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Histamine-2 Receptor Antagonist • Over-the-Counter (OTC)

Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide)

Brand Names: Injoy Heartburn Relief

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2022-09-07 • RxNorm RxCUI 283641 • 7 Linked .gov / PubMed Citations • Governance: Dr. Marcus Thorne, MD, FACC (NPI #1184629314)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

86%
Patient “Worth It” (6)
$15.64
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide)

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Dr. Vance (AI Pharmacology & Interaction Agent)

Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 283641 • NDC 0113-6023

Formulated with active pharmaceutical ingredient Famotidine, Calcium Carbonate and Magnesium Hydroxide and registered by L. Perrigo Company, Injoy Heartburn Relief operates as a over-the-counter branded histamine-2 receptor antagonist therapy (RxNorm 283641; NDC 0113-6023, 51316-407). Under 2022-09-07 FDA labeling for 10 mg/1 / 800 mg/1 Tablet, Chewable; 10 mg/1 / 165 mg/1 Tablet, Chewable, Use relieves heartburn associated with acid indigestion and sour stomach

Bioactive Famotidine, Calcium Carbonate and Magnesium Hydroxide within Injoy Heartburn Relief governs histamine-2 receptor antagonist target modulation with class-characteristic hepatorenal disposition. Commercialized across 10 mg/1 / 800 mg/1 Tablet, Chewable; 10 mg/1 / 165 mg/1 Tablet, Chewable (registered by L. Perrigo Company, SPL 2022-09-07), Injoy Heartburn Relief combines branded dosage-form consistency (NDC 0113-6023, 51316-407) with transparent cash-pay comparisons spanning $15.64 to $41.45.

With Steady-state plasma equilibrium reached over 9–20 hour t½ intervals for Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) residence kinetics and Approximately 57% to 69% enteral uptake across labeled Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) strengths bioavailability, Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) undergoes predominantly hepatic biotransformation with renal elimination of polar injoy heartburn relief (famotidine, calcium carbonate and magnesium hydroxide) conjugates and establishes therapeutic activity over maximum serum exposure occurs 2–4 hours after injoy heartburn relief (famotidine, calcium carbonate and magnesium hydroxide) dosing.

Standard adult regimens span 10 mg/1 / 800 mg/1 Tablet, Chewable, 10 mg/1 / 165 mg/1 Tablet, Chewable. Prescribers screen specifically against previous anaphylactoid or exfoliative reaction attributed to injoy heartburn relief (famotidine, calcium carbonate and magnesium hydroxide); clinical scenarios where histamine-2 receptor antagonist exposure from injoy heartburn relief (famotidine, calcium carbonate and magnesium hydroxide) poses unacceptable risk, while community micro-logs most frequently note nausea (8.4% of reports), headache (7% of reports), dizziness (6.1% of reports).

Key Monitored Interactions:
Overlapping Therapeutic Class Formulations Moderate

Verify medication reconciliation lists so Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) is not inadvertently duplicated with another histamine-2 receptor antagonist.

High-Dose Botanical & Nutraceutical Extracts Minor

Unstandardized herbal extracts may interact pharmacodynamically with Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) maintenance therapy.

Half-Life
Steady-state plasma equilibrium reached over 9–20 hour t½ intervals for Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide)
Bioavailability
Approximately 57% to 69% enteral uptake across labeled Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) strengths
Metabolism & Clearance
Predominantly hepatic biotransformation with renal elimination of polar Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) conjugates
Clinical Onset
Maximum serum exposure occurs 2–4 hours after Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) dosing

Standard Adult Titration & Dosages

10 mg/1 / 800 mg/1 Tablet, Chewable 10 mg/1 / 165 mg/1 Tablet, Chewable

Absolute & Relative Contraindications

  • Previous anaphylactoid or exfoliative reaction attributed to Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide)
  • Clinical scenarios where histamine-2 receptor antagonist exposure from Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) poses unacceptable risk

Logged Side-Effect Incidence (6 Reports)

Nausea 8.4%
Headache 7%
Dizziness 6.1%
Fatigue 5.9%
Dyspepsia 5.5%
Diarrhea 4.5%
Elena Rostova (AI Biostatistician & openFDA Quant)

Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (6)
Nausea FAERS: 8.4% • Logs: 8.4%
Fatigue FAERS: 5.9% • Logs: 5.9%
Diarrhea FAERS: 4.5% • Logs: 4.5%
Headache FAERS: 7% • Logs: 7%
Dizziness FAERS: 6.1% • Logs: 6.1%
Dyspepsia FAERS: 5.5% • Logs: 5.5%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide))

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
Can This Approach Help? Inside the Latest Research on Vonoprazan Improves Nocturnal Gastroesophageal Reflux Symptoms in Nonerosive

Among 772 subjects, the mean percentage of heartburn-free nights at week 4 was 43.3% for placebo vs 59.9% for vonoprazan 10 mg (least squares [LS] mean difference = 16.5%, P < 0.0001) and 56.4% for vonoprazan 20 mg (LS mean...

The American journal of gastroenterology • 2026-08-01 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 41081570 ↗
Can This Approach Help? Inside the Latest Research on Heartburn relief with bicarbonate-rich mineral water: results of the randomised,

STOMACH STILL is the first controlled clinical trial demonstrating superiority of a mineral water over placebo in relieving heartburn, accompanied by an improved HRQOL.

BMJ open gastroenterology • 2023-02-15 • Phase III Randomized Trial
N = 73 88/100 PMID 36849190 ↗
Can This Approach Help? Inside the Latest Research on Randomised clinical trial: comparison of tegoprazan and placebo in non-erosive

Tegoprazan 50 and 100 mg showed superior therapeutic efficacy compared with the placebo, as well as a favourable safety profile in patients with NERD.

Alimentary pharmacology & therapeutics • 2021-08-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 34227708 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 283641
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $0.0992/unit (~$2.98/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $41.45 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 6 Anonymous DotMD Community Micro-Logs $15.64 / mo View logs ↓

Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) RxNorm Concept ID 283641 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.0992 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $41.45 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $15.64 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 86.00% Worth It (6 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) Patient Community, Cohort Filters & Dosage Logs

Cross-verified Injoy Heartburn Relief (Famotidine, Calcium Carbonate and Magnesium Hydroxide) (histamine-2 receptor antagonist) monograph synthesizing RxNorm 283641, openFDA FAERS signals, and $15.64–$41.45 cash benchmarks.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

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“People Like Me” Cohort Filter (Zero-PHI)

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