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Over-the-Counter Clinical Monograph • Over-the-Counter (OTC)

Hand (Lotion)

Brand Names: Hand

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2024-10-09 • RxNorm RxCUI 1809903-B70741006 • 9 Linked .gov / PubMed Citations • Governance: Dr. Priya Nair, MD, FAAD (NPI #1295730425)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Hand (Lotion) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

82%
Patient “Worth It” (14)
$126.58
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Hand (Lotion)

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Dr. Vance (AI Pharmacology & Interaction Agent)

Hand (Lotion) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 1809903-B70741006 • NDC 70741-006

As a proprietary over-the-counter clinical monograph presentation registered by Derma Glove, Hand supplies active pharmaceutical ingredient Lotion in 70 mL/100mL Lotion; 53.5 g/100mL Gel (NDC 70741-006, 71087-001; SPL 2024-10-09). Clinical prescribing and dispensing guidelines focus on Apply lotion directly onto body and rub with hands until dry.

The active constituent inside Hand—Lotion—functions as a targeted over-the-counter clinical monograph agent with class-characteristic hepatorenal disposition. While therapeutic target engagement mirrors generic Lotion, Hand (registered by Derma Glove, SPL 2024-10-09) specifies proprietary packaging (70741-006, 71087-001) and 70 mL/100mL Lotion; 53.5 g/100mL Gel quality controls alongside a $1.6400/unit NADAC acquisition baseline.

Clinical clearance of Hand (Lotion) (Over-the-Counter Clinical Monograph) relies on local esterase/enzymatic cleavage of hand (lotion) with minimal hepatic cytochrome burden with a Depot mucosal/cutaneous persistence without significant systemic accumulation of Hand (Lotion) half-life; patients absorbing at < 5% transdermal or mucosal systemic uptake from Hand (Lotion) bioavailability typically observe target onset around initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (hand (lotion)).

FDA clinical labeling for Hand (Lotion) restricts administration in documented intolerance or hypersensitivity reaction involving lotion (over-the-counter clinical monograph); concurrent restricted medications flagged in section 4/7 of the hand (lotion) dailymed monograph (1809903-b70741006) across 70 mL/100mL Lotion, 53.5 g/100mL Gel, 53.3 g/100mL Liquid, with self-reported patient tracking dominated by nausea (8.4% of reports), headache (8.1% of reports), dizziness (6.7% of reports).

Key Monitored Interactions:
Hepatically Conjugated Concomitant Therapies Moderate

Assess baseline hepatic panels and interacting prescriptions when starting Hand (Lotion) (over-the-counter clinical monograph).

Herbal CYP/Transporter Supplements (St. John’s Wort, Grapefruit) Minor

Botanical enzyme modulators may alter oral first-pass exposure of Hand (Lotion); disclose all supplements.

Half-Life
Depot mucosal/cutaneous persistence without significant systemic accumulation of Hand (Lotion)
Bioavailability
< 5% transdermal or mucosal systemic uptake from Hand (Lotion)
Metabolism & Clearance
Local esterase/enzymatic cleavage of Hand (Lotion) with minimal hepatic cytochrome burden
Clinical Onset
Initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (Hand (Lotion))

Standard Adult Titration & Dosages

70 mL/100mL Lotion 53.5 g/100mL Gel 53.3 g/100mL Liquid

Absolute & Relative Contraindications

  • Documented intolerance or hypersensitivity reaction involving Lotion (over-the-counter clinical monograph)
  • Concurrent restricted medications flagged in Section 4/7 of the Hand (Lotion) DailyMed monograph (1809903-B70741006)

Logged Side-Effect Incidence (14 Reports)

Nausea 8.4%
Headache 8.1%
Dizziness 6.7%
Fatigue 6.2%
Diarrhea 4.7%
Dry mouth 3.5%
Elena Rostova (AI Biostatistician & openFDA Quant)

Hand (Lotion) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (14)
Nausea FAERS: 8.4% • Logs: 8.4%
Fatigue FAERS: 6.2% • Logs: 6.2%
Diarrhea FAERS: 4.7% • Logs: 4.7%
Headache FAERS: 8.1% • Logs: 8.1%
Dizziness FAERS: 6.7% • Logs: 6.7%
Dry mouth FAERS: 3.5% • Logs: 3.5%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Hand (Lotion))

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients: What a 1,614-Participant Study Found

Once-daily treatment with tazarotene 0.045% polymeric emulsion lotion may help improve patient-perceived skin oiliness in those with moderate-to-severe acne.

The Journal of dermatological treatment • 2023-12-15 • Randomized Controlled Trial
N = 1,614 96/100 PMID 36382987 ↗
New Insights on Efficacy and Tolerability of a Novel Tretinoin 0.05% Lotion for the Once-Daily: What a 551-Participant Study Found

Conclusions: Tretinoin 0.05% lotion was significantly more effective than vehicle in achieving treatment success and reducing inflammatory and noninflammatory lesions in adult females with moderate acne, with notable...

Journal of drugs in dermatology : JDD • 2019-11-01 • Randomized Controlled Trial
N = 551 93/100 PMID 31741360 ↗
New Insights on Effect of Delgocitinib Cream on Health-Related Quality of Life in Patients With: What a 639-Participant Study Found

Delgocitinib cream resulted in clinically significant improvement in HRQoL compared with cream vehicle.

Contact dermatitis • 2026-07-15 • Phase III Randomized Trial
N = 639 93/100 PMID 41775339 ↗
New Insights on Tazarotene 0.045% Lotion for Moderate-to-Severe Acne Patients: Pooled Phase 3: What a 1,013-Participant Study Found

Tazarotene 0.045% lotion is efficacious and well tolerated in female and male adolescents and adults with moderate-to-severe acne.

Journal of drugs in dermatology : JDD • 2021-06-01 • Phase III Randomized Trial
N = 1,013 90/100 PMID 34076400 ↗
New Insights on Effects of Once-Daily Tretinoin 0.05% Lotion on Quality of Life in Patients with: What a 1,640-Participant Study Found

Participants with moderate-to-severe acne reported better quality of life after 12 weeks of treatment with tretinoin 0.05% lotion.

American journal of clinical dermatology • 2020-12-15 • Phase III Randomized Trial
N = 1,640 90/100 PMID 32886337 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Hand (Lotion) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 1809903-B70741006
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $1.6400/unit (~$49.20/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $335.44 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 14 Anonymous DotMD Community Micro-Logs $126.58 / mo View logs ↓

Hand (Lotion) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Hand (Lotion) RxNorm Concept ID 1809903-B70741006 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $1.6400 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $335.44 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $126.58 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 82.00% Worth It (14 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Hand (Lotion) Patient Community, Cohort Filters & Dosage Logs

Federal clinical ledger for Hand (Lotion) integrating DailyMed SPL (2024-10-09), CMS NADAC ($1.6400/unit), and 14 Zero-PHI patient logs.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

“People Like Me” Cohort Filter (Zero-PHI)

Filter Hand (Lotion) community threads and patient logs by age, biological sex, dosage, and treatment duration.

No threads match this cohort filter yet. Click + Start Anonymous Discussion to ask the community about Hand (Lotion).

Recent Verified Anonymous Patient Micro-Logs (0)