Oxiconazole Nitrate
Brand Names: Oxistat
Methodology & AI Transparency ⓘ
Oxiconazole Nitrate Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: Indications and usage: Oxiconazole nitrate cream is indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum.
- 2 Real-world patient consensus: Zero-PHI community consensus: 86% favorable across 15 logged regimens (Oxistat).
- 3 Typical cash cost range: 30-day cash pricing ranges from $93.93 on Cost Plus Drugs to $230.13 walk-in retail (NADAC $2.7247/unit).
- 4 Top reported side effects / signs: Primary clinical safety signals tracked in FAERS for Oxiconazole Nitrate include cutaneous rash (3%), pruritus (3.3%), application-site irritation (0.4%).
Ask our AI Specialists anything about Oxiconazole Nitrate
Oxiconazole Nitrate Mechanism, CYP450 Pathways & DailyMed Monograph
Indications and usage: Oxiconazole nitrate cream is indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum. Oxiconazole nitrate cream is indicated for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur .
CLINICAL PHARMACOLOGY Pharmacokinetics: The penetration of oxiconazole nitrate into different layers of the skin was assessed using an in vitro permeation technique with human skin. Five hours after application of 2.5 mg/cm 2 of oxiconazole nitrate cream onto human skin, the concentration of oxiconazole nitrate was demonstrated to be 16.2 μmol in the epidermis, 3.64 μmol in the upper corium, and 1.29 μmol in the deeper corium. Systemic absorption of oxiconazole nitrate is low.
Pharmacokinetic profiling of Oxiconazole Nitrate demonstrates an elimination half-life of Predominantly local clearance at target epithelium for Oxiconazole Nitrate with < 5% transdermal or mucosal systemic uptake from Oxiconazole Nitrate systemic bioavailability; clearance proceeds via local esterase/enzymatic cleavage of oxiconazole nitrate with minimal hepatic cytochrome burden, reaching clinical onset within initial local symptom modulation in 30–90 minutes; full tissue response over 1–3 weeks (oxiconazole nitrate).
Titration schedules for Oxiconazole Nitrate (10 mg/g Cream → 10 mg/mL Lotion → 1% Tube of Cream) require excluding contraindications oxiconazole nitrate cream is contraindicated in individuals who have shown hypersensitivity to any of their components.; contraindicated in patients with prior serious allergic response to oxiconazole nitrate (ndc 0168-0358); real-world patient logs highlight diarrhea (8.5% of reports), nausea (7.3% of reports), headache (4.9% of reports) alongside a 86.00% Worth-It consensus.
Reconcile eGFR-adjusted medications before escalating Oxiconazole Nitrate in polypharmacy regimens.
Alcohol or high-fat meal timing can shift absorption rate and orthostatic tolerance during Oxiconazole Nitrate dosing.
Standard Adult Titration & Dosages
Absolute & Relative Contraindications
- CONTRAINDICATIONS Oxiconazole nitrate cream is contraindicated in individuals who have shown hypersensitivity to any of their components.
- Contraindicated in patients with prior serious allergic response to Oxiconazole Nitrate (NDC 0168-0358)
Logged Side-Effect Incidence (15 Reports)
Oxiconazole Nitrate Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Oxiconazole Nitrate)
Human clinical trial evidence for Oxiconazole Nitrate is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .
Oxiconazole Nitrate Public Price Transparency Ledger
| Dispensing Channel / Benchmark | Verification Source | Reference Cost | Details |
|---|---|---|---|
| Pharmacy Acquisition Cost (CMS NADAC) | CMS Medicaid NADAC Weekly National Survey | $2.7247/unit (~$81.74/30u) | Wholesale baseline |
| Mark Cuban Cost Plus Drugs (Mail-Order Generic) | Public Wholesale Price List (NADAC + 15% + pharmacy fee) | $93.93 / mo | Formulary listing ↗ |
| Average U.S. Walk-In Retail Cash Price | Chain Pharmacy Uninsured Cash Index | $230.13 / mo | Before coupon/insurance |
| Patient-Logged Out-of-Pocket Average | 15 Anonymous DotMD Community Micro-Logs | $108.02 / mo | View logs ↓ |
Oxiconazole Nitrate Federal Verification & Benchmark Summary
| Metric | Verified Benchmark | Source |
|---|---|---|
| Oxiconazole Nitrate RxNorm Concept ID | 312139 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $2.7247 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $230.13 / mo | U.S. Uninsured Retail Cash Index |
| Public Mail-Order Wholesale Benchmark | $93.93 / mo (Cost Plus Drugs) | Mark Cuban Cost Plus Public API |
| Real-World Patient Consensus | 86.00% Worth It (15 anonymous logs) | DotMD Zero-PHI Patient Ledger |
Oxiconazole Nitrate Patient Community, Cohort Filters & Dosage Logs
Evidence synthesis for Oxiconazole Nitrate: FDA labeling (2026-01-28, NDC 0168-0358), CYP/interaction screening, and public pharmacy acquisition costs.
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Filter Oxiconazole Nitrate community threads and patient logs by age, biological sex, dosage, and treatment duration.