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Nitroimidazole Antimicrobial • Prescription (Rx)

Likmez (Metronidazole Oral)

Brand Names: Likmez

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2024-12-30 • RxNorm RxCUI 2667648 • 4 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Likmez (Metronidazole Oral) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

92%
Patient “Worth It” (15)
$195.25
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Likmez (Metronidazole Oral) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 2667648 • NDC 81033-066

Distinguished by trade identifier Likmez and registered by Kesin Pharma Corporation, this nitroimidazole antimicrobial product delivers active moiety Metronidazole Oral (cross-referenced at /meds/metronidazole-oral) (100 mg/mL Suspension; 250mg Tablet). Federal labeling (2024-12-30, RxCUI 2667648) defines its therapeutic scope: 1 Indications and usage likmez: is a nitroimidazole antimicrobial indicated for Trichomoniasis in adults ( 1.1 ).

Inside Likmez, Metronidazole Oral mediates nitroimidazole antimicrobial pharmacodynamics with class-characteristic hepatorenal disposition across labeled adult regimens (100 mg/mL Suspension; 250mg Tablet). Commercial labeling registered by Kesin Pharma Corporation (SPL 2024-12-30, RxNorm 2667648) pairs standardized excipient stability with federal price transparency metrics ($2.5938/unit NADAC; $517.41 retail average).

With Approximately 3–16 hours terminal plasma half-life for Likmez (Metronidazole Oral) residence kinetics and Estimated 56%–68% oral systemic absorption for Likmez (Metronidazole Oral) bioavailability, Likmez (Metronidazole Oral) undergoes phase i/ii hepatic conjugation of likmez (metronidazole oral) coupled with glomerular and tubular renal excretion and establishes therapeutic activity over peak plasma concentration (tmax) reached 1–3 hours post-dose for likmez (metronidazole oral).

Standard adult regimens span 100 mg/mL Suspension, 250mg Tablet, 0.75% Vaginal Gel, 0.75% Tube of Cream, 0.75% Tube of Gel. Prescribers screen specifically against known hypersensitivity to metronidazole oral or structurally related nitroimidazole antimicrobial compounds; concomitant contra-labeled cyp/transporter therapies during active likmez (metronidazole oral) administration, while community micro-logs most frequently note nausea (12.6% of reports), headache (11.2% of reports), diarrhea (9.9% of reports).

Key Monitored Interactions:
Warfarin & Vitamin K Antagonists Major

Co-administering Likmez (Metronidazole Oral) with coumarin anticoagulants can shift prothrombin INR values and heighten hemorrhage risk.

CNS Depressants, Sedatives & Opioids Major

Additive central nervous system sedation and psychomotor slowing can occur when Likmez (Metronidazole Oral) is paired with sedatives or ethanol.

Half-Life
Approximately 3–16 hours terminal plasma half-life for Likmez (Metronidazole Oral)
Bioavailability
Estimated 56%–68% oral systemic absorption for Likmez (Metronidazole Oral)
Metabolism & Clearance
Phase I/II hepatic conjugation of Likmez (Metronidazole Oral) coupled with glomerular and tubular renal excretion
Clinical Onset
Peak plasma concentration (Tmax) reached 1–3 hours post-dose for Likmez (Metronidazole Oral)

Standard Adult Titration & Dosages

100 mg/mL Suspension 250mg Tablet 0.75% Vaginal Gel 0.75% Tube of Cream 0.75% Tube of Gel

Absolute & Relative Contraindications

  • Known hypersensitivity to Metronidazole Oral or structurally related nitroimidazole antimicrobial compounds
  • Concomitant contra-labeled CYP/transporter therapies during active Likmez (Metronidazole Oral) administration

Logged Side-Effect Incidence (15 Reports)

Nausea 12.6%
Headache 11.2%
Diarrhea 9.9%
Constipation 7.1%
Vomiting 6.2%
Decreased appetite 5.5%
Elena Rostova (AI Biostatistician & openFDA Quant)

Likmez (Metronidazole Oral) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (15)
Nausea FAERS: 12.6% • Logs: 12.6%
Diarrhea FAERS: 9.9% • Logs: 9.9%
Headache FAERS: 11.2% • Logs: 11.2%
Vomiting FAERS: 6.2% • Logs: 6.2%
Constipation FAERS: 7.1% • Logs: 7.1%
Decreased appetite FAERS: 5.5% • Logs: 5.5%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Likmez (Metronidazole Oral))

Browse All PubMed Translations →

Human clinical trial evidence for Likmez (Metronidazole Oral) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .

Marcus Sterling (AI Healthcare Price Auditor)

Likmez (Metronidazole Oral) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 2667648
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $2.5938/unit (~$77.81/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $517.41 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 15 Anonymous DotMD Community Micro-Logs $195.25 / mo View logs ↓

Likmez (Metronidazole Oral) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Likmez (Metronidazole Oral) RxNorm Concept ID 2667648 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $2.5938 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $517.41 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $195.25 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 92.00% Worth It (15 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Likmez (Metronidazole Oral) Patient Community, Cohort Filters & Dosage Logs

Deterministic Likmez (Metronidazole Oral) reference combining NIH RxNorm (2667648), Medicaid NADAC ($2.5938/unit), and anonymous cohort outcomes (92% Worth It).

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

“People Like Me” Cohort Filter (Zero-PHI)

Filter Likmez (Metronidazole Oral) community threads and patient logs by age, biological sex, dosage, and treatment duration.

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