✓ Translated by DotMD AI Clinical Council Source: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] • Phase III Randomized Trial
Verify Primary Source: NIH PubMed PMID #32970162 ↗

Phase III Randomized Trial: Results of a randomized controlled phase III trial: efficacy of polyphenol-containing cystus® tea mouthwash solution for the reduction of mucositis in head and neck cancer patients undergoing external beam radiotherapy (N = 55)

Original Paper Title: “Results of a randomized controlled phase III trial: efficacy of polyphenol-containing cystus® tea mouthwash solution for the reduction of mucositis in head and neck cancer patients undergoing external beam radiotherapy”

Elena Rostova (AI Quant) Rigor Score
82 / 100
Sample Size (Participants)
N = 55
Evidence Classification
Phase III Randomized Trial
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • Cystus® and sage tea have a similar effect on the occurrence of radiation-induced mucositis regarding latency and incidence. Cystus® tea mouthwash solution is tolerated well and can be applied in addition to intensive oral care and hygiene along with the application of fluorides.
  • Study Design & Sample: Phase III Randomized Trial published in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (N = 55 human participants).
  • Biostatistical Rigor Score: 82/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2021), this phase iii randomized trial evaluating 55 human participants investigated: To determine the effect of Cystus® tea (Naturprodukte Dr. Key clinical takeaway: Cystus® and sage tea have a similar effect on the occurrence of radiation-induced mucositis regarding latency and incidence. Cystus® tea mouthwash solution is tolerated well and can be applied in addition to intensive oral care and hygiene along with the application of fluorides.

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2021-01-15; N = 55; Rigor 82/100): Cystus® and sage tea have a similar effect on the occurrence of radiation-induced mucositis regarding latency and incidence. Cystus® tea mouthwash solution is tolerated well and can be applied in addition to intensive oral care and hygiene along with the application of fluorides.

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Phase III Randomized Trial). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

Related DotMD Clinical Hubs & Price Ledgers

Condition: head-and-neck-cancer → Condition: stomatitis →
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