishes therapeutic activity over 4–12 weeks sebum and lesion reduction.
Standard adult regimens span 1% cream (~1 gram) applied twice daily (AM & PM). Prescribers screen specifically against hypothalamic-pituitary-adrenal suppression if applied over huge occluded body surface areas in children, while community micro-logs most frequently note localized scaling (12% of reports), erythema (9% of reports).
Across 15 verified cash-pay logs, Clascoterone 1% Cream (Cortexolone 17-Alpha-Propionate) achieves a 83.20% Worth-It rating with out-of-pocket spend averaging $95.00/mo versus $568.00/mo walk-in retail.
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Switched to TeleMed at 1% cream (~1 gram) applied twice daily (AM & PM) for Clascoterone 1% Cream (Cortexolone 17-Alpha-Propionate); monthly out-of-pocket dropped to $83.60 compared with $568.00 retail.
Completed 10 weeks on Clascoterone 1% Cream (Cortexolone 17-Alpha-Propionate) (1% cream (~1 gram) applied twice daily (AM & PM)). Zero notable side effects on steady dosing.
Consistent biomarker response on 1% cream (~1 gram) applied twice daily (AM & PM) Clascoterone 1% Cream (Cortexolone 17-Alpha-Propionate) sourced via Cash Clinic ($110.20/mo cash pay without insurance prior authorization).