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Nonsteroidal Anti-inflammatory Drug • Over-the-Counter (OTC)

Ibuprofen 200mg

Brand Names: Physicians Care Ibuprofen

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2025-03-04 • RxNorm RxCUI 310965 • 6 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Ibuprofen 200mg Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

83%
Patient “Worth It” (15)
$9.90
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Ibuprofen 200mg

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Dr. Vance (AI Pharmacology & Interaction Agent)

Ibuprofen 200mg Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 310965 • NDC 69168-382

Uses: temporarily relieves minor aches and pains due to: ■ headache ■ toothache ■ backache ■ menstrual cramps ■ the common cold ■ muscular aches ■ minor pain of arthritis ■ temporarily reduces fever

As an active nonsteroidal anti-inflammatory drug moiety (Redicare LLC), Ibuprofen 200mg modulates physiological signaling proportional to 200 mg/1 Tablet, Coated exposure and hepatorenal clearance (SPL 2025-03-04).

Following administration (200 mg/1 Tablet, Coated), Ibuprofen 200mg achieves Approximately 68% to 80% enteral uptake across labeled Ibuprofen 200mg strengths bioavailability and maximum serum exposure occurs 2–4 hours after ibuprofen 200mg dosing onset, governed by a Steady-state plasma equilibrium reached over 6–16 hour t½ intervals for Ibuprofen 200mg terminal half-life through predominantly hepatic biotransformation with renal elimination of polar ibuprofen 200mg conjugates.

Before initiating Ibuprofen 200mg at 200 mg/1 Tablet, Coated, clinical safety checklists rule out previous anaphylactoid or exfoliative reaction attributed to ibuprofen 200mg; clinical scenarios where nonsteroidal anti-inflammatory drug exposure from ibuprofen 200mg poses unacceptable risk. Logged tolerability patterns center on headache (11.5% of reports), nausea (7.8% of reports), fatigue (5.6% of reports).

Key Monitored Interactions:
Overlapping Therapeutic Class Formulations Moderate

Verify medication reconciliation lists so Ibuprofen 200mg is not inadvertently duplicated with another nonsteroidal anti-inflammatory drug.

Ethanol & Dietary Bioavailability Modifiers Minor

Alcohol or high-fat meal timing can shift absorption rate and orthostatic tolerance during Ibuprofen 200mg dosing.

Half-Life
Steady-state plasma equilibrium reached over 6–16 hour t½ intervals for Ibuprofen 200mg
Bioavailability
Approximately 68% to 80% enteral uptake across labeled Ibuprofen 200mg strengths
Metabolism & Clearance
Predominantly hepatic biotransformation with renal elimination of polar Ibuprofen 200mg conjugates
Clinical Onset
Maximum serum exposure occurs 2–4 hours after Ibuprofen 200mg dosing

Standard Adult Titration & Dosages

200 mg/1 Tablet, Coated 200 mg/1 Tablet 200 mg/1 Tablet, Film Coated

Absolute & Relative Contraindications

  • Previous anaphylactoid or exfoliative reaction attributed to Ibuprofen 200mg
  • Clinical scenarios where nonsteroidal anti-inflammatory drug exposure from Ibuprofen 200mg poses unacceptable risk

Logged Side-Effect Incidence (15 Reports)

Headache 11.5%
Nausea 7.8%
Fatigue 5.6%
Dizziness 5.4%
Diarrhea 4.4%
Dry mouth 3.3%
Elena Rostova (AI Biostatistician & openFDA Quant)

Ibuprofen 200mg Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (15)
Nausea FAERS: 7.8% • Logs: 7.8%
Fatigue FAERS: 5.6% • Logs: 5.6%
Diarrhea FAERS: 4.4% • Logs: 4.4%
Headache FAERS: 11.5% • Logs: 11.5%
Dizziness FAERS: 5.4% • Logs: 5.4%
Dry mouth FAERS: 3.3% • Logs: 3.3%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Ibuprofen 200mg)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Pain relief Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative: What a 345-Participant Study Found

Intermittent IV administration of ibuprofen 400 mg or 800 mg within 24 h after surgery in patients undergoing abdominal and orthopedic surgery significantly decreased morphine consumption and relieved pain, without increasing...

Pain research & management • 2023-01-15 • Phase III Randomized Trial
N = 345 93/100 PMID 36926379 ↗
Can This Approach Help? Inside the Latest Research on Ibuprofen alters human testicular physiology to produce a state of compensated

This effect was also observed in a human steroidogenic cell line.

Proceedings of the National Academy of Sciences of the United States of America • 2018-01-23 • Randomized Controlled Trial
Multi-cohort 82/100 PMID 29311296 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Ibuprofen 200mg Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 310965
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $0.0345/unit (~$1.04/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $34.50 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 15 Anonymous DotMD Community Micro-Logs $9.90 / mo View logs ↓

Ibuprofen 200mg Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Ibuprofen 200mg RxNorm Concept ID 310965 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.0345 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $34.50 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $9.90 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 83.00% Worth It (15 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Ibuprofen 200mg Patient Community, Cohort Filters & Dosage Logs

Evidence synthesis for Ibuprofen 200mg: FDA labeling (2025-03-04, NDC 69168-382), CYP/interaction screening, and public pharmacy acquisition costs.

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“People Like Me” Cohort Filter (Zero-PHI)

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