Brand Reference: Viagra, Revatio
| Metric | Verified Benchmark | Source |
|---|---|---|
| Sildenafil Citrate RxNorm Concept ID | 966571 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.0540 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $138.00 / mo | CMS NADAC + U.S. Retail Markup Index |
| Mark Cuban Cost Plus Wholesale Price | $5.40 / mo | Cost Plus Drugs Wholesale Feed |
| Community Mean Out-of-Pocket Paid | $6.80 / mo | 52 Zero-PHI Verified Patient Logs |
Blocks PDE5-catalyzed hydrolysis of NO-stimulated cGMP inside cavernosal smooth muscle, decreasing intracellular Ca2+ to dilate helicine arteries and compress subtunical venules during sexual arousal.
CMS National Average Drug Acquisition Cost (NADAC) tracking places Sildenafil Citrate (Viagra / Revatio, RxCUI 966571) at $0.0540 per unit, whereas walk-in chain pharmacies bill cash patients an average of $138.00 monthly—creating a 96% ($132.60/mo) wholesale arbitrage spread down to $5.40.
Systemic exposure to Sildenafil Citrate reflects 41% fasting oral (high-fat meal delays Tmax by 60 min and cuts Cmax 29%) absorption kinetics and hepatic cyp3a4 (major) and cyp2c9 n-demethylation to active uk-103,320, sustaining receptor engagement across a 3–4 hours half-life window (30–45 minutes fasting response profile).
Dosing protocols (20 mg PO (generic Revatio tablet arbitrage: 1–5 tabs PRN) or 50 mg PO 1 hour pre-activity or 100 mg PO PRN) balance efficacy (91.40% patient satisfaction across 52 logs) against facial flushing (19% of reports), nasal stuffiness (15% of reports), transient blue-cyan pde6 tint (6% of reports), with strict avoidance in organic nitrates or amyl/butyl nitrites; riociguat co-administration; hereditary retinitis pigmentosa.
Across 52 verified cash-pay logs, Sildenafil Citrate achieves a 91.40% Worth-It rating with out-of-pocket spend averaging $6.80/mo versus $138.00/mo walk-in retail.
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Switched to Cost Plus Drugs at 20 mg PO (generic Revatio tablet arbitrage: 1–5 tabs PRN) for Sildenafil Citrate; monthly out-of-pocket dropped to $4.75 compared with $138.00 retail.
Completed 10 weeks on Sildenafil Citrate (50 mg PO 1 hour pre-activity). Zero notable side effects on steady dosing.
Consistent biomarker response on 100 mg PO PRN Sildenafil Citrate sourced via TeleMed ($6.26/mo cash pay without insurance prior authorization).