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Anti-coagulant • Over-the-Counter (OTC)

Earthmed Soothe Chewable Orange (Citric Acid)

Brand Names: Earthmed Soothe Chewable Orange

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2025-11-14 • RxNorm RxCUI RXN-B82876981 • 4 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Earthmed Soothe Chewable Orange (Citric Acid) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

80%
Patient “Worth It” (19)
$113.62
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Earthmed Soothe Chewable Orange (Citric Acid) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI RXN-B82876981 • NDC 82876-981

Earthmed Soothe Chewable Orange is a over-the-counter branded anti-coagulant product delivering active moiety Citric Acid (cross-referenced at /meds/anhydrous-citric-acid), registered by Earthmed LLC under NDC 82876-981, 82876-984. Updated in FDA DailyMed SPL on 2025-11-14, this branded presentation (1.5 g/108.27g Chewable Gel; Stepwise Citric Acid titration guided by clinical response and eGFR) supports Uses For the relief of Heartburn, acid indigestion, and upset stomach associated with these symptoms.

Pharmacologically, Earthmed Soothe Chewable Orange derives its clinical activity from Citric Acid, a anti-coagulant molecule with class-characteristic hepatorenal disposition. Branded finished-dosage manufacturing (1.5 g/108.27g Chewable Gel; Stepwise Citric Acid titration guided by clinical response and eGFR; registered by Earthmed LLC) governs excipient dissolution and release kinetics while maintaining bioequivalence benchmarks relative to reference Citric Acid (CMS NADAC $1.4600/unit vs. $301.09 retail).

Pharmacokinetic profiling of Earthmed Soothe Chewable Orange (Citric Acid) demonstrates an elimination half-life of Localized tissue retention for Earthmed Soothe Chewable Orange (Citric Acid) with minimal systemic plasma half-life with < 5% transdermal or mucosal systemic uptake from Earthmed Soothe Chewable Orange (Citric Acid) systemic bioavailability; clearance proceeds via local esterase/enzymatic cleavage of earthmed soothe chewable orange (citric acid) with minimal hepatic cytochrome burden, reaching clinical onset within initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (earthmed soothe chewable orange (citric acid)).

Titration schedules for Earthmed Soothe Chewable Orange (Citric Acid) (1.5 g/108.27g Chewable Gel → Stepwise Citric Acid titration guided by clinical response and eGFR) require excluding prior anaphylaxis, angioedema, or severe hypersensitivity to citric acid or earthmed soothe chewable orange (citric acid) excipients; co-administration with prohibited interacting drugs or decompensated organ failure per 2025-11-14 earthmed soothe chewable orange (citric acid) spl; real-world patient logs highlight nausea (8.1% of reports), headache (6.9% of reports), dyspepsia (6.4% of reports) alongside a 80.00% Worth-It consensus.

Key Monitored Interactions:
Duplicate Anti-coagulant Agents Moderate

Avoid overlapping anti-coagulant prescriptions alongside Earthmed Soothe Chewable Orange (Citric Acid) to prevent cumulative receptor toxicity.

Gastric pH-Altering Agents (PPIs & H2 Blockers) Minor

Shifts in intragastric pH can modestly influence dissolution kinetics of oral Earthmed Soothe Chewable Orange (Citric Acid) dosage forms.

Half-Life
Localized tissue retention for Earthmed Soothe Chewable Orange (Citric Acid) with minimal systemic plasma half-life
Bioavailability
< 5% transdermal or mucosal systemic uptake from Earthmed Soothe Chewable Orange (Citric Acid)
Metabolism & Clearance
Local esterase/enzymatic cleavage of Earthmed Soothe Chewable Orange (Citric Acid) with minimal hepatic cytochrome burden
Clinical Onset
Initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (Earthmed Soothe Chewable Orange (Citric Acid))

Standard Adult Titration & Dosages

1.5 g/108.27g Chewable Gel Stepwise Citric Acid titration guided by clinical response and eGFR

Absolute & Relative Contraindications

  • Prior anaphylaxis, angioedema, or severe hypersensitivity to Citric Acid or Earthmed Soothe Chewable Orange (Citric Acid) excipients
  • Co-administration with prohibited interacting drugs or decompensated organ failure per 2025-11-14 Earthmed Soothe Chewable Orange (Citric Acid) SPL

Logged Side-Effect Incidence (19 Reports)

Nausea 8.1%
Headache 6.9%
Dyspepsia 6.4%
Dizziness 5%
Fatigue 4.3%
Diarrhea 3.7%
Elena Rostova (AI Biostatistician & openFDA Quant)

Earthmed Soothe Chewable Orange (Citric Acid) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (19)
Nausea FAERS: 8.1% • Logs: 8.1%
Fatigue FAERS: 4.3% • Logs: 4.3%
Diarrhea FAERS: 3.7% • Logs: 3.7%
Headache FAERS: 6.9% • Logs: 6.9%
Dizziness FAERS: 5% • Logs: 5%
Dyspepsia FAERS: 6.4% • Logs: 6.4%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Earthmed Soothe Chewable Orange (Citric Acid))

Browse All PubMed Translations →

Human clinical trial evidence for Earthmed Soothe Chewable Orange (Citric Acid) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .

Marcus Sterling (AI Healthcare Price Auditor)

Earthmed Soothe Chewable Orange (Citric Acid) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI RXN-B82876981
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $1.4600/unit (~$43.80/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $301.09 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 19 Anonymous DotMD Community Micro-Logs $113.62 / mo View logs ↓

Earthmed Soothe Chewable Orange (Citric Acid) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Earthmed Soothe Chewable Orange (Citric Acid) RxNorm Concept ID RXN-B82876981 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $1.4600 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $301.09 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $113.62 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 80.00% Worth It (19 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Earthmed Soothe Chewable Orange (Citric Acid) Patient Community, Cohort Filters & Dosage Logs

Cross-verified Earthmed Soothe Chewable Orange (Citric Acid) (anti-coagulant) monograph synthesizing RxNorm RXN-B82876981, openFDA FAERS signals, and $113.62–$301.09 cash benchmarks.

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“People Like Me” Cohort Filter (Zero-PHI)

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