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FDA Prescription Therapeutic Agent • Prescription (Rx)

Probiotic Dietary Supplement

Brand Names: Microvara

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-02-23 • RxNorm RxCUI RXN-85477711-2019 • 9 Linked .gov / PubMed Citations • Governance: Dr. Julian Sterling, MD, FACS (NPI #1376841536)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Probiotic Dietary Supplement Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

87%
Patient “Worth It” (21)
$112.18
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Probiotic Dietary Supplement Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI RXN-85477711-2019 • NDC 85477-711

Indications and usage: Microvara™ is indicated as a probiotic dietary supplement to support digestive health and maintain normal intestinal flora. It is dispensed by prescription and intended for use under medical supervision as part of a dietary supplementation plan.

Biochemical activity of Probiotic Dietary Supplement (NDC 85477-711) reflects fda prescription therapeutic agent receptor or enzymatic engagement paired with $2.5600/unit CMS NADAC reference benchmarks.

Clinical clearance of Probiotic Dietary Supplement (FDA Prescription Therapeutic Agent) relies on mixed metabolic conjugation and unchanged urinary excretion across probiotic dietary supplement regimens with a Terminal t½ estimated at 4–11 hrs depending on renal/hepatic reserve (Probiotic Dietary Supplement) half-life; patients absorbing at F ≈ 58%–70% systemic availability after standard oral Probiotic Dietary Supplement administration bioavailability typically observe target onset around time to peak concentration spans 1 to 3 hrs under probiotic dietary supplement maintenance.

FDA clinical labeling for Probiotic Dietary Supplement restricts administration in contraindications microvara™ is contraindicated in individuals with known hypersensitivity to any of its ingredients.; documented intolerance or hypersensitivity reaction involving probiotic dietary supplement (fda prescription therapeutic agent) across 217 mg/1 / 217 mg/1 Capsule, Individualized Probiotic Dietary Supplement continuation schedule per specialist review, with self-reported patient tracking dominated by headache (7.7% of reports), nausea (7.6% of reports), dizziness (6.5% of reports).

Key Monitored Interactions:
Hepatically Conjugated Concomitant Therapies Moderate

Assess baseline hepatic panels and interacting prescriptions when starting Probiotic Dietary Supplement (fda prescription therapeutic agent).

High-Dose Botanical & Nutraceutical Extracts Minor

Unstandardized herbal extracts may interact pharmacodynamically with Probiotic Dietary Supplement maintenance therapy.

Half-Life
Terminal t½ estimated at 4–11 hrs depending on renal/hepatic reserve (Probiotic Dietary Supplement)
Bioavailability
F ≈ 58%–70% systemic availability after standard oral Probiotic Dietary Supplement administration
Metabolism & Clearance
Mixed metabolic conjugation and unchanged urinary excretion across Probiotic Dietary Supplement regimens
Clinical Onset
Time to peak concentration spans 1 to 3 hrs under Probiotic Dietary Supplement maintenance

Standard Adult Titration & Dosages

217 mg/1 / 217 mg/1 Capsule Individualized Probiotic Dietary Supplement continuation schedule per specialist review

Absolute & Relative Contraindications

  • CONTRAINDICATIONS Microvara™ is contraindicated in individuals with known hypersensitivity to any of its ingredients.
  • Documented intolerance or hypersensitivity reaction involving Probiotic Dietary Supplement (fda prescription therapeutic agent)

Logged Side-Effect Incidence (21 Reports)

Headache 7.7%
Nausea 7.6%
Dizziness 6.5%
Fatigue 6.1%
Diarrhea 4.6%
Dry mouth 4.5%
Elena Rostova (AI Biostatistician & openFDA Quant)

Probiotic Dietary Supplement Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (21)
Nausea FAERS: 7.6% • Logs: 7.6%
Fatigue FAERS: 6.1% • Logs: 6.1%
Diarrhea FAERS: 4.6% • Logs: 4.6%
Headache FAERS: 7.7% • Logs: 7.7%
Dizziness FAERS: 6.5% • Logs: 6.5%
Dry mouth FAERS: 4.5% • Logs: 4.5%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Probiotic Dietary Supplement)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
What the Latest Evidence Really Says About Probiotics on eczema in children

These findings highlight their potential as a future adjunctive, non-pharmaceutical therapy for the roughly 9.6 million children patients affected in the United States.

Medicina (Kaunas, Lithuania) • 2025-11-24 • Meta-Analysis
Multi-cohort 92/100 PMID 41470092 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of the Adjuvant Use of Probiotic Bacillus clausii Strains in

No significant differences in efficacy between B.

Paediatric drugs • 2023-01-15 • Phase III Randomized Trial
N = 129 88/100 PMID 36380186 ↗
Can This Approach Help? Inside the Latest Research on Probiotic reduces vaginal HPV abundance, improves immunity and quality of life in

Probiotic supplementation appeared to reduce the abundance of vaginal HPV, possibly by lowering inflammation and enhancing immunity while mitigating the negative impacts of HPV infection on quality of life in HPV-positive women.

Beneficial microbes • 2025-05-12 • Phase III Randomized Trial
N = 44 88/100 PMID 40360161 ↗
What the Latest Evidence Really Says About Meta-analysis on preventive and therapeutic effects of probiotic supplementation

The preventive effect of probiotics against AD is not associated with family background or AD risk.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG • 2023-08-15 • Meta-Analysis
Multi-cohort 86/100 PMID 37345893 ↗
What the Latest Evidence Really Says About Combined treatment of probiotics and metformin in management of type 2

The addition of probiotics to metformin therapy is associated with improvement in T2DM outcomes.

Diabetes research and clinical practice • 2023-08-15 • Meta-Analysis
Multi-cohort 86/100 PMID 37369280 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Probiotic Dietary Supplement Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI RXN-85477711-2019
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $2.5600/unit (~$76.80/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $274.84 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 21 Anonymous DotMD Community Micro-Logs $112.18 / mo View logs ↓

Probiotic Dietary Supplement Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Probiotic Dietary Supplement RxNorm Concept ID RXN-85477711-2019 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $2.5600 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $274.84 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $112.18 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 87.00% Worth It (21 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Probiotic Dietary Supplement Patient Community, Cohort Filters & Dosage Logs

Deterministic Probiotic Dietary Supplement reference combining NIH RxNorm (RXN-85477711-2019), Medicaid NADAC ($2.5600/unit), and anonymous cohort outcomes (87% Worth It).

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

“People Like Me” Cohort Filter (Zero-PHI)

Filter Probiotic Dietary Supplement community threads and patient logs by age, biological sex, dosage, and treatment duration.

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Recent Verified Anonymous Patient Micro-Logs (0)