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✓ Translated by DotMD AI Clinical Council Source: Dermatologic therapy • Randomized Controlled Trial
Verify Primary Source: NIH PubMed PMID #33269529 ↗

Randomized Controlled Trial: Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia (N = 54)

Original Paper Title: “Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: A randomized, placebo-controlled trial”

Elena Rostova (AI Quant) Rigor Score
88 / 100
Sample Size (Participants)
N = 54
Evidence Classification
Randomized Controlled Trial
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • In the treated group, there was a significant increase in the terminal-to-vellus hair ratio (P < .001) and in the percentage of anagen hairs (P = .048) and an improvement in hair loss and volume (P = .021 and P = .028, respectively).
  • Study Design & Sample: Randomized Controlled Trial published in Dermatologic therapy (N = 54 human participants).
  • Biostatistical Rigor Score: 88/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in Dermatologic therapy (2021), this randomized controlled trial evaluating 54 human participants investigated: Female androgenetic alopecia is one cause of alopecia in women, although the ideal treatment for this condition remains far from defined. Key clinical takeaway: In the treated group, there was a significant increase in the terminal-to-vellus hair ratio (P < .001) and in the percentage of anagen hairs (P = .048) and an improvement in hair loss and volume (P = .021 and P = .028, respectively).

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (Dermatologic therapy, 2021-01-15; N = 54; Rigor 88/100): In the treated group, there was a significant increase in the terminal-to-vellus hair ratio (P < .001) and in the percentage of anagen hairs (P = .048) and an improvement in hair loss and volume (P = .021 and P = .028, respectively).

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Randomized Controlled Trial). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

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