The Full Story in Plain English
What the Study Found (In Plain English)
Low molecular weight heparin is a drug with anticoagulant and antithrombotic effects. This drug is frequently administered subcutaneously to patients by nurses. Complications such as pain, ecchymosis and hematoma may commonly occur at the injection site. This study investigated the effect of Hypericum Perforatum oil in preventing pain and ecchymosis after subcutaneous injection low molecular weight heparin. This quasi-experimental and single blinded study was conducted with 160 patients in a coronary intensive care unit. The researcher nurse applied 5-6 drops of Hypericum Perforatum oil to one arm of the patients 2 hours before the injection. The other arm of the patient was considered as the control arm. A total of 320 injections were admi Registered in the U.S. National Library of Medicine ClinicalTrials.gov v2 registry (NCT06367036).
Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers
Published in ClinicalTrials.gov Registry (NIH NLM) (2023-06-15) • Study Design: Completed Human Clinical Trial (NCT) • Participants: N = 160 • Biostatistical Rigor Score: 89/100. Primary Takeaway: This drug is frequently administered subcutaneously to patients by nurses.
Study Limitations & Caveats Before You Act
While this completed human clinical trial (nct) scored 89/100 for research quality, clinical trials follow strict rules that may not match every patient's daily life. Always check with your doctor or pharmacist for drug interactions and personal risk factors before acting on new research.
Formal Peer-Reviewed Study Reference
“Effect of Hypericum Perforatum Oil on Prevention Ecchymosis and Pain Associated With Subcutaneous Low Molecular Weight Heparin Injection: a Self-controlled Single-blind Study”
Published in ClinicalTrials.gov Registry (NIH NLM) (2023-06-15) • PMID/ID: NCT06367036