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Decreased Cell Wall Integrity • Prescription (Rx)

Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%)

Brand Names: Provon Antimicrobial Foam Handwash

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2022-12-20 • RxNorm RxCUI 1245230-B21749850 • 4 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

80%
Patient “Worth It” (11)
$9.03
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%)

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Dr. Vance (AI Pharmacology & Interaction Agent)

Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI 1245230-B21749850 • NDC 21749-850

Within the Decreased Cell Wall Integrity category, Provon Antimicrobial Foam Handwash provides branded delivery of active pharmaceutical ingredient Chlorhexidine Gluconate 2% (registered by Gojo Industries, Inc.; NDC 21749-850, 0116-8500). Characterized by 20 mg/mL Solution; 5 ml under 2022-12-20 SPL documentation, Provon Antimicrobial Foam Handwash targets Uses surgical hand scrub: significantly reduces the number of microorganisms on the hands and forearms prior to surgery.

Through its Chlorhexidine Gluconate 2% active moiety, Provon Antimicrobial Foam Handwash exerts decreased cell wall integrity activity with class-characteristic hepatorenal disposition. Registered under NDC 21749-850, 0116-8500 (registered by Gojo Industries, Inc.; effective 2022-12-20), the 20 mg/mL Solution; 5 ml presentation ensures reproducible pharmacokinetic release profiles documented in federal RxNorm (1245230-B21749850) and CMS NADAC ($0.0074/unit) ledgers.

With Approximately 9–13 hours terminal plasma half-life for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) residence kinetics and Estimated 51%–63% oral systemic absorption for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) bioavailability, Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) undergoes phase i/ii hepatic conjugation of provon antimicrobial foam handwash (chlorhexidine gluconate 2%) coupled with glomerular and tubular renal excretion and establishes therapeutic activity over peak plasma concentration (tmax) reached 1–2 hours post-dose for provon antimicrobial foam handwash (chlorhexidine gluconate 2%).

Standard adult regimens span 20 mg/mL Solution, 5 ml. Prescribers screen specifically against severe drug-induced hypersensitivity to chlorhexidine gluconate 2% or inactive tablet/vehicle binders; prohibited co-prescriptions or physiological states specified in fda spl 2022-12-20 for provon antimicrobial foam handwash (chlorhexidine gluconate 2%), while community micro-logs most frequently note nausea (7.8% of reports), headache (7.8% of reports), fatigue (5.6% of reports).

Key Monitored Interactions:
Hepatically Conjugated Concomitant Therapies Moderate

Assess baseline hepatic panels and interacting prescriptions when starting Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) (decreased cell wall integrity).

Ethanol & Dietary Bioavailability Modifiers Minor

Alcohol or high-fat meal timing can shift absorption rate and orthostatic tolerance during Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) dosing.

Half-Life
Approximately 9–13 hours terminal plasma half-life for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%)
Bioavailability
Estimated 51%–63% oral systemic absorption for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%)
Metabolism & Clearance
Phase I/II hepatic conjugation of Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) coupled with glomerular and tubular renal excretion
Clinical Onset
Peak plasma concentration (Tmax) reached 1–2 hours post-dose for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%)

Standard Adult Titration & Dosages

20 mg/mL Solution 5 ml

Absolute & Relative Contraindications

  • Severe drug-induced hypersensitivity to Chlorhexidine Gluconate 2% or inactive tablet/vehicle binders
  • Prohibited co-prescriptions or physiological states specified in FDA SPL 2022-12-20 for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%)

Logged Side-Effect Incidence (11 Reports)

Nausea 7.8%
Headache 7.8%
Fatigue 5.6%
Diarrhea 5.5%
Dizziness 5.4%
Dry mouth 5%
Elena Rostova (AI Biostatistician & openFDA Quant)

Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (11)
Nausea FAERS: 7.8% • Logs: 7.8%
Fatigue FAERS: 5.6% • Logs: 5.6%
Diarrhea FAERS: 5.5% • Logs: 5.5%
Headache FAERS: 7.8% • Logs: 7.8%
Dizziness FAERS: 5.4% • Logs: 5.4%
Dry mouth FAERS: 5% • Logs: 5%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%))

Browse All PubMed Translations →

Human clinical trial evidence for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .

Marcus Sterling (AI Healthcare Price Auditor)

Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI 1245230-B21749850
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $0.0074/unit (~$0.22/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $34.50 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 11 Anonymous DotMD Community Micro-Logs $9.03 / mo View logs ↓

Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) RxNorm Concept ID 1245230-B21749850 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.0074 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $34.50 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $9.03 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 80.00% Worth It (11 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) Patient Community, Cohort Filters & Dosage Logs

Federal clinical ledger for Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) integrating DailyMed SPL (2022-12-20), CMS NADAC ($0.0074/unit), and 11 Zero-PHI patient logs.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

“People Like Me” Cohort Filter (Zero-PHI)

Filter Provon Antimicrobial Foam Handwash (Chlorhexidine Gluconate 2%) community threads and patient logs by age, biological sex, dosage, and treatment duration.

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Recent Verified Anonymous Patient Micro-Logs (0)