✓ Translated by DotMD AI Clinical Council Source: The Journal of clinical endocrinology and metabolism • Randomized Controlled Trial
Verify Primary Source: NIH PubMed PMID #9661595 ↗

Randomized Controlled Trial: Effects of estrogen or testosterone on self-reported sexual responses and behaviors in hypogonadal adolescents

Original Paper Title: “Effects of estrogen or testosterone on self-reported sexual responses and behaviors in hypogonadal adolescents”

Elena Rostova (AI Quant) Rigor Score
88 / 100
Sample Size (Participants)
Systematic Review
Evidence Classification
Randomized Controlled Trial
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • We noted some gender differences for thinking about sex, sexual "turn-on," and the nature of sexual behavior. The administration of physiological doses of sex steroids to boys or girls with delayed puberty have few effects on sexual behaviors and responses.
  • Study Design & Sample: Randomized Controlled Trial published in The Journal of clinical endocrinology and metabolism (Multi-cohort synthesis).
  • Biostatistical Rigor Score: 88/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in The Journal of clinical endocrinology and metabolism (1998), this randomized controlled trial evaluating human clinical outcomes investigated: The purpose of this study was to investigate the effects of administration of sex steroids on self-reported sexual responses and behaviors in hypogonadal adolescents. Key clinical takeaway: We noted some gender differences for thinking about sex, sexual "turn-on," and the nature of sexual behavior. The administration of physiological doses of sex steroids to boys or girls with delayed puberty have few effects on sexual behaviors and responses.

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (The Journal of clinical endocrinology and metabolism, 1998-07-15; Randomized Controlled Trial; Rigor 88/100): We noted some gender differences for thinking about sex, sexual "turn-on," and the nature of sexual behavior. The administration of physiological doses of sex steroids to boys or girls with delayed puberty have few effects on sexual behaviors and responses.

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Randomized Controlled Trial). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

Related DotMD Clinical Hubs & Price Ledgers

Rx: 3-6oz-biest-2-5-estrogen-cream-estriol-estradiol-estrogen-cream → Rx: biest-5-0-estrogen-cream-3-6oz-estriol-estradiol → Rx: testosterone-cypionate → Rx: testosterone → Condition: hormones → Condition: safety →
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