Dilantin-125 (Phenytoin)
Brand Names: Dilantin-125
Methodology & AI Transparency ⓘ
Dilantin-125 (Phenytoin) Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: FDA DailyMed monograph 2025-05-28 designates Dilantin-125 (NDC 58151-115, registered by Viatris Specialty LLC) as a prescription brand-name anti-epileptic agent formulation of Phenytoin.
- 2 Real-world patient consensus: Commercial Dilantin-125 monograph (125 mg/5mL Suspension) cross-indexed with generic Phenytoin for therapeutic equivalence review.
- 3 Typical cash cost range: Public pharmacy ledger: $14.23 low cash benchmark vs. $37.71 chain retail average ($0.0796/unit CMS NADAC).
- 4 Top reported side effects / signs: Most commonly reported Dilantin-125 (Phenytoin) tolerability events: nausea (7.6%), headache (7.7%), dizziness (6.5%).
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Dilantin-125 (Phenytoin) Mechanism, CYP450 Pathways & DailyMed Monograph
FDA DailyMed monograph 2025-05-28 designates Dilantin-125 (NDC 58151-115, registered by Viatris Specialty LLC) as a prescription brand-name anti-epileptic agent formulation of Phenytoin. Supplied across 125 mg/5mL Suspension; 50mg Tablet Chewable, Dilantin-125 is utilized in Phenytoin oral suspension is indicated for the treatment of tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures.
Clinical pharmacology for Dilantin-125 is driven by Phenytoin acting within anti-epileptic agent signaling cascades involving CYP2C9/CYP2C19 clearance pathways. Distributed across 125 mg/5mL Suspension; 50mg Tablet Chewable (NDC 58151-115; registered by Viatris Specialty LLC), the branded formulation calibrates systemic exposure and patient adherence, with public 30-day cash benchmarks ranging from $14.23 to $37.71.
Following administration (125 mg/5mL Suspension), Dilantin-125 (Phenytoin) achieves Consistent 52%–64% gastrointestinal absorption profile for Dilantin-125 (Phenytoin) bioavailability and cmax attained 2–3 hours post-administration of dilantin-125 (phenytoin) onset, governed by a Elimination kinetics span 5 to 15 hours per Dilantin-125 (Phenytoin) clinical pharmacology terminal half-life through cytochrome cyp2c9, cyp2c19 biotransformation with dual hepatorenal elimination.
Before initiating Dilantin-125 (Phenytoin) at 125 mg/5mL Suspension, clinical safety checklists rule out history of severe allergic sensitivity to dilantin-125 (phenytoin) active moiety or formulation vehicle; acute clinical instability or interacting polypharmacy excluded under 2025-05-28 phenytoin labeling. Logged tolerability patterns center on headache (7.7% of reports), nausea (7.6% of reports), dizziness (6.5% of reports).
Chronic enzyme induction shortens Dilantin-125 (Phenytoin) persistence in plasma and reduces steady-state exposure.
Systemic bioavailability and half-life of Dilantin-125 (Phenytoin) respond to strong CYP2C9 enzymatic inhibition or induction.
Standard Adult Titration & Dosages
Absolute & Relative Contraindications
- History of severe allergic sensitivity to Dilantin-125 (Phenytoin) active moiety or formulation vehicle
- Acute clinical instability or interacting polypharmacy excluded under 2025-05-28 Phenytoin labeling
Logged Side-Effect Incidence (9 Reports)
Dilantin-125 (Phenytoin) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Dilantin-125 (Phenytoin))
Human clinical trial evidence for Dilantin-125 (Phenytoin) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .
Dilantin-125 (Phenytoin) Public Price Transparency Ledger
| Dispensing Channel / Benchmark | Verification Source | Reference Cost | Details |
|---|---|---|---|
| Pharmacy Acquisition Cost (CMS NADAC) | CMS Medicaid NADAC Weekly National Survey | $0.0796/unit (~$2.39/30u) | Wholesale baseline |
| Average U.S. Walk-In Retail Cash Price | Chain Pharmacy Uninsured Cash Index | $37.71 / mo | Before coupon/insurance |
| Patient-Logged Out-of-Pocket Average | 9 Anonymous DotMD Community Micro-Logs | $14.23 / mo | View logs ↓ |
Dilantin-125 (Phenytoin) Federal Verification & Benchmark Summary
| Metric | Verified Benchmark | Source |
|---|---|---|
| Dilantin-125 (Phenytoin) RxNorm Concept ID | 1313885-B58151115 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.0796 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $37.71 / mo | U.S. Uninsured Retail Cash Index |
| Public Mail-Order Wholesale Benchmark | $14.23 / mo (Patient Mean) | Public Cash Reference |
| Real-World Patient Consensus | 88.00% Worth It (9 anonymous logs) | DotMD Zero-PHI Patient Ledger |
Dilantin-125 (Phenytoin) Patient Community, Cohort Filters & Dosage Logs
Federal clinical ledger for Dilantin-125 (Phenytoin) integrating DailyMed SPL (2025-05-28), CMS NADAC ($0.0796/unit), and 9 Zero-PHI patient logs.
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Filter Dilantin-125 (Phenytoin) community threads and patient logs by age, biological sex, dosage, and treatment duration.