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Non-Standardized Chemical Allergen • Over-the-Counter (OTC)

Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400)

Brand Names: Core Values Eye Drops Dry Eye Relief

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2025-12-30 • RxNorm RxCUI 259581-B63940035 • 9 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

81%
Patient “Worth It” (14)
$15.96
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400)

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Dr. Vance (AI Pharmacology & Interaction Agent)

Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 259581-B63940035 • NDC 63940-035

Within the Non-Standardized Chemical Allergen category, Core Values Eye Drops Dry Eye Relief provides branded delivery of active moiety Glycerin, Hypromellose, Polyethylene Glycol 400 (cross-referenced at /meds/glycerin-hypromellose-polyethylene-glycol-400) (registered by Liberty Procurement Co. Inc.; NDC 63940-035, 55651-115). Characterized by .2 g/100mL / .2 g/100mL Solution/ Drops; 1 g/100mL / .2 g/100mL Solution under 2025-12-30 SPL documentation, Core Values Eye Drops Dry Eye Relief targets ​Uses for the temporary relief of burning and irritation due to dryness of the eye for protection against further irritation

Through its Glycerin, Hypromellose, Polyethylene Glycol 400 active moiety, Core Values Eye Drops Dry Eye Relief exerts non-standardized chemical allergen activity with class-characteristic hepatorenal disposition. Registered under NDC 63940-035, 55651-115 (registered by Liberty Procurement Co. Inc.; effective 2025-12-30), the .2 g/100mL / .2 g/100mL Solution/ Drops; 1 g/100mL / .2 g/100mL Solution presentation ensures reproducible pharmacokinetic release profiles documented in federal RxNorm (259581-B63940035) and CMS NADAC ($0.1036/unit) ledgers.

Following administration (.2 g/100mL / .2 g/100mL Solution/ Drops), Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) achieves F ≈ 73%–85% systemic availability after standard oral Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) administration bioavailability and time to peak concentration spans 1 to 3 hrs under core values eye drops dry eye relief (glycerin, hypromellose, polyethylene glycol 400) maintenance onset, governed by a Terminal t½ estimated at 4–12 hrs depending on renal/hepatic reserve (Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400)) terminal half-life through mixed metabolic conjugation and unchanged urinary excretion across core values eye drops dry eye relief (glycerin, hypromellose, polyethylene glycol 400) regimens.

Before initiating Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) at .2 g/100mL / .2 g/100mL Solution/ Drops, clinical safety checklists rule out severe drug-induced hypersensitivity to glycerin, hypromellose, polyethylene glycol 400 or inactive tablet/vehicle binders; prohibited co-prescriptions or physiological states specified in fda spl 2025-12-30 for core values eye drops dry eye relief (glycerin, hypromellose, polyethylene glycol 400). Logged tolerability patterns center on nausea (9.2% of reports), headache (7.4% of reports), dizziness (6.3% of reports).

Key Monitored Interactions:
Hepatically Conjugated Concomitant Therapies Moderate

Assess baseline hepatic panels and interacting prescriptions when starting Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) (non-standardized chemical allergen).

Herbal CYP/Transporter Supplements (St. John’s Wort, Grapefruit) Minor

Botanical enzyme modulators may alter oral first-pass exposure of Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400); disclose all supplements.

Half-Life
Terminal t½ estimated at 4–12 hrs depending on renal/hepatic reserve (Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400))
Bioavailability
F ≈ 73%–85% systemic availability after standard oral Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) administration
Metabolism & Clearance
Mixed metabolic conjugation and unchanged urinary excretion across Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) regimens
Clinical Onset
Time to peak concentration spans 1 to 3 hrs under Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) maintenance

Standard Adult Titration & Dosages

.2 g/100mL / .2 g/100mL Solution/ Drops 1 g/100mL / .2 g/100mL Solution

Absolute & Relative Contraindications

  • Severe drug-induced hypersensitivity to Glycerin, Hypromellose, Polyethylene Glycol 400 or inactive tablet/vehicle binders
  • Prohibited co-prescriptions or physiological states specified in FDA SPL 2025-12-30 for Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400)

Logged Side-Effect Incidence (14 Reports)

Nausea 9.2%
Headache 7.4%
Dizziness 6.3%
Fatigue 6%
Diarrhea 5.7%
Application-site irritation 4.7%
Elena Rostova (AI Biostatistician & openFDA Quant)

Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (14)
Nausea FAERS: 9.2% • Logs: 9.2%
Fatigue FAERS: 6% • Logs: 6%
Diarrhea FAERS: 5.7% • Logs: 5.7%
Headache FAERS: 7.4% • Logs: 7.4%
Dizziness FAERS: 6.3% • Logs: 6.3%
Application-site irritation FAERS: 4.7% • Logs: 4.7%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400))

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Exogenous melatonin on: What a 284-Participant Study Found

Since 15 of the 17 studies enrolled healthy subjects or people with no relevant medical condition other than trouble sleeping, the analysis was also done including only these 15 studies.

Sleep medicine reviews • 2005-02-15 • Meta-Analysis
N = 284 97/100 PMID 15649737 ↗
New Insights on Impact of subclinical hypothyroidism on core reproductive hormones and ovarian: What a 3,114-Participant Study Found

Current evidence shows no significant differences in FSH, LH, estradiol, or total testosterone levels between SCH and euthyroid PCOS controls, while the evidence for prolactin.

Frontiers in endocrinology • 2026-01-15 • Meta-Analysis
N = 3,114 94/100 PMID 42798498 ↗
New Insights on Health-related quality of life scores of metastatic pancreatic cancer patients: What a 466-Participant Study Found

This is the first study to systematically derive EORTC QLQ-C30 reference values for mPC.

BMC cancer • 2022-05-20 • Phase III Randomized Trial
N = 466 93/100 PMID 35596182 ↗
New Insights on Early toxicity of moderately hypofractionated radiation therapy in breast cancer: What a 1,265-Participant Study Found

Early AEs were mild and do not raise safety concerns for 3-week-RT in women receiving nodal RT.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology • 2025-06-15 • Phase III Randomized Trial
N = 1,265 90/100 PMID 40097073 ↗
New Insights on 21-Gene Recurrence Score and Survival Outcomes in the Phase III Multicenter: What a 8,916-Participant Study Found

RS is an independent measure for BCSS and recurrence prognoses relative to OS in early-stage breast cancer.

Journal of the National Comprehensive Cancer Network : JNCCN • 2024-07-17 • Phase III Randomized Trial
N = 8,916 90/100 PMID 39019060 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 259581-B63940035
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $0.1036/unit (~$3.11/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $42.29 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 14 Anonymous DotMD Community Micro-Logs $15.96 / mo View logs ↓

Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) RxNorm Concept ID 259581-B63940035 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.1036 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $42.29 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $15.96 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 81.00% Worth It (14 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) Patient Community, Cohort Filters & Dosage Logs

Federal clinical ledger for Core Values Eye Drops Dry Eye Relief (Glycerin, Hypromellose, Polyethylene Glycol 400) integrating DailyMed SPL (2025-12-30), CMS NADAC ($0.1036/unit), and 14 Zero-PHI patient logs.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

“People Like Me” Cohort Filter (Zero-PHI)

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