Effectiveness: 5/5 • Worth It
Dosage: 0.6 mg SC daily • Paid: $184.80/mo
via TeleMed
Nausea
Switched to TeleMed at 0.6 mg SC daily for Liraglutide; monthly out-of-pocket dropped to $184.80 compared with $589.00 retail.
Daily Acylated GLP-1 Receptor Agonist • Rx
Liraglutide
Brand Reference: Victoza, Saxenda
Medically Reviewed by Dr. Elena Vance, MD, FACE (NPI #1043218901)
78.20%
Patient “Worth It”
16 verified logs
$210.00
Lowest Monthly Cash
Liraglutide Clinical & Real-World Cost Fact Matrix
| Metric | Verified Benchmark | Source |
|---|---|---|
| Liraglutide RxNorm Concept ID | 475968 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $18.6400 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $589.00 / mo | CMS NADAC + U.S. Retail Markup Index |
| Mark Cuban Cost Plus Wholesale Price | $165.00 / mo (Direct TeleMed) | Direct Telehealth Formulary |
| Community Mean Out-of-Pocket Paid | $210.00 / mo | 16 Zero-PHI Verified Patient Logs |
INSTANT PRESCRIPTION & CASH ROUTING
DotMD Club Members get $29 flat-rate script renewals →
Verified Online Prescribers & Wholesale Pharmacies for Liraglutide
Ro Body & Metabolic Clinic (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~2 days
$
45.00
Consult / Starting Tier
AgelessRx Geroprotective Telehealth (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~3 days
• Rx included in monthly tier
$
65.00
All-In Monthly
Midi Health Perimenopause & HRT Clinic (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~2 days
$
59.00
Consult / Starting Tier
Hims & Hers Direct Cash Pharmacy (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~2 days
• Rx included in monthly tier
$
49.00
All-In Monthly
Liraglutide Clinical Pharmacology & DailyMed Monograph
RxCUI 475968 • NDC 00169-4060-13
FDA Boxed Warning (Liraglutide):
Thyroid C-cell tumor risk; contraindicated in patients with MTC or MEN 2.
Palmitoyl-acylated GLP-1 analogue that reversibly binds plasma albumin to resist DPP-4 degradation, activating cyclic AMP via Gs-coupled GLP-1 receptors on pancreatic beta cells and paraventricular hypothalamic satiety neurons.
CMS National Average Drug Acquisition Cost (NADAC) tracking places Liraglutide (Victoza / Saxenda, RxCUI 475968) at $18.6400 per unit, whereas walk-in chain pharmacies bill cash patients an average of $589.00 monthly—creating a 64% ($379.00/mo) wholesale arbitrage spread down to $210.00.
Systemic exposure to Liraglutide reflects 55% subcutaneous absorption kinetics and ubiquitous endopeptidase cleavage without single-organ predominance, sustaining receptor engagement across a 13 hours half-life window (8–12 hours to cmax response profile).
Dosing protocols (0.6 mg SC daily or 1.2 mg SC daily or 1.8 mg SC daily or 3.0 mg SC daily) balance efficacy (78.20% patient satisfaction across 16 logs) against nausea (38% of reports), diarrhea (17% of reports), dyspepsia (14% of reports), with strict avoidance in medullary thyroid carcinoma; men 2; pregnancy during weight-management dosing.
Half-Life
13 hours
Bioavailability
55% subcutaneous
Metabolism & Clearance
Ubiquitous endopeptidase cleavage without single-organ predominance
Clinical Onset
8–12 hours to Cmax
Standard Adult Titration & Dosages
0.6 mg SC daily 1.2 mg SC daily 1.8 mg SC daily 3.0 mg SC daily
Absolute & Relative Contraindications
- Medullary thyroid carcinoma
- MEN 2
- Pregnancy during weight-management dosing
Logged Side-Effect Incidence (16 Reports)
Nausea 38%
Diarrhea 17%
Dyspepsia 14%
Liraglutide Patient Dosage Logs & Out-of-Pocket Cost Ledger
Across 16 verified cash-pay logs, Liraglutide achieves a 78.20% Worth-It rating with out-of-pocket spend averaging $210.00/mo versus $589.00/mo walk-in retail.
15-Second Anonymous Micro-Log (Zero-PHI Architecture)
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Effectiveness: 5/5 • Worth It
Dosage: 1.2 mg SC daily • Paid: $214.20/mo
via Compounding
Completed 10 weeks on Liraglutide (1.2 mg SC daily). Zero notable side effects on steady dosing.
Effectiveness: 4/5 • Not Worth It
Dosage: 1.8 mg SC daily • Paid: $243.60/mo
via Cash Clinic
Dyspepsia
Consistent biomarker response on 1.8 mg SC daily Liraglutide sourced via Cash Clinic ($243.60/mo cash pay without insurance prior authorization).