✓ Translated by DotMD AI Clinical Council Source: Pain management • Phase III Randomized Trial
Verify Primary Source: NIH PubMed PMID #33094682 ↗

Phase III Randomized Trial: Preoperative intravenous meloxicam for moderate-to-severe pain in the immediate post-operative period (N = 27)

Original Paper Title: “Preoperative intravenous meloxicam for moderate-to-severe pain in the immediate post-operative period: a Phase IIIb randomized clinical trial in 55 patients undergoing primary open or laparoscopic colorectal surgery with bowel resection and/or anastomosis”

Elena Rostova (AI Quant) Rigor Score
88 / 100
Sample Size (Participants)
N = 27
Evidence Classification
Phase III Randomized Trial
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • Conclusion: Meloxicam IV was generally well tolerated and associated with decreased opioid consumption, lower resource utilization and functional benefits. Clinical Trial Registration: NCT03323385
  • Study Design & Sample: Phase III Randomized Trial published in Pain management (N = 27 human participants).
  • Biostatistical Rigor Score: 88/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in Pain management (2021), this phase iii randomized trial evaluating 27 human participants investigated: Aim: Evaluate safety/efficacy of intravenous meloxicam in a colorectal enhanced recovery after surgery protocol. Key clinical takeaway: Conclusion: Meloxicam IV was generally well tolerated and associated with decreased opioid consumption, lower resource utilization and functional benefits. Clinical Trial Registration: NCT03323385

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (Pain management, 2021-01-15; N = 27; Rigor 88/100): Conclusion: Meloxicam IV was generally well tolerated and associated with decreased opioid consumption, lower resource utilization and functional benefits. Clinical Trial Registration: NCT03323385

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Phase III Randomized Trial). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

Related DotMD Clinical Hubs & Price Ledgers

Rx: meloxicam → Rx: zybic-meloxicam → Rx: period-pills-by-biikay-acetaminophen-ibuprofen → Rx: crest-pro-health-cetylpyridinium-chloride → Condition: surgery → Condition: other-female-genital-prolapse → Condition: female-genital-prolapse →
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