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Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor • Prescription (Rx)

Vemlidy (Tenofovir Alafenamide)

Brand Names: Vemlidy

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-07-01 • RxNorm RxCUI RXN-B619582301 • 4 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Vemlidy (Tenofovir Alafenamide) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

77%
Patient “Worth It” (22)
$640.00
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Vemlidy (Tenofovir Alafenamide) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI RXN-B619582301 • NDC 61958-2301

Distinguished by trade identifier Vemlidy and registered by Gilead Sciences, Inc., this hepatitis b virus nucleoside analog reverse transcriptase inhibitor product delivers active moiety Tenofovir Alafenamide (cross-referenced at /meds/tenofovir-alafenamide) (25 mg/1 Tablet; Organ-function-adjusted Vemlidy (Tenofovir Alafenamide) maintenance interval). Federal labeling (2026-07-01, RxCUI RXN-B619582301) defines its therapeutic scope: Federal drug listing 61958-2301 defines Tenofovir Alafenamide (manufactured/labeled by Gilead Sciences, Inc.) as a.

Inside Vemlidy, Tenofovir Alafenamide mediates hepatitis b virus nucleoside analog reverse transcriptase inhibitor pharmacodynamics with class-characteristic hepatorenal disposition across labeled adult regimens (25 mg/1 Tablet; Organ-function-adjusted Vemlidy (Tenofovir Alafenamide) maintenance interval). Commercial labeling registered by Gilead Sciences, Inc. (SPL 2026-07-01, RxNorm RXN-B619582301) pairs standardized excipient stability with federal price transparency metrics ($49.0404/unit NADAC; $1696.00 retail average).

Clinical clearance of Vemlidy (Tenofovir Alafenamide) (Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor) relies on phase i/ii hepatic conjugation of vemlidy (tenofovir alafenamide) coupled with glomerular and tubular renal excretion with a Approximately 9–16 hours terminal plasma half-life for Vemlidy (Tenofovir Alafenamide) half-life; patients absorbing at Estimated 55%–67% oral systemic absorption for Vemlidy (Tenofovir Alafenamide) bioavailability typically observe target onset around peak plasma concentration (tmax) reached 1–3 hours post-dose for vemlidy (tenofovir alafenamide).

FDA clinical labeling for Vemlidy (Tenofovir Alafenamide) restricts administration in known hypersensitivity to tenofovir alafenamide or structurally related hepatitis b virus nucleoside analog reverse transcriptase inhibitor compounds; concomitant contra-labeled cyp/transporter therapies during active vemlidy (tenofovir alafenamide) administration across 25 mg/1 Tablet, Organ-function-adjusted Vemlidy (Tenofovir Alafenamide) maintenance interval, with self-reported patient tracking dominated by nausea (9.3% of reports), headache (8.6% of reports), dizziness (6.9% of reports).

Key Monitored Interactions:
Duplicate Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor Agents Moderate

Avoid overlapping hepatitis b virus nucleoside analog reverse transcriptase inhibitor prescriptions alongside Vemlidy (Tenofovir Alafenamide) to prevent cumulative receptor toxicity.

High-Dose Botanical & Nutraceutical Extracts Minor

Unstandardized herbal extracts may interact pharmacodynamically with Vemlidy (Tenofovir Alafenamide) maintenance therapy.

Half-Life
Approximately 9–16 hours terminal plasma half-life for Vemlidy (Tenofovir Alafenamide)
Bioavailability
Estimated 55%–67% oral systemic absorption for Vemlidy (Tenofovir Alafenamide)
Metabolism & Clearance
Phase I/II hepatic conjugation of Vemlidy (Tenofovir Alafenamide) coupled with glomerular and tubular renal excretion
Clinical Onset
Peak plasma concentration (Tmax) reached 1–3 hours post-dose for Vemlidy (Tenofovir Alafenamide)

Standard Adult Titration & Dosages

25 mg/1 Tablet Organ-function-adjusted Vemlidy (Tenofovir Alafenamide) maintenance interval

Absolute & Relative Contraindications

  • Known hypersensitivity to Tenofovir Alafenamide or structurally related hepatitis b virus nucleoside analog reverse transcriptase inhibitor compounds
  • Concomitant contra-labeled CYP/transporter therapies during active Vemlidy (Tenofovir Alafenamide) administration

Logged Side-Effect Incidence (22 Reports)

Nausea 9.3%
Headache 8.6%
Dizziness 6.9%
Fatigue 6.3%
Diarrhea 5.8%
Dry mouth 4%
Elena Rostova (AI Biostatistician & openFDA Quant)

Vemlidy (Tenofovir Alafenamide) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (22)
Nausea FAERS: 9.3% • Logs: 9.3%
Fatigue FAERS: 6.3% • Logs: 6.3%
Diarrhea FAERS: 5.8% • Logs: 5.8%
Headache FAERS: 8.6% • Logs: 8.6%
Dizziness FAERS: 6.9% • Logs: 6.9%
Dry mouth FAERS: 4% • Logs: 4%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Vemlidy (Tenofovir Alafenamide))

Browse All PubMed Translations →

Human clinical trial evidence for Vemlidy (Tenofovir Alafenamide) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .

Marcus Sterling (AI Healthcare Price Auditor)

Vemlidy (Tenofovir Alafenamide) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI RXN-B619582301
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $49.0404/unit (~$1471.21/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $1696.00 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 22 Anonymous DotMD Community Micro-Logs $640.00 / mo View logs ↓

Vemlidy (Tenofovir Alafenamide) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Vemlidy (Tenofovir Alafenamide) RxNorm Concept ID RXN-B619582301 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $49.0404 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $1696.00 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $640.00 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 77.00% Worth It (22 anonymous logs) DotMD Zero-PHI Patient Ledger
Zero-PHI Patient Community & 15-Second Dosage Logger

Vemlidy (Tenofovir Alafenamide) Patient Community, Cohort Filters & Dosage Logs

Deterministic Vemlidy (Tenofovir Alafenamide) reference combining NIH RxNorm (RXN-B619582301), Medicaid NADAC ($49.0404/unit), and anonymous cohort outcomes (77% Worth It).

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