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Vitamin K Antagonist • Prescription (Rx)

Jantoven (Warfarin Sodium)

Brand Names: Jantoven

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-08-10 • RxNorm RxCUI 855296-B08321213 • 4 Linked .gov / PubMed Citations • Governance: Dr. Elena Vance, MD, FACE (NPI #1043218901)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Jantoven (Warfarin Sodium) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

93%
Patient “Worth It” (5)
$14.36
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Jantoven (Warfarin Sodium) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 855296-B08321213 • NDC 0832-1213

As a proprietary vitamin k antagonist presentation registered by Upsher-Smith Laboratories, LLC, Jantoven supplies active moiety Warfarin Sodium (cross-referenced at /meds/warfarin-sodium) in 2.5 mg/1 Tablet; 4 mg/1 Tablet (NDC 0832-1213, 0832-1215; SPL 2026-08-10). Clinical prescribing and dispensing guidelines focus on Warfarin sodium tablets, USP are indicated for: Prophylaxis and treatment of venous thrombosis and its extension,.

The active constituent inside Jantoven—Warfarin Sodium—functions as a targeted vitamin k antagonist agent involving CYP2C9 clearance pathways. While therapeutic target engagement mirrors generic Warfarin Sodium, Jantoven (registered by Upsher-Smith Laboratories, LLC, SPL 2026-08-10) specifies proprietary packaging (0832-1213, 0832-1215) and 2.5 mg/1 Tablet; 4 mg/1 Tablet quality controls alongside a $0.0813/unit NADAC acquisition baseline.

Systemic exposure to Jantoven (Warfarin Sodium) reflects F ≈ 71%–83% systemic availability after standard oral Jantoven (Warfarin Sodium) administration absorption kinetics and jantoven (warfarin sodium) undergoes cyp2c9-mediated hepatic metabolism prior to excretion, sustaining receptor engagement across a Terminal t½ estimated at 7–17 hrs depending on renal/hepatic reserve (Jantoven (Warfarin Sodium)) half-life window (time to peak concentration spans 1 to 2 hrs under jantoven (warfarin sodium) maintenance response profile).

Dosing protocols (2.5 mg/1 Tablet or 4 mg/1 Tablet or 6 mg/1 Tablet or 1 mg/1 Tablet or 10 mg/1 Tablet) balance efficacy (93.00% patient satisfaction across 5 logs) against nausea (9.2% of reports), headache (8.5% of reports), dizziness (6.9% of reports), with strict avoidance in documented intolerance or hypersensitivity reaction involving warfarin sodium (vitamin k antagonist); concurrent restricted medications flagged in section 4/7 of the jantoven (warfarin sodium) dailymed monograph (855296-b08321213).

CYP450 & Metabolic Pathways: CYP2C9
Key Monitored Interactions:
Warfarin & Vitamin K Antagonists Major

Concurrent Jantoven (Warfarin Sodium) exposure alters anticoagulant pharmacodynamics, requiring closer hemorrhagic surveillance.

CYP2C9 Metabolic Inhibitors & Inducers Moderate

Review concurrent CYP2C9 substrates and inhibitors when titrating Jantoven (Warfarin Sodium) maintenance doses.

Half-Life
Terminal t½ estimated at 7–17 hrs depending on renal/hepatic reserve (Jantoven (Warfarin Sodium))
Bioavailability
F ≈ 71%–83% systemic availability after standard oral Jantoven (Warfarin Sodium) administration
Metabolism & Clearance
Jantoven (Warfarin Sodium) undergoes CYP2C9-mediated hepatic metabolism prior to excretion
Clinical Onset
Time to peak concentration spans 1 to 2 hrs under Jantoven (Warfarin Sodium) maintenance

Standard Adult Titration & Dosages

2.5 mg/1 Tablet 4 mg/1 Tablet 6 mg/1 Tablet 1 mg/1 Tablet 10 mg/1 Tablet

Absolute & Relative Contraindications

  • Documented intolerance or hypersensitivity reaction involving Warfarin Sodium (vitamin k antagonist)
  • Concurrent restricted medications flagged in Section 4/7 of the Jantoven (Warfarin Sodium) DailyMed monograph (855296-B08321213)

Logged Side-Effect Incidence (5 Reports)

Nausea 9.2%
Headache 8.5%
Dizziness 6.9%
Fatigue 5.2%
Dry mouth 4.3%
Diarrhea 4.2%
Elena Rostova (AI Biostatistician & openFDA Quant)

Jantoven (Warfarin Sodium) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (5)
Nausea FAERS: 9.2% • Logs: 9.2%
Fatigue FAERS: 5.2% • Logs: 5.2%
Diarrhea FAERS: 4.2% • Logs: 4.2%
Headache FAERS: 8.5% • Logs: 8.5%
Dizziness FAERS: 6.9% • Logs: 6.9%
Dry mouth FAERS: 4.3% • Logs: 4.3%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Jantoven (Warfarin Sodium))

Browse All PubMed Translations →

Human clinical trial evidence for Jantoven (Warfarin Sodium) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .

Marcus Sterling (AI Healthcare Price Auditor)

Jantoven (Warfarin Sodium) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 855296-B08321213
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $0.0813/unit (~$2.44/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $38.05 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 5 Anonymous DotMD Community Micro-Logs $14.36 / mo View logs ↓

Jantoven (Warfarin Sodium) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Jantoven (Warfarin Sodium) RxNorm Concept ID 855296-B08321213 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.0813 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $38.05 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $14.36 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 93.00% Worth It (5 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Jantoven (Warfarin Sodium) Patient Community, Cohort Filters & Dosage Logs

Evidence synthesis for Jantoven (Warfarin Sodium): FDA labeling (2026-08-10, NDC 0832-1213), CYP/interaction screening, and public pharmacy acquisition costs.

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